| T5142 |
NAV-2729
|
419547-11-8
|
98%
|
|
|
NAV-2729 inhibits six ArfGEFs (human ARNO, EFA6, BIG1, and BRAG2 and Legionella and Rickettsia RalF), the strongest effects being against BRAG2, Arf1 and Arf6.
|
| T14898 |
CCG-63808
|
620113-73-7
|
98%
|
|
|
CCG-63808 is a reversible inhibitor of regulator of G-protein signaling (RGS) proteins. CCG-63808 dose-dependently inhibits the TR-FRET signal between RGS4-AF488...
|
| T14897 |
CCG-63802
|
620112-78-9
|
98%
|
|
|
CCG-63802 is a reversible inhibitor of the regulator of G-protein signaling (RGS) protein and has the greatest potency at RGS4.
|
| T34973 |
Tyrphostin 8
|
3785-90-8
|
98%
|
|
|
Tyrphostin 8(4-Hydroxybenzylidenemalononitrile) is a potent GTPase inhibitor that inhibits EGFR kinase with an IC50 of 560 μM.Tyrphostin 8 inhibits protein serin...
|
| T24706 |
RBC10
|
362503-73-9
|
98%
|
|
|
RBC10 inhibits the binding of Ral to its effector RALBP1, as well as inhibiting Ral-mediated cell spreading of murine embryonic fibroblasts and anchorage-indepen...
|
| T21798L |
Dynamin inhibitory peptide Acetate
|
T21798L
|
97.28%
|
|
|
Dynamin inhibitory peptide Acetate is a peptide with the sequence Gln-Val-Pro-Ser-Arg-Pro-Asn-Arg-Ala-Pro that inhibit the GTPase dynamin.
|
| T71740 |
CID-4785700
|
852935-07-0
|
98.19%
|
|
|
CID-4785700 is a potent pan-GTPase inhibitor that inhibits Rab7 and inhibits the fungal histone acetyltransferase Rtt109 that binds to Asf1 and Vps75, and can be...
|
| T21970 |
ML-097
|
743456-83-9
|
98.21%
|
|
|
ML-097 (CID-2160985) is a pan activator of Ras-related GTPases
|
| T2267 |
BQU57
|
1637739-82-2
|
98.36%
|
|
|
BQU57 shows selective inhibition for Ral relative to Ras or Rho and inhibit xenograft tumor growth.
|
| T4022 |
QS11
|
944328-88-5
|
98.39%
|
|
|
QS11 is a GTPase activating protein of ADP-ribosylation factor 1 (ARFGAP1) inhibitor. Modulates ARF-GTP levels and synergizes with the Wnt/β-catenin signaling pa...
|
| T6434 |
CCG-50014
|
883050-24-6
|
98.69%
|
|
|
CCG-50014 is a potent and selective inhibitor of RGS4 with IC50 of 30 nM.
|
| T25529 |
IMM-01
|
218795-74-5
|
98.81%
|
|
|
IMM-01 is a novel class of small-molecule agonists of the mammalian Diaphanous (mDia)-related formins, which act downstream of Rho GTPases to assemble actin fila...
|
| T10705 |
CCG 203769
|
410074-60-1
|
99.46%
|
|
|
CCG 203769 (Thiadiazolidinone (TDZD) deriv. 6) is a selective inhibitor of RGS4 with an IC50 of 17 nM for the RGS4-Gαo protein-protein interaction.
|
| T9200 |
Exo-1
|
461681-88-9
|
99.74%
|
|
|
Exo-1 (Methyl 3-(4-fluorobenzoyl)-6-methyl-2-pyridinecarboxylate) is a synthetic compound that has been shown to affect the metabolism of various nutrients, as w...
|
| T38387 |
Compound C108
|
15533-09-2
|
99.77%
|
|
|
Compound C108 is an inhibitor of GTPase-activating protein SH3 domain-binding protein 2 (G3BP2). Compound C108 can be used in studies about breast tumors and eso...
|
| T6634 |
RBC8
|
361185-42-4
|
99.81%
|
|
|
RBC8 is a specific GTPases RalA/RalB inhibitor by inhibiting the binding of Ral to its effector RALBP1, no inhibition on the GTPases RhoA and Ras.
|
| TN4098 |
Gancaonin I
|
126716-36-7
|
98%
|
|
|
Gancaonin I exhibits anti-BsFtsZ GTPase activities; it also shows significant inhibitory activity against B. subtilis, with a MIC value of 5 uM.
|
