| T38410 |
Phosphoramide mustard
|
10159-53-2
|
98%
|
|
|
Phosphoramide mustard is a toxic metabolite of cyclophosphamide with anticancer activity and ovarian toxicity that induces DNA damage.
|
| T20339 |
7-Hydroxymethotrexate
|
5939-37-7
|
98%
|
|
|
7-Hydroxymethotrexate is the major metabolite of Methotrexate.Methotrexate is an inhibitor of folic acid, inhibiting dihydrofolate reductase, which prevents the ...
|
| T37514 |
Hydroxy Dimetridazole
|
936-05-0
|
98%
|
|
|
Dimetridazole is a nitroimidazole-based compound with antibacterial and anticoccidial activity. It was once widely used in the treatment of parasitic infections ...
|
| T8339 |
16α-Hydroxyprednisolone
|
13951-70-7
|
98%
|
|
|
16α-Hydroxyprednisolone is a stereoselective metabolite of the 22(R) epimer of the glucocorticoid budesonide
|
| T3540 |
IMR-1A
|
331862-41-0
|
|
|
|
IMR-1A is the metabolite of IMR-1 which is a novel class of Notch inhibitors targeting the transcriptional activation with IC50 of 6 μMol/L.
|
| T12095 |
Monomethyl fumarate
|
2756-87-8
|
|
|
|
Monomethyl fumarate is a potent agonist of GPR109A .
|
| T11039 |
Didesethyl chloroquine
|
4298-14-0
|
100%
|
|
|
Didesethyl chloroquine (Bisdesethylchloroquine) is an effective myocardial inhibitor. Didesethyl chloroquine (Bisdesethylchloroquine) is the main metabolite of t...
|
| T77551 |
6'-hydroxydihydrocinchonidine
|
5962-19-6
|
100%
|
|
|
6'-hydroxydihydrocinchonidine is a metabolite of quinine, with antimicrobial and antitumor activity, and inhibitory effect on Trypanosoma brucei and Streptococc...
|
| TN7246 |
3-Sulfopropanoic acid
|
44826-45-1
|
100%
|
|
|
3-Sulfopropanoic acid, a major metabolite of treprostinil and its prodrug ALZ-801, is an endogenous molecule present in the cerebrospinal fluid (CSF) of AD patie...
|
| T24047 |
Etilevodopa hydrochloride
|
39740-30-2
|
95.00%
|
|
|
Etilevodopa hydrochloride (L-DOPA ethyl ester) is a prodrug of levodopa. It also has greater gastric solubility and significant brain penetration.
|
| T16045 |
Methotrexate metabolite
|
19741-14-1
|
95.28%
|
|
|
Methotrexate metabolite (DAMPA) (DAMPA) is the active metabolite of Methotrexate. Methotrexate is a folic acid antagonist. Methotrexate is used as a chemotherape...
|
| T10152 |
4-Methylamino antipyrine
|
519-98-2
|
95.85%
|
|
|
4-Methylamino antipyrine is an active metabolite of Metamizole. Metamizole is a pyrazolone non-steroidal anti-inflammatory drug (NSAID) and inhibits COX. 4-Methy...
|
| T18750 |
N-Deshydroxyethyl Dasatinib
|
910297-51-7
|
95.96%
|
|
|
N-Deshydroxyethyl Dasatinib (N-Deshydroxyethyl BMS-354825) is a metabolite of Dasatinib, a dasatinib-based molecule that degrades ABL by binding to the IAP ligan...
|
| T4282 |
S-methyl-KE-298
|
143584-75-2
|
96.90%
|
|
|
S-methyl-KE-298 is the second main metabolite in plasma,is a methyl conjugate of deacetyl-KE-298.KE-298 inhibits matrix metalloproteinase (MMP-1) production from...
|
| T4350 |
Palifosfamide
|
31645-39-3
|
97%
|
|
|
Palifosfamide (Isophosphamide mustard) lysine (ZIO-201) is a stable form of palifosfamide. Palifosfamide lysine has broad activity in sarcoma lines in vitro. The...
|
| T13564 |
AZ7550
|
1421373-99-0
|
97.07%
|
|
|
AZ7550, an active metabolite of AZD9291, inhibits the activity of IGF1R (IC50: 1.6 μM).
|
| T5320 |
Tulipalin A
|
547-65-9
|
98%
|
|
|
Tulipalin A (α-methylene-γ-butyrolactone) (2-Methylenebutyrolactone) which has some phytotoxicity is a natural compound extracted from Tulipa gesneriana.
|
| T7440 |
P,p'-DDE
|
72-55-9
|
98%
|
|
|
p,p'-DDE (p,p'-dichlorodiphenyldichloroethylene) is a metabolite and degradation product of the organochlorine pesticide DDT
|
| T10157 |
Regorafénib N-oxyde (M2)
|
835621-11-9
|
98.03%
|
|
|
Regorafénib N-oxyde M2 is an active metabolite of Regorafenib. Regorafenib is a multi-target inhibitor for VEGFR1/2/3, PDGFRβ, RET, Kit, and Raf-1 (IC50s: 13/4.2...
|
| TN1352 |
N-(3-Methoxybenzyl-(9z,12z)-octadecadienamide
|
883715-22-8
|
98.22%
|
|
|
N-(3-Methoxybenzyl-(9z,12z)-octadecadienamide ((9Z,12Z)-N-(3-Methoxybenzyl)octadeca-9,12-dienamide) is a Macamide impurity that may be used in the study of metab...
|
