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GluR

Glutamate receptors are synaptic and non synaptic receptors located primarily on the membranes of neuronal and glial cells.Glutamate receptors are responsible for the glutamate-mediated postsynaptic excitation of neural cells, and are important for neural communication, memory formation, learning, and regulation.
Cat. No. 製品名 CAS No. Purity Chemical Structure
T65135 Kynurenic acid 492-27-3 98%
Kynurenic acid (Quinurenic acid) is an endogenous tryptophan active metabolite, a triple antagonist of NMDA, glutamate, α7 nicotinic acetylcholine receptor, and ...
T4500 ADX88178 1235318-89-4 98%
ADX88178 is a potent positive allosteric modulator for metabotropic glutamate receptor 4 (mGluR4) with EC50 of 4 nM for human mGluR4.
T3010 Xanthurenic Acid 59-00-7 98%
Xanthurenic Acid (8-Hydroxykynurenic acid), a molecule arising from tryptophan metabolism by transamination of 3-hydroxykynurenine, activates mGlu2/3 Metabotropi...
T15619 JNJ-46778212 1363281-27-9 98%
JNJ-46778212 is an effective mGlu5 allosteric modulator (EC50: 260 nM).
T3957 Farampator 211735-76-1 98%
Farampator (CX-691) (CX-691;Org24448) is a positive modulator of AMPA receptor.
T6871 L-Glutamic acid monosodium salt 142-47-2 98%
L-Glutamic acid monosodium salt (MSG) (Monosodium glutamate) is an activator of mGlu1 receptor.
T15819 LY377604 204592-94-9 98%
LY377604 is a human β3-adrenergic receptor agonist (EC50: 2.4 nM). It also a β1- and β2-adrenergic receptor antagonist.
T9011 VU0155094 731006-86-3 98%
VU0155094 (ML 397) is a positive allosteric modulator with differential activity at the various group III mGluRs.
T20191 (-)-Camphoric acid 560-09-8 98%
(-)-Camphoric acid (L-Camphoric acid) is a less active enantiomer of Camphoric acid which induces GluR expression.
T20571 Cis-PDA 46026-75-9 98%
cis-PDA (cis PDA) is a general ionotropic receptor antagonist. cis-PDA acts by blocking NMDA, AMPA, and kainate-mediated responses.
T13323 VU6012962 2313526-86-0 98%
VU6012962 is an orally bioavailable negative allosteric modulator of CNS-penetrant metabotropic glutamate receptor 7(mGlu7; IC50: 347 nM).
T6562 Latrepirdine dihydrochloride 97657-92-6 98%
Latrepirdine dihydrochloride (Dimebolin dihydrochloride) is an orally active, and neuroactive antagonist of multiple drug targets, including histamine receptors,...
T22638 CBiPES hydrochloride 856702-40-4 98%
CBiPES hydrochloride (CBiPES HCl) is a potent orthosteric modulator of the mGlu2 receptor with an EC50 value of 92.8 nM.CBiPES hydrochloride blocks the action of...
T9133 Caroverine hydrochloride 55750-05-5 98%
Caroverine hydrochloride (Caroverine HCL) is a potent, competitive and reversible antagonist of NMDA and AMPA glutamate receptor. It is also an antioxidant and c...
T22840 HexylHIBO 334887-43-3 98%
HexylHIBO is a type I mGluR antagonist that inhibits mGlu1a and mGlu5a, with Kb values of 140 and 110 μM, respectively.HexylHIBO decreases sEPSC in rats.
T1443 Memantine hydrochloride 41100-52-1 98%
Memantine hydrochloride (Memantine HCl) is an AMANTADINE derivative that has some dopaminergic effects. Memantine hydrochloride has been proposed as an antiparki...
T3479 (RS)-MCPG 146669-29-6 98%
(RS)-MCPG ((±)-MCPG) is a non-selective group I/II metabotropic glutamate receptor antagonist.
T22711 DCB 6971-97-7 98%
DCB (3,3'-dichlorobenzaldazine) is an allosteric ligand for mGluR5 and shows the negative modulatory effect of 3,3′-dimethoxybenzaldazine (DMeOB). DCB blocks the...
