| T0809 |
Dicoumarol
|
66-76-2
|
98%
|
|
|
Dicoumarol (Dicumarol) is a hydroxycoumarin originally isolated from molding sweet-clover hay, with anticoagulant and vitamin K depletion activities. Dicoumarol ...
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| T15173 |
DSM265
|
1282041-94-4
|
98%
|
|
|
DSM265 (PfSPZ) is a dihydroorotic acid dehydrogenase inhibitor with antimalarial activity (IC50: 8.9 nM).DSM265 inhibits the growth of Pf3D7 parasites and can be...
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| T9974 |
Antiproliferative agent-13
|
663214-48-0
|
98%
|
|
|
Antiproliferative agent-13 is a compound with antiproliferative activity.
|
| T3444 |
Merimepodib
|
198821-22-6
|
98%
|
|
|
Merimepodib (VX-497) is a novel noncompetitive inhibitor of Inosine monophosphate dehydrogenase(IMPDH).
|
| T37190 |
L-Allylglycine
|
16338-48-0
|
98%
|
|
|
L-Allylglycine is an amino acid derivative that reduces glutamate decarboxylase (GAD) activity by 60% when administered at a dose of 39.8 μmol/g per hour ex vivo...
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| T13019 |
Succinyl phosphonate trisodium salt
|
864167-45-3
|
98%
|
|
|
Succinyl phosphonate trisodium salt is an inhibitor of α-ketoglutarate dehydrogenase (KGDHC)
|
| T40686 |
Tiazofurin
|
60084-10-8
|
98%
|
|
|
Tiazofurin (NSC-286193) is a synthetic nucleoside analogue with antineoplastic activity. Tiazofurin is anabolized intracellularly to tiazole-4-carboxamide adenin...
|
| T0897 |
Nitrofurazone
|
59-87-0
|
98%
|
|
|
Nitrofurazone (Furacilin) is a topical anti-infective agent effective against gram-negative and gram-positive bacteria. It is used for superficial WOUNDS AND INJ...
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| T10146 |
4-Hydroxyderricin
|
55912-03-3
|
98%
|
|
|
4-Hydroxyderricin, a potent and selective MAO-B inhibitor (IC50: 3.43 μM), is the main active ingredient of Angelica sinensis, which mildly inhibits dopamine β-h...
|
| T9494 |
Imidazole-5-propionic acid
|
1074-59-5
|
98%
|
|
|
Imidazole-5-propionic acid (Imidazolylpropionic acid) is a product of histidine metabolism and may involve oxidation or transamination. Imidazole-5-propionic aci...
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| T4173 |
R162
|
64302-87-0
|
98%
|
|
|
R162 is an effective glutamate dehydrogenase 1 (GDH1) inhibitor.
|
| T14388 |
AZD 4017
|
1024033-43-9
|
|
|
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AZD 4017 is an inhibitor of 11β-Hydroxysteroid Dehydrogenase Type 1(11β-HSD1) (IC50: 7 nM).
|
| T15551 |
IDH889
|
1429179-07-6
|
|
|
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IDH889 is a brain penetrant, an allosteric and mutant specific IDH1 inhibitor. IDH889 has effective selectivity for IDH1 R132* mutations (IC50s: 0.02 μM, 0.072 μ...
|
| TJS1382 |
Taraxerone
|
514-07-8
|
|
|
|
Taraxerone has allelopathic and antifungal effects.Taraxerone prevents catalase, superoxide dismutase, and reduces glutathione concentrations from the decrease i...
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| T12438 |
PfDHODH-IN-1
|
183945-55-3
|
|
|
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PfDHODH-IN-1 is an analogue of the active Leflunomide metabolite, has antimalarial activity.
|
| T12196 |
NCT-505
|
2231079-74-4
|
|
|
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NCT-505 is a potent and selective inhibitor of aldehyde dehydrogenase (ALDH1A1, IC50 = 7 nM) and a weak inhibitor of hALDH1A2, hALDH1A3, hALDH2, hALDH3A1 with IC...
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| T10140 |
4-Diethylaminobenzaldehyde
|
120-21-8
|
|
|
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4-Diethylaminobenzaldehyde is a reversible aldehyde dehydrogenase (ALDH) inhibitor (Ki: 4 nM for ALDH1). It displays a potent anti-androgenic effect (IC50: 1.71μ...
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| T19831 |
Sodium Oxamate
|
565-73-1
|
|
|
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Sodium Oxamate (Oxamic acid sodium salt) is an LDH inhibitor that specifically inhibits LDHA. Sodium Oxamate has antitumor activity and induces cell cycle arrest...
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| T11021 |
DHODH-IN-12
|
1263303-93-0
|
100%
|
|
|
DHODH-IN-12 is a leflunomide derivative and a weak dihydrorotate dehydrogenase (DHODH) inhibitor with a pKa of 5.07.
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| T7741 |
DS-1001b
|
1898207-64-1
|
100%
|
|
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DS-1001b is an inhibitor of mutant IDH-1 (Isocitrate Dehydrogenase-1)
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