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Dopamine Receptor

Dopamine receptors are a class of G protein-coupled receptors that are prominent in the vertebrate central nervous system (CNS). Dopamine receptors activate different effectors through not only G-protein coupling, but also signaling through different protein (dopamine receptor-interacting proteins) interactions.
Cat. No. 製品名 CAS No. Purity Chemical Structure
T7153 Vanoxerine dihydrochloride 67469-78-7 98%
Vanoxerine dihydrochloride (GBR-12909 dihydrochloride) is a potent inhibitor that blocks dopamine uptake (IC50 : 1-51 nM)
T11087 DOV-216,303 Free Base 66504-40-3 98%
DOV-216,303 Free Base (DOV-216303) is an inhibitor of serotonin, norepinephrine, and dopamine reuptake with with IC50s of 14, 20 and 78 nM. DOV-216,303 Free Base...
T22904 L-745870 trihydrochloride 866021-03-6 98%
L-745870 trihydrochloride is a highly potent and selective D4 dopamine receptor antagonist.
T12606 Quinpirole Hydrochloride 85798-08-9 98%
Quinpirole Hydrochloride (LY 171555), as an agonist with high affinity for dopamine receptor D2/D3, has been widely used to study the function of dopamine recept...
T76882 Talquetamab 2226212-40-2 98%
Talquetamab (JNJ-64407564) is a T-cell retargeting GPRC5D bispecific antibody for multiple myeloma with antitumor activity that induces T-cell-mediated killing o...
T6142 PD128907 HCl 112960-16-4 98%
PD128907 HCl is a potent and selective dopamine D3 receptor agonist, with EC50 of 0.64 nM, exhibits 53-fold selectivity over dopamine D2 receptor.
T9827 Carfenazine 2622-30-2 98%
carfenazine targets the Dopamine receptor and is used for schizophrenia research.
T60075 Dopamine D2 receptor agonist-2 1610591-93-9 98%
Dopamine D2 receptor agonist-2 (Dopamine D2 Receptor) is a ligand targeting the dopamine D2 receptor.
T7553 (+)-PD 128907 hydrochloride 300576-59-4 98%
(+)-PD 128907 hydrochloride is an agonist of D3 dopamine receptor .
T23380 Sonepiprazole 170858-33-0 98%
Sonepiprazole (PNU-101387G) is a chemical compound known for its selective antagonistic properties toward D4 dopamine receptors, exhibiting dissociation constant...
T6951 Pramipexole dihydrochloride hydrate 191217-81-9 98%
Pramipexole dihydrochloride hydrate (Mirapex) is the hydrochloride salt of pramipexole, a benzothiazole derivative. As a nonergot dopamine agonist, pramipexole b...
T2092 Amitifadine hydrochloride 410074-74-7 98%
Amitifadine hydrochloride (EB-1010 hydrochloride) is a triple reuptake inhibitor (TRI) or serotonin-norepinephrine-dopamine reuptake inhibitor (SNDRI).
T8385 Metoclopramide hydrochloride hydrate 54143-57-6 98%
Metoclopramide hydrochloride hydrate (Metoclopramide monohydrochloride monohydrate) is a dopamine D2 antagonist that is a drug used for digestive dysfunction. It...
T0338 Minaprine 25905-77-5 98%
Minaprine is a reversible inhibitor of MAO-A, used in the treatment of various depressive states.
T15270 Fananserin 127625-29-0 98%
Fananserin is an effective, selective and oral active antagonist of 5-HT2 (Ki = 0.37 nM for the rat 5-HT2A). Fananserin is an antagonist of human D4 receptor (Ki...
T5954 Methyldopa hydrate 41372-08-1
Methyldopa hydrate (MK-351 hydrate) is a DOPA decarboxylase inhibitor and indirect α2-adrenergic receptor agonist used to treat hypertension. It inhibits the sym...
T0785 Dexchlorpheniramine Maleate 2438-32-6
Dexchlorpheniramine Maleate (S-(+)-Chlorpheniramine maleate salt) is an antihistamine with anticholinergic properties used to treat allergic conditions such as h...
