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Dopamine Receptor

Dopamine receptors are a class of G protein-coupled receptors that are prominent in the vertebrate central nervous system (CNS). Dopamine receptors activate different effectors through not only G-protein coupling, but also signaling through different protein (dopamine receptor-interacting proteins) interactions.
Cat. No. 製品名 CAS No. Purity Chemical Structure
T4081 MPTP hydrochloride 23007-85-4 98%
MPTP hydrochloride (MPTP-hydrochloride) is a precusor of MPP+ which is toxic to dopaminergic neurons and causes Parkinsonism.
T7153 Vanoxerine dihydrochloride 67469-78-7 98%
Vanoxerine dihydrochloride (GBR-12909 dihydrochloride) is a potent inhibitor that blocks dopamine uptake (IC50 : 1-51 nM)
T16759 Ritanserin 87051-43-2 98%
Ritanserin (R 55667) is a highly effective, relatively selective, long-acting antagonist of 5-HT2 receptor (IC50: 0.9 nM), less active on Histamine H1, Dopamine ...
T12489L Pimethixene maleate 13187-06-9 98%
Pimethixene maleate (Pimetixene maleate) is a potent 5-HT2B receptor antagonist with sedative and antitussive activity.Pimethixene maleate inhibits 5-HT1A, 5-HT2...
T1517 Benserazide hydrochloride 14919-77-8 98%
Benserazide hydrochloride (Ro 4-4602) is a peripherally-acting L-amino acid decarboxylase (AAAD) or DOPA decarboxylase inhibitor.
T0806 Flunarizine dihydrochloride 30484-77-6 98%
Flunarizine dihydrochloride (R14950) is a selective calcium entry blocker with calmodulin binding properties and histamine H1 blocking activity. Flunarizine dihy...
T5954 Methyldopa hydrate 41372-08-1 98%
Methyldopa hydrate (MK-351 hydrate) is a DOPA decarboxylase inhibitor and indirect α2-adrenergic receptor agonist used to treat hypertension. It inhibits the sym...
T0136 Citicoline 987-78-0 98%
Citicoline (CDP-Choline) is an intermediate in the synthesis of phosphatidylcholine, a component of cell membranes. Citicoline exerts neuroprotective effects.
T61807 5-HT6/7 antagonist 1 131999-28-5 98%
5-HT6/7 antagonist 1 is a dual 5-HT6/7/2A and D2 receptor antagonist for the study of dementia and Alzheimer's disease.
T11087 DOV-216,303 Free Base 66504-40-3 98%
DOV-216,303 Free Base (DOV-216303) is an inhibitor of serotonin, norepinephrine, and dopamine reuptake with with IC50s of 14, 20 and 78 nM. DOV-216,303 Free Base...
T0785 Dexchlorpheniramine Maleate 2438-32-6 98%
Dexchlorpheniramine Maleate (S-(+)-Chlorpheniramine maleate salt) is an antihistamine with anticholinergic properties used to treat allergic conditions such as h...
T5158 N-Desmethylclozapine 6104-71-8 98%
N-Desmethylclozapine (Desmethylclozapine) is an antagonist of serotonin (5-HT) receptor subtype 5-HT2C (IC50: 7.1 nM). It also is an antagonist at dopamine D4 re...
T1476 Pramipexole 104632-26-0 98%
Pramipexole (SND 919) is a selective dopamine receptor agonist used in the therapy of Parkinson disease. Pramipexole therapy is associated with a low rate of tra...
T23382 Spiroxatrine 1054-88-2 98%
Spiroxatrine (R 5188) is a selective and potent 5-HT1α and α2-adrenergic dual antagonist with sedative activity and inhibitory effects on 5-HT1α, 5-HT1 β, 5-HT2,...
T0255 Clomipramine hydrochloride 17321-77-6 98%
Clomipramine hydrochloride (Anafranil) is a tricyclic antidepressant similar to IMIPRAMINE that selectively inhibits the uptake of serotonin in the brain. It is ...
T8423 ML417 1386162-69-1 98%
ML417 is a selective and brain penetrant agonist of D3 Dopamine (EC50 : 38 nM).
T0365 Thioridazine hydrochloride 130-61-0 98%
Thioridazine hydrochloride (Mellaril) , an antipsychotic drug, is used in the therapy of psychosis and schizophrenia and shows serotonin antagonism or D4 selecti...
T0185 Escitalopram 128196-01-0 98%
Escitalopram (Seroplex) is a furancarbonitrile that is one of the SEROTONIN UPTAKE INHIBITORS used as an antidepressant. The drug is also effective in reducing e...
