| T11661 |
INT-767
|
1000403-03-1
|
98%
|
|
|
INT-767 is a potent farnesoid X receptor (FXR)/TGR5 dual agonist that prevents NASH and promotes visceral adipose brown lipogenesis and mitochondrial function fo...
|
| T2968 |
Hyodeoxycholic acid
|
83-49-8
|
97.26%
|
|
|
Hyodeoxycholic acid (NSC 60672) has been used in trials studying the treatment of Hypercholesterolemia.
|
| T1824 |
TGR5 Receptor Agonist
|
1197300-24-5
|
98%
|
|
|
TGR5 is a potent TGR5(GPCR19) agonist.
|
| T8818 |
TC-G 1005
|
1415407-60-1
|
98.2%
|
|
|
TC-G 1005 is a potent and selective GPBA agonist (EC50 :0.72 nM; hTGR5). Selective for TGR5 over FXR (farnesoid X receptor). Increases plasma GLP-1 levels and re...
|
| T4352 |
SB756050
|
447410-57-3
|
98.35%
|
|
|
SB756050 is a specific TGR5 agonist.
|
| T29078 |
Ursodeoxycholic acid sodium
|
2898-95-5
|
98.55%
|
|
|
Ursodeoxycholic acid sodium (Sodium Ursodeoxycholate) is a naturally occurring secondary bile acid with anti-inflammatory and cytoprotective activities. Ursodeox...
|
| TP1949L |
PEN (human) aceate
|
|
99.25%
|
|
|
PEN (human) aceate, one of the most abundant hypothalamic neuropeptide and derived from the proprotein ProSAAS, is an endogenous ligand of GPR83.
|
| T4083 |
BAR501
|
1632118-69-4
|
99.34%
|
|
|
BAR501 is an effective and specific GPBAR1 agonist (EC50: 1 μM).
|
| T2965 |
Deoxycholic acid
|
83-44-3
|
99.35%
|
|
|
Deoxycholic acid (Cholanoic Acid) is a bile acid formed by bacterial action from cholate. It is usually conjugated with glycine or taurine. Deoxycholic acid acts...
|
| T7428 |
SBI-115
|
882366-16-7
|
99.67%
|
|
|
SBI-115 is an antagonist of TGR5. SBI-115 decreases hepatic cystogenesis with polycystic liver diseases via inhibiting TGR5
|
| T5077 |
Deoxycholic acid sodium salt
|
302-95-4
|
99.75%
|
|
|
Deoxycholic acid sodium salt (Sodium deoxycholate) can activate the G protein-coupled bile acid receptor TGR5 that stimulates brown adipose tissue (BAT) thermoge...
|
| T11662L |
INT-777
|
1199796-29-6
|
99.89%
|
|
|
INT-777 (S-EMCA) is a potent TGR5 agonist with an EC50 of 0.82 μM. INT-777 (S-EMCA) inhibits NLRP5-ASC inflammasome-mediated neuroinflammation via the TGR3/cAMP/...
|
| TQ0252 |
BAR502
|
1612191-86-2
|
99.91%
|
|
|
BAR502 is a dual GPBAR1 and FXR agonist (IC50s: 0.4 μM and 2 μM).
|
| T8752 |
BAR 501 impurity
|
1632118-70-7
|
99.97%
|
|
|
BAR501 impurity is an impurity found in the preparation of BAR501 that acts as an agonist of the G protein-coupled bile acid-activated receptor (GP-BAR1). BAR501...
|
| T11798 |
L-692429
|
145455-23-8
|
99.9%
|
|
|
L-692429 (MK-0751) is a potent nonpeptidyl growth hormone secretagogue (GHS) agonist, a benzolactam derivative, which reverses the inhibition of GH secretion by ...
|