T3473 (S)-ATPO 252930-37-3 98%
(S)-ATPO is Competitive antagonist at GluR1-4 (AMPA-preferring) receptors.
T15456 GYKI 53655 hydrochloride 143692-48-2 98%
GYKI 53655 hydrochloride (LY300168 hydrochloride) is an antagonist of AMPA and is used in the study of neurological disorders.
Kynurenic acid
T65135
Kynurenic acid (Quinurenic acid) is an endogenous tryptophan active metabolite, a triple antagonist of NMDA, glutamate, α7 nicotinic acetylcholine receptor, and ...
ADX88178
T4500
ADX88178 is a potent positive allosteric modulator for metabotropic glutamate receptor 4 (mGluR4) with EC50 of 4 nM for human mGluR4.
Xanthurenic Acid
T3010
Xanthurenic Acid (8-Hydroxykynurenic acid), a molecule arising from tryptophan metabolism by transamination of 3-hydroxykynurenine, activates mGlu2/3 Metabotropi...
JNJ-46778212
T15619
JNJ-46778212 is an effective mGlu5 allosteric modulator (EC50: 260 nM).
Farampator
T3957
Farampator (CX-691) (CX-691;Org24448) is a positive modulator of AMPA receptor.
L-Glutamic acid monosodium salt
T6871
L-Glutamic acid monosodium salt (MSG) (Monosodium glutamate) is an activator of mGlu1 receptor.
LY377604
T15819
LY377604 is a human β3-adrenergic receptor agonist (EC50: 2.4 nM). It also a β1- and β2-adrenergic receptor antagonist.
VU0155094
T9011
VU0155094 (ML 397) is a positive allosteric modulator with differential activity at the various group III mGluRs.
(-)-Camphoric acid
T20191
(-)-Camphoric acid (L-Camphoric acid) is a less active enantiomer of Camphoric acid which induces GluR expression.
cis-PDA
T20571
cis-PDA (cis PDA) is a general ionotropic receptor antagonist. cis-PDA acts by blocking NMDA, AMPA, and kainate-mediated responses.
VU6012962
T13323
VU6012962 is an orally bioavailable negative allosteric modulator of CNS-penetrant metabotropic glutamate receptor 7(mGlu7; IC50: 347 nM).
Latrepirdine dihydrochloride
T6562
Latrepirdine dihydrochloride (Dimebolin dihydrochloride) is an orally active, and neuroactive antagonist of multiple drug targets, including histamine receptors,...
CBiPES hydrochloride
T22638
CBiPES hydrochloride (CBiPES HCl) is a potent orthosteric modulator of the mGlu2 receptor with an EC50 value of 92.8 nM.CBiPES hydrochloride blocks the action of...
Caroverine hydrochloride
T9133
Caroverine hydrochloride (Caroverine HCL) is a potent, competitive and reversible antagonist of NMDA and AMPA glutamate receptor. It is also an antioxidant and c...
HexylHIBO
T22840
HexylHIBO is a type I mGluR antagonist that inhibits mGlu1a and mGlu5a, with Kb values of 140 and 110 μM, respectively.HexylHIBO decreases sEPSC in rats.
Memantine hydrochloride
T1443
Memantine hydrochloride (Memantine HCl) is an AMANTADINE derivative that has some dopaminergic effects. Memantine hydrochloride has been proposed as an antiparki...
(RS)-MCPG
T3479
(RS)-MCPG ((±)-MCPG) is a non-selective group I/II metabotropic glutamate receptor antagonist.
DCB
T22711
DCB (3,3'-dichlorobenzaldazine) is an allosteric ligand for mGluR5 and shows the negative modulatory effect of 3,3′-dimethoxybenzaldazine (DMeOB). DCB blocks the...
(S)-ATPO
T3473
(S)-ATPO is Competitive antagonist at GluR1-4 (AMPA-preferring) receptors.
GYKI 53655 hydrochloride
T15456
GYKI 53655 hydrochloride (LY300168 hydrochloride) is an antagonist of AMPA and is used in the study of neurological disorders.
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