| T14298 |
Rimiducid
|
195514-63-7
|
98%
|
|
|
Rimiducid is a lipid-permeable tacrolimus analogue, homodimerizing an analogue of human protein fkbp12 and binding to wild-type fkbp12 with 1000-fold lower affin...
|
| T27307L |
Fasnall HCl
|
|
98%
|
|
|
Fasnall HCl is a selective FASN inhibitor that acts through its co-factor binding sites. Fasnall HCl also shows potent anti-tumor activity in the MMTV-Neu model ...
|
| T6832 |
Fatostatin hydrobromide
|
298197-04-3
|
98%
|
|
|
Fatostatin hydrobromide (Fatostatin A HBr) ia an inhibitor of sterol regulatory element binding protein (SREBP). It impairs the activation of SREBP-1 and SREBP-2...
|
| T36841 |
IPI-9119
|
1346564-56-4
|
98%
|
|
|
IPI-9119 is an orally active, selective and irreversible FASN inhibitor (IC50 = 0.3 nM).
|
| T21724L |
Fas C-Terminal Tripeptide Acetate
|
T21724L
|
|
|
|
Fas C-Terminal Tripeptide Acetate shows inhibitory activity of Fas/FAP-1 binding.
|
| TQ0260 |
Cerulenin
|
17397-89-6
|
|
|
|
Cerulenin is a natural inhibitor of fatty acid synthase (FAS). It is produced by the fungus Cephalosporium caeruleus.
|
| T3121 |
Betulin
|
473-98-3
|
|
|
|
Betulin (betulinol) (lup-20(29)-ene-3β, 28-diol) is an abundant, naturally occurring triterpene. It is commonly isolated from the bark of birch trees where it fo...
|
| T27307 |
Fasnall
|
929978-58-5
|
|
|
|
Fasnall is a selective FASN inhibitor that acts through its co-factor binding sites. Fasnall shows potent anti-tumor activity in the MMTV-Neu model of HER2(+) br...
|
| T3S1701 |
Dihydrocurcumin
|
76474-56-1
|
97.23%
|
|
|
Dihydrocurcumin is the main metabolite of curcumin, which can reduce fat accumulation and oxidative stress response. Dihydrocurcumin can regulate the mRNA and pr...
|
| T7947 |
FT113
|
1630808-89-7
|
97.68%
|
|
|
FT113 is a novel potent inhibitor of fatty acid synthase (fasn, IC50 : 213 nM),and exhibits anti-cancer activity
|
| TN1803 |
Isoscoparin
|
20013-23-4
|
97.95%
|
|
|
Isoscoparin is derived from Gentiana algida Pall with antioxidant and anti-adipogenic activities. Isoscoparin can be used in stuides about the prevention and tre...
|
| T5S0246 |
Pseudoprotodioscin
|
102115-79-7
|
98%
|
|
|
1. Pseudoprotodioscin has moderate cytotoxicity.
|
| T11557 |
FASN-IN-3
|
2097262-60-5
|
98.22%
|
|
|
FASN-IN-3 is an inhibitor of fatty acid synthase (FASN).
|
| T11267 |
FASN-IN-1
|
1808260-84-5
|
98.23%
|
|
|
FASN-in-1 is an effective, specific inhibitor of fatty acid synthase (FASN), a compound specifically designed to target and inhibit the activity of the enzyme in...
|
| T9732 |
VY-3-135
|
1824637-41-3
|
98.56%
|
|
|
VY-3-135 is a metastasis inhibitor and an acetyl-CoA synthetase 2 (ACSS2) modulator.
|
| T3324 |
Lycorine
|
476-28-8
|
98.71%
|
|
|
Lycorine (Narcissine) inhibits protein synthesis and may inhibit ascorbic acid biosynthesis, although studies on the latter are controversial and inconclusive.
|
| T2468 |
A-769662
|
844499-71-4
|
98.72%
|
|
|
A-769662 is an effective, reversible AMPK activator(EC50=0.8 μM).
|
| T10656 |
Trans-C75
|
191282-48-1
|
98.79%
|
|
|
trans-C75 ((±)-C75) is an enantiomer of C75. C75 is an inhibitor of fatty-acid synthase (FASN).
|
| T10657 |
C75
|
218137-86-1
|
98.84%
|
|
|
C75 is an inhibitor synthetic fatty-acid synthase (FASN) and inhibits prostate cancer cells PC3 (IC50: 35 μM).
|
| T7798 |
FGH10019
|
1046045-61-7
|
98.93%
|
|
|
FGH10019 is a novel inhibitor of sterol regulatory element-binding protein (SREBP) ( IC50 :1 μM).
|