T22904 L-745870 trihydrochloride 866021-03-6 98%
L-745870 trihydrochloride is a highly potent and selective D4 dopamine receptor antagonist.
T4297 Flibanserin 167933-07-5 98%
Flibanserin (Girosa) is a serotonergic antidepressant used to treat hypoactive sexual desire disorder. Flibanserin has been associated with a low rate of minor s...
MPTP hydrochloride
T4081
MPTP hydrochloride (MPTP-hydrochloride) is a precusor of MPP+ which is toxic to dopaminergic neurons and causes Parkinsonism.
Vanoxerine dihydrochloride
T7153
Vanoxerine dihydrochloride (GBR-12909 dihydrochloride) is a potent inhibitor that blocks dopamine uptake (IC50 : 1-51 nM)
Ritanserin
T16759
Ritanserin (R 55667) is a highly effective, relatively selective, long-acting antagonist of 5-HT2 receptor (IC50: 0.9 nM), less active on Histamine H1, Dopamine ...
Pimethixene maleate
T12489L
Pimethixene maleate (Pimetixene maleate) is a potent 5-HT2B receptor antagonist with sedative and antitussive activity.Pimethixene maleate inhibits 5-HT1A, 5-HT2...
Benserazide hydrochloride
T1517
Benserazide hydrochloride (Ro 4-4602) is a peripherally-acting L-amino acid decarboxylase (AAAD) or DOPA decarboxylase inhibitor.
Flunarizine dihydrochloride
T0806
Flunarizine dihydrochloride (R14950) is a selective calcium entry blocker with calmodulin binding properties and histamine H1 blocking activity. Flunarizine dihy...
Methyldopa hydrate
T5954
Methyldopa hydrate (MK-351 hydrate) is a DOPA decarboxylase inhibitor and indirect α2-adrenergic receptor agonist used to treat hypertension. It inhibits the sym...
Citicoline
T0136
Citicoline (CDP-Choline) is an intermediate in the synthesis of phosphatidylcholine, a component of cell membranes. Citicoline exerts neuroprotective effects.
5-HT6/7 antagonist 1
T61807
5-HT6/7 antagonist 1 is a dual 5-HT6/7/2A and D2 receptor antagonist for the study of dementia and Alzheimer's disease.
DOV-216,303 Free Base
T11087
DOV-216,303 Free Base (DOV-216303) is an inhibitor of serotonin, norepinephrine, and dopamine reuptake with with IC50s of 14, 20 and 78 nM. DOV-216,303 Free Base...
Dexchlorpheniramine Maleate
T0785
Dexchlorpheniramine Maleate (S-(+)-Chlorpheniramine maleate salt) is an antihistamine with anticholinergic properties used to treat allergic conditions such as h...
N-Desmethylclozapine
T5158
N-Desmethylclozapine (Desmethylclozapine) is an antagonist of serotonin (5-HT) receptor subtype 5-HT2C (IC50: 7.1 nM). It also is an antagonist at dopamine D4 re...
Pramipexole
T1476
Pramipexole (SND 919) is a selective dopamine receptor agonist used in the therapy of Parkinson disease. Pramipexole therapy is associated with a low rate of tra...
Spiroxatrine
T23382
Spiroxatrine (R 5188) is a selective and potent 5-HT1α and α2-adrenergic dual antagonist with sedative activity and inhibitory effects on 5-HT1α, 5-HT1 β, 5-HT2,...
Clomipramine hydrochloride
T0255
Clomipramine hydrochloride (Anafranil) is a tricyclic antidepressant similar to IMIPRAMINE that selectively inhibits the uptake of serotonin in the brain. It is ...
ML417
T8423
ML417 is a selective and brain penetrant agonist of D3 Dopamine (EC50 : 38 nM).
Thioridazine hydrochloride
T0365
Thioridazine hydrochloride (Mellaril) , an antipsychotic drug, is used in the therapy of psychosis and schizophrenia and shows serotonin antagonism or D4 selecti...
Escitalopram
T0185
Escitalopram (Seroplex) is a furancarbonitrile that is one of the SEROTONIN UPTAKE INHIBITORS used as an antidepressant. The drug is also effective in reducing e...
L-745870 trihydrochloride
T22904
L-745870 trihydrochloride is a highly potent and selective D4 dopamine receptor antagonist.
Flibanserin
T4297
Flibanserin (Girosa) is a serotonergic antidepressant used to treat hypoactive sexual desire disorder. Flibanserin has been associated with a low rate of minor s...
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