Glucagon Receptor

The glucagon receptor is a 62 kDa protein that is activated by glucagon and is a member of the class B G-protein coupled family of receptors, coupled to G alpha i, Gs and to a lesser extent G alpha q. Stimulation of the receptor results in activation of adenylate cyclase and increased levels of intracellular cAMP. In humans, the glucagon receptor is encoded by the GCGR gene.

Cat. No.	製品名	CAS No.	Purity
T14130	Adomeglivant	1488363-78-5	98%
T14130	Adomeglivant (LY2409021) is a potent and selective glucagon receptor antagonist. Which is used in clinical trial for type 2 diabetes mellitus.
T9579L	GLP-1 receptor agonist 9 citrate	T9579L	98%
T9579L	GLP-1 receptor agonist 9 citrate is an agonist of GLP-1.
T61483	GLP-1R modulator C5	421578-93-0	98%
T61483	GLP-1R modulator C5 is a small molecule GLP-1R orthosteric modulator that enhances GLP-1 binding to GLP-1R via transmembrane sites and can be used in the study o...
T19117	3-Deoxyglucosone	4084-27-9	98%
T19117	3-Deoxyglucosone(3-Deoxy-D-glucosone) is synthesized by the intermediate pathway of the melad and polyol reactions.3-Deoxyglucosone reacts rapidly with protein a...
T9579	GLP-1 receptor agonist 9	2401892-71-3	98%
T9579	1H-Benzimidazole-6-carboxylic acid is a GLP-1 receptor agonist.
T15387	GLP-1R Antagonist 1	488097-06-9	98%
T15387	GLP-1R Antagonist 1 is an orally active, CNS penetrant and non-competitive glucagon-like peptide 1 receptor (GLP-1R) antagonist (IC50: 650 nM).
TP2100	Avexitide	133514-43-9	98%
TP2100	Avexitide (Exendin-3 (9-39) amide) (Exendin (9-39)) is a specific and competitive antagonist of glucagon-like peptide-1 (GLP-1) receptor.
T35337L	Teduglutide acetate		98%
T35337L	Teduglutide acetate, a GLP-2 analogue, maximizes small intestinal mucosal hypertrophy. Teduglutide acetate partially restores small intestinal epithelial functio...
T40279	GLP-1R modulator L7-028	2648317-95-5	98%
T40279	GLP-1R modulator L7-028 is a variant modulator that enhances affinity for GLP-1 and cAMP signaling.
T40997	GLP-1R modulator C16	875005-43-9	98%
T40997	GLP-1R modulator C16 is a variable modulator that significantly increases the binding affinity of GLP-4.
TP1976L	Oxyntomodulin acetate		98%
TP1976L	Oxyntomodulin acetate, a 37-amino acid peptide hormone, is a glucagon-like peptide 1 (GLP-1) receptor agonist[1].
TP1111	Tirzepatide	2023788-19-2	98%
TP1111	Tirzepatide (LY-3298176) is a dual agonist of glucose-dependent polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptor with neuroprotective activity for ...
TP2252	GLP-1 (9-36) amide	161748-29-4	98%
TP2252	antagonist at the human GLP-1 receptor
TP1039	Secretin (33-59), rat	121028-49-7	98%
TP1039	Secretin (33-59), rat (Secretin (rat)) is a classical hormone in the gastrointestinal system and a neuropeptide.
TP1863L	Glucagon (19-29), human acetate	TP1863L	98%
TP1863L	Glucagon (19-29), human acetate a COOH-terminal fragment processed from glucagon, is a potent and efficient inhibitor of insulin secretion.
T37890L	GLP-1(28-36)amide acetate	T37890L	98%
T37890L	GLP-1(28-36)amide acetate inhibits mitochondrial permeability transition with antioxidant, anti-diabetic and cardioprotection activities.
T63909	GLP-1R agonist 3	2428640-18-8	98%
T63909	GLP-1R agonist 3 is a thickened imidazole derivative compound that is a potent agonist of GLP-1R. GLP-1R agonist 3 has shown research potential in diabetes.
T78097L	Mazdutide acetate（2259884-03-0 free base）		98%
T78097L	Mazdutide acetate is a potent co-agonist of glucagon-like peptide (GLP-1R) and glucagon receptor (GCGR), a gastrin-regulating hormone analog.Mazdutide acetate st...
TP1111L1	Tirzepatide sodium salt		98%
TP1111L1	Tirzepatide sodium salt (LY3298176 sodium salt) is a GIP and GLP-1 receptor agonist with neuroprotective activity and can be used to treat obesity.
TP2100L	Avexitide acetate	2051593-46-3	98%
TP2100L	Avexitide acetate (exendin 9-39) is a potent glucagon-like peptide 1 receptor (GLP-1R) antagonist for the study of post-obesity hypoglycemia.