Factor Xa

Factor X, also known by the eponym Stuart–Prower factor, is an enzyme of the coagulation cascade. It is a serine endopeptidase (protease group S1, PA clan). Factor X is synthesized in the liver and requires vitamin K for its synthesis.Factor X is activated, by hydrolysis, into factor Xa by both factor IX (with its cofactor, factor VIII in a complex known as intrinsic Tenase) and factor VII with its cofactor, tissue factor (a complex known as extrinsic Tenase ). It is therefore the first member of the final common pathway or thrombin pathway.

Cat. No.	製品名	CAS No.	Purity	Chemical Structure
T77018	Garadacimab	2162134-62-3	98%	Garadacimab
T77018	Garadacimab (CSL312) is a potent whole-human IgG4 monoclonal antibody targeting activation factor XII (FXIIa). Garadacimab can be used to study hereditary angioe...			Garadacimab
T1736	Apixaban	503612-47-3	100%
T1736	Apixaban (BMS-562247-01) is an orally active inhibitor of coagulation factor Xa with anticoagulant activity. Apixaban directly inhibits factor Xa, thereby interf...
T39463	Asundexian	2064121-65-7	100%
T39463	Asundexian (BAY-2433334) is a potent and orally active inhibitor of the coagulation factor FXIa that directly and reversibly binds to the active site of FXIa, th...
T4076	Fondaparinux sodium	114870-03-0	98%
T4076	Fondaparinux sodium (SR-90107A) is an antithrombin-dependent factor Xa inhibitor with antithrombotic activity.
T10174	5-R-Rivaroxaban	865479-71-6	98.3%
T10174	5-R-Rivaroxaban is (R)-enantiomer of Rivaroxaban. Rivaroxaban (BAY 59-7939) is a highly potent and selective, direct Factor Xa (FXa) inhibitor (IC50 0.7 nM; Ki 0...
T78215	Dechloro Rivaroxaban	1415566-28-7	98.63%
T78215	Dechloro Rivaroxaban is an orally active and highly selective Factor Xa inhibitor.Dechloro Rivaroxaban has a significant inhibitory effect on free FXa in humans....
T20454	4-Chlorophenylurea	140-38-5	98.69%
T20454	4-Chlorophenylurea (NSC-12971) is a novel orally bioavailable inhibitor of factor Xa.
T4980	Betrixaban maleate	936539-80-9	98.81%
T4980	Betrixaban maleate is a non-vitamin K oral anticoagulant whose action is driven by the competitive and reversible inhibition of the factor Xa.
T31206	Darexaban	365462-23-3	98.81%
T31206	Darexaban (Tanexaban, YM-150) is a direct inhibitor of Factor Xa.Darexaban and Darexaban glucuronide selectively and competitively inhibit FXA and inhibit prothr...
T68092	Letaxaban	870262-90-1	99.01%
T68092	Letaxaban (TAK-442) is a small molecule Xa factor inhibitor that can be used to study polar coronary syndromes and thrombotic blockages.
T4341	Betrixaban	330942-05-7	99.35%
T4341	Betrixaban (PRT054021) is a non-vitamin K oral anticoagulant whose action is driven by the competitive and reversible inhibition of the factor Xa [1]. It was sel...
T29215	Zifaxaban	1378266-98-8	99.42%
T29215	Zifaxaban (TY-602) is an orally active, competitive and selective inhibitor of factor Xa (FXa) with an IC50 of 11.1 nM for human FXa.Zifaxaban has a very high af...
T27318	Fidexaban	183305-24-0	99.42%
T27318	Fidexaban (CI1031) is a novel, potent, selective and orally active factor Xa inhibitor that has demonstrated antithrombotic activity in a variety of assays
T4690	Betrixaban hydrochloride(330942-05-7(free base))	T4690	99.54%
T4690	Betrixaban hydrochloride(330942-05-7(free base)) (PRT054021 hydrochloride) is a potent, selective, and orally efficacious factor Xa (fXa) inhibitor (IC50: 1.5 nM...
T66256	Ethyl 1-(4-methoxyphenyl)-7-oxo-6-(4-(2-oxopiperidin-1-yl)phenyl)-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylate	503614-91-3	99.55%
T66256	Ethyl 1-(4-methoxyphenyl)-7-oxo-6-(4-(2-oxopiperidin-1-yl)phenyl)-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylate has an inhibitory effect on coagula...
T0642	2-Methoxyphenothiazine	1771-18-2	99.56%
T0642	2-Methoxy Phenothiazine is light yellow or light gray solid.
T2368L	Edoxaban	480449-70-5	99.6%
T2368L	Edoxaban (Lixiana) (DU-176) is a selective, potent and orally active factor Xa (FXa) inhibitor with K i s of 0.561 nM and 2.98 nM for free FXa and prothrombinase...
T67853	Rivaroxaban Impurity	1151893-81-0	99.61%
T67853	Rivaroxaban Impurity (Rivaroxaban-10) is a potent Blood-coagulation factor Xa inhibitor, IC50= 66 nM.
T0372	Gabexate mesylate	56974-61-9	99.64%
T0372	Gabexate mesylate (FOY) is a serine proteinase inhibitor used therapeutically in the treatment of pancreatitis, disseminated intravascular coagulation (DIC), and...
T1184	Rivaroxaban	366789-02-8	99.69%
T1184	Rivaroxaban (BAY 59-7939) is an orally bioavailable oxazolidinone derivative and direct inhibitor of the coagulation factor Xa with anticoagulant activity. Upon ...