| T6057 |
URMC-099
|
1229582-33-5
|
98%
|
|
|
URMC-099 is an orally bioavailable, brain penetrant MLK inhibitor (IC50: 19/42/14/150 nM, for MLK1/MLK2/MLK3/DLK), and also inhibits LRRK2 activity (IC50: 11 nM)...
|
| T1507 |
Streptozocin
|
18883-66-4
|
98%
|
|
|
Streptozocin (NSC-85998) is an antibiotic that induces DNA methylation. Streptozocin is toxic to insulin-producing pancreatic islet B-cells and is commonly used ...
|
| T9985 |
Methyl methanesulfonate
|
66-27-3
|
98%
|
|
|
Methyl methanesulfonate is a DNA alkylator that modifies adenine (3-methyladenine) and guanine (7-methyladenine) respectively, resulting in base mismatch and rep...
|
| T1241 |
Altretamine
|
645-05-6
|
98%
|
|
|
Altretamine (ENT-50852) is an alkylating agent with antineoplastic activity.
|
| T17212 |
VAL-083
|
23261-20-3
|
|
|
|
VAL-083 (Dianhydrogalactitol) is an alkylating compound that creates N7 methylation on DNA. It also has antitumor activity.
|
| T73457 |
DN-1289
|
|
100%
|
|
|
DN-1289 is an orally available, blood-brain barrier-crossing, selective and potent inhibitor with an IC50 value of 17 nM for di-leucine zipper kinase (DLK) and 4...
|
| T4350 |
Palifosfamide
|
31645-39-3
|
97%
|
|
|
Palifosfamide (Isophosphamide mustard) lysine (ZIO-201) is a stable form of palifosfamide. Palifosfamide lysine has broad activity in sarcoma lines in vitro. The...
|
| T7221 |
Satraplatin
|
129580-63-8
|
98%
|
|
|
Satraplatin (BMS182751) is an orally available antineoplastic platinum(IV) complex.Satraplatin has a favorable toxicity profile and appears to have clinical acti...
|
| T1250 |
Thio-TEPA
|
52-24-4
|
98%
|
|
|
Thio-TEPA (Tiofosyl) is a polyfunctional, organophosphorus alkylating agent with antineoplastic activity.
|
| T7539 |
O6-Benzylguanine
|
19916-73-5
|
98%
|
|
|
O6-Benzylguanine is a guanine analog with antineoplastic activity,and is a potent O6-alkylguanine DNA alkyltransferase (AGT) inactivator.
|
| T15771 |
Lobaplatin
|
135558-11-1
|
98.00%
|
|
|
Lobaplatin (D-19466) (D-19466) is a diastereometric mixture of platinum(II) complexe. Lobaplatin (D-19466) is a third-generation platinum anti-neoplastic agent w...
|
| T26978 |
CEP-40125
|
1456608-94-8
|
98.05%
|
|
|
CEP-40125 (RXDX-107) is a DNA alkylating agent for the study of advanced solid tumors.
|
| T3707 |
GNE-3511
|
1496581-76-0
|
98.64%
|
|
|
GNE-3511 is a potent and selective dual leucine zipper kinase inhibitors.
|
| T11120 |
Duocarmycin TM
|
157922-77-5
|
99.15%
|
|
|
Duocarmycin TM is a DNA alkylator. Duocarmycin TM is an exceptionally potent antitumor antibiotic.
|
| T17159 |
Treosulfan
|
299-75-2
|
99.26%
|
|
|
Treosulfan (Treosulphan) is a bifunctional alkylating agent. It also has activity in ovarian cancer and other solid tumor types.
|
| T0975 |
Chlorambucil
|
305-03-3
|
99.58%
|
|
|
Chlorambucil (CB-1348) is an orally-active antineoplastic aromatic nitrogen mustard. Chlorambucil alkylates and cross-links DNA during all phases of the cell cyc...
|
| T21297 |
Miriplatin hydrate
|
250159-48-9
|
99.6%
|
|
|
Miriplatin hydrate (SM-11355 (hydrate)) (MPT) is a novel platinum complex used in TACE that shows promise for the treatment of hepatocellular carcinoma (HCC). Mi...
|
| T2495 |
Lomeguatrib
|
192441-08-0
|
99.62%
|
|
|
Lomeguatrib (PaTrin-2), a modified guanine base, inhibits the activity of DNA repair protein O(6)-alkylguanine-DNA alkyltransferase (MGMT) .
|
| T6798 |
Tretazicar
|
21919-05-1
|
99.7%
|
|
|
CB1954(Tretazicar (NSC-115829)), an anticancer prodrug, is activated by NAD(P)H quinone oxidoreductase 2. It is converted in the presence of the enzyme NQO2 and ...
|
| T0923 |
Busulfan
|
55-98-1
|
99.77%
|
|
|
Busulfan (Busulphan) is a synthetic derivative of dimethane-sulfonate with antineoplastic and cytotoxic properties. Although its mechanism of action is not fully...
|
