T17212 |
VAL-083
|
23261-20-3
|
|
|
VAL-083 (Dianhydrogalactitol) is an alkylating compound that creates N7 methylation on DNA. It also has antitumor activity.
|
T1488 |
Procarbazine hydrochloride
|
366-70-1
|
|
|
Procarbazine hydrochloride (NSC-77213 HCl) is the hydrochloride salt of a methylhydrazine derivative with antineoplastic and mutagenic activities. Although the e...
|
T4459 |
PK11000
|
38275-34-2
|
100%
|
|
PK11000 is a p53 targeting compound, has anti-tumor activities through activation of unstable p53.
|
T4570 |
Pipobroman
|
54-91-1
|
93.01%
|
|
Pipobroman (Vercyte) is an anti-cancer drug that probably acts as an alkylating agent. Pipobroman has well documented clinical activity in polycythemia vera (PV)...
|
T4350 |
Palifosfamide
|
31645-39-3
|
97%
|
|
Palifosfamide (Isophosphamide mustard) lysine (ZIO-201) is a stable form of palifosfamide. Palifosfamide lysine has broad activity in sarcoma lines in vitro. The...
|
T8380 |
Bendamustine
|
16506-27-7
|
97.38%
|
|
Bendamustine (SDX105) for the treatment of Non-Hodgkin Lymphomas and Chronic Lymphocytic Leukemia
|
T1798 |
RITA
|
213261-59-7
|
97.76%
|
|
RITA (NSC-652287)(NSC-652287) induced cross-links of both DNA-DNA and DNA-protein with no detectable DNA single-strand breaks. RITA, like nutlin-3, can disrupt t...
|
T7221 |
Satraplatin
|
129580-63-8
|
98%
|
|
Satraplatin (BMS182751) is an orally available antineoplastic platinum(IV) complex.Satraplatin has a favorable toxicity profile and appears to have clinical acti...
|
T1250 |
Thio-TEPA
|
52-24-4
|
98%
|
|
Thio-TEPA (Tiofosyl) is a polyfunctional, organophosphorus alkylating agent with antineoplastic activity.
|
T4368 |
Miriplatin
|
141977-79-9
|
98%
|
|
Miriplatin (SM-11355) (SM-11355) is a platinum complex used in TACE that has promise for the therapy of hepatocellular carcinoma (HCC).
|
T0095 |
Bendamustine hydrochloride
|
3543-75-7
|
98.03%
|
|
Bendamustine hydrochloride (EP-3101) (IC50 of 50 μM) is an alkylating agent associated with DNA damage.
|
T22857 |
Illudin S
|
1149-99-1
|
98.15%
|
|
Illudin S (ILS) is a fungal sesquiterpene secondary metabolite with potent genotoxic and cytotoxic properties.
|
T0707L |
Cyclophosphamide
|
50-18-0
|
98.26%
|
|
Cyclophosphamide is an alkylating agent used in the treatment of several forms of cancer including leukemias, lymphomas and breast cancer.
|
T1507 |
Streptozocin
|
18883-66-4
|
98.89%
|
|
Streptozocin (NSC-85998) is an antibiotic that induces DNA methylation. Streptozocin is toxic to insulin-producing pancreatic islet B-cells and is commonly used ...
|
T4558 |
Trioxsalen
|
3902-71-4
|
98.96%
|
|
Trioxsalen (Trioxysalen) is a furanocoumarin and a psoralen derivative, in conjunction with UV-A for phototherapy treatment of vitiligo and hand eczema. After ph...
|
T5017 |
Nimustine Hydrochloride
|
55661-38-6
|
99.2%
|
|
Nimustine Hydrochloride (Nidran hydrochloride) has been used in trials studying the treatment of Glioblastoma.
|
T17159 |
Treosulfan
|
299-75-2
|
99.26%
|
|
Treosulfan (Treosulphan) is a bifunctional alkylating agent. It also has activity in ovarian cancer and other solid tumor types.
|
T16871 |
Semustine
|
13909-09-6
|
99.55%
|
|
Semustine, a DNA alkylating agent, is a cancer chemotherapy compound that is nephrotoxic in patients with malignant melanoma receiving adjuvant chemotherapy for ...
|
T36528 |
Illudin M
|
1146-04-9
|
99.56%
|
|
Illudin M is a cytotoxic sesquiterpene from the fungus O. illudens that alkylates DNA. It has a cytotoxicity of 6-100 nM against HL-60 human leukemia cells.Illud...
|
T0975 |
Chlorambucil
|
305-03-3
|
99.58%
|
|
Chlorambucil (CB-1348) is an orally-active antineoplastic aromatic nitrogen mustard. Chlorambucil alkylates and cross-links DNA during all phases of the cell cyc...
|