| T1934 |
Bay 11-7085
|
196309-76-9
|
98%
|
|
|
Bay 11-7085 can irreversibly inhibit the IκBα phosphorylation induced by TNFα (IC50: 10 μM).
|
| T60084 |
FINO2
|
869298-31-7
|
98%
|
|
|
FINO2 is a potent ferroptosis-inducing compound that inhibits GPX4 activity. It functions as a stable oxidant, effectively oxidizing ferrous iron and demonstrati...
|
| T6821 |
Dp44mT
|
152095-12-0
|
98%
|
|
|
Dp44mT, a effective iron chelator, has selective antitumor activity.
|
| T5523 |
Imidazole ketone erastin
|
1801530-11-9
|
98%
|
|
|
Imidazole ketone erastin (IKE) is an iron death inducer with inhibitory effects on system Xc-cystine/glutamate transporter proteins. Imidazole ketone erastin has...
|
| T0078L |
Lapatinib ditosylate monohydrate
|
388082-78-8
|
|
|
|
Lapatinib ditosylate (Lapatinib tosilate) monohydrate is a tyrosine kinase receptor inhibitor used in the therapy of advanced breast cancer and other solid tumor...
|
| T6871 |
L-Glutamic acid monosodium salt
|
142-47-2
|
|
|
|
L-Glutamic acid monosodium salt (MSG) (Monosodium glutamate) is an activator of mGlu1 receptor.
|
| T20819 |
Ammonium iron(III) citrate
|
1185-57-5
|
|
|
|
Ammonium iron(III) citrate (Ferric ammonium citrate) is a physiological form of non-ferritin-bound iron that causes intracellular iron overload leading to cellul...
|
| T2887 |
Trigonelline
|
535-83-1
|
|
|
|
Trigonelline (Trigenolline), an alkaloid with potential antidiabetic activity, is present in considerable amounts in coffee.
|
| T1885 |
Siramesine hydrochloride
|
224177-60-0
|
|
|
|
Siramesine hydrochloride (Lu 28-179 hydrochloride) is a selective sigma-2 receptor agonist, which has been shown to trigger cell death of Y cells and to exhibit ...
|
| T0326 |
DL-Glutamine
|
6899-04-3
|
|
|
|
DL-Glutamine (2-amino-4-carbamoylbutanoic acid), a non-essential amino acid, exists abundantly throughout the body and is participated in many metabolic processe...
|
| T7708 |
DL-Buthionine-(S,R)-sulfoximine
|
5072-26-4
|
|
|
|
DL-Buthionine-(S,R)-sulfoximine (Butionine sulfoximine) is an inhibitor of γ-glutamylcysteine synthetase for the treatment of solid tumors.
|
| T6954 |
PRIMA-1
|
5608-24-2
|
|
|
|
PRIMA-1 (NSC-281668) is a mutant p53 reactivator. It induces apoptosis and inhibits growth of human tumors with mutant p53.
|
| T1847 |
Necrostatin-1
|
4311-88-0
|
100%
|
|
|
Necrostatin-1 (Nec-1) is a necrotic apoptosis inhibitor and RIP1 inhibitor with specificity. Necrostatin-1 inhibits TNF-α-induced necrotic apoptosis. Necrostatin...
|
| T0935 |
Butylated hydroxytoluene
|
128-37-0
|
100%
|
|
|
Butylated hydroxytoluene (BHT FCC/NF) is an antioxidant widely used in food, cosmetics and industrial liquids. It is a ferroptosis inhibitor.
|
| T2870 |
Matrine
|
519-02-8
|
100%
|
|
|
Matrine (Vegard), an alkaloid isolated from the Sophora genus, acts as a kappa opioid receptor agonist.
|
| T0392 |
Artemisinin
|
63968-64-9
|
97%
|
|
|
Artemisinin (Qinghaosu) is an ancient Chinese herbal therapy for malarial fevers which has been recently found to have potent activity against many forms of mala...
|
| T8375 |
ML-210
|
1360705-96-9
|
97%
|
|
|
ML-210 (CID 49766530) is a selective RAS and covalent glutathione peroxidase 4 (GPX4) inhibitor(GPX4, EC50 : 30 nM), with anti-cancer activity
|
| T2858 |
Baicalein
|
491-67-8
|
97.25%
|
|
|
Baicalein (5,6,7-Trihydroxyflavone) is a xanthine oxidase inhibitor.
|
| TJS1159 |
Chrysosplenetin
|
603-56-5
|
97.43%
|
|
|
Chrysosplenetin is a metabolic inhibitor of artemisinin.
|
| T16540 |
Piperazine Erastin
|
1538593-71-3
|
97.74%
|
|
|
Piperazine erastin is an analog of erastin. It causes an iron-dependent form of non-apoptotic cell death termed ferroptosis.
|