T14767 BP 897 hydrochloride 314776-92-6
BP 897 is a potent and selective agonist of dopamine D3 receptor and it is a weak dopamine D2 receptor antagonist, with Kis of 0.92 nM and 61 nM for D3 and D2 re...
T8423 ML417 1386162-69-1
ML417 is a selective and brain penetrant agonist of D3 Dopamine (EC50 : 38 nM).
T8653 DOPEXAMINE 86197-47-9
Dopexamine is a dopaminergic agonist
Vanoxerine dihydrochloride
T7153
Vanoxerine dihydrochloride (GBR-12909 dihydrochloride) is a potent inhibitor that blocks dopamine uptake (IC50 : 1-51 nM)
DOV-216,303 Free Base
T11087
DOV-216,303 Free Base (DOV-216303) is an inhibitor of serotonin, norepinephrine, and dopamine reuptake with with IC50s of 14, 20 and 78 nM. DOV-216,303 Free Base...
L-745870 trihydrochloride
T22904
L-745870 trihydrochloride is a highly potent and selective D4 dopamine receptor antagonist.
Quinpirole Hydrochloride
T12606
Quinpirole Hydrochloride (LY 171555), as an agonist with high affinity for dopamine receptor D2/D3, has been widely used to study the function of dopamine recept...
Talquetamab
T76882
Talquetamab (JNJ-64407564) is a T-cell retargeting GPRC5D bispecific antibody for multiple myeloma with antitumor activity that induces T-cell-mediated killing o...
PD128907 HCl
T6142
PD128907 HCl is a potent and selective dopamine D3 receptor agonist, with EC50 of 0.64 nM, exhibits 53-fold selectivity over dopamine D2 receptor.
carfenazine
T9827
carfenazine targets the Dopamine receptor and is used for schizophrenia research.
Dopamine D2 receptor agonist-2
T60075
Dopamine D2 receptor agonist-2 (Dopamine D2 Receptor) is a ligand targeting the dopamine D2 receptor.
(+)-PD 128907 hydrochloride
T7553
(+)-PD 128907 hydrochloride is an agonist of D3 dopamine receptor .
Sonepiprazole
T23380
Sonepiprazole (PNU-101387G) is a chemical compound known for its selective antagonistic properties toward D4 dopamine receptors, exhibiting dissociation constant...
Pramipexole dihydrochloride hydrate
T6951
Pramipexole dihydrochloride hydrate (Mirapex) is the hydrochloride salt of pramipexole, a benzothiazole derivative. As a nonergot dopamine agonist, pramipexole b...
Amitifadine hydrochloride
T2092
Amitifadine hydrochloride (EB-1010 hydrochloride) is a triple reuptake inhibitor (TRI) or serotonin-norepinephrine-dopamine reuptake inhibitor (SNDRI).
Metoclopramide hydrochloride hydrate
T8385
Metoclopramide hydrochloride hydrate (Metoclopramide monohydrochloride monohydrate) is a dopamine D2 antagonist that is a drug used for digestive dysfunction. It...
Minaprine
T0338
Minaprine is a reversible inhibitor of MAO-A, used in the treatment of various depressive states.
Fananserin
T15270
Fananserin is an effective, selective and oral active antagonist of 5-HT2 (Ki = 0.37 nM for the rat 5-HT2A). Fananserin is an antagonist of human D4 receptor (Ki...
Methyldopa hydrate
T5954
Methyldopa hydrate (MK-351 hydrate) is a DOPA decarboxylase inhibitor and indirect α2-adrenergic receptor agonist used to treat hypertension. It inhibits the sym...
Dexchlorpheniramine Maleate
T0785
Dexchlorpheniramine Maleate (S-(+)-Chlorpheniramine maleate salt) is an antihistamine with anticholinergic properties used to treat allergic conditions such as h...
BP 897 hydrochloride
T14767
BP 897 is a potent and selective agonist of dopamine D3 receptor and it is a weak dopamine D2 receptor antagonist, with Kis of 0.92 nM and 61 nM for D3 and D2 re...
ML417
T8423
ML417 is a selective and brain penetrant agonist of D3 Dopamine (EC50 : 38 nM).
DOPEXAMINE
T8653
Dopexamine is a dopaminergic agonist
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