| T9833 |
Opiranserin hydrochloride
|
1440796-75-7
|
98%
|
|
|
Opiranserin (VVZ-149) hydrochloride is a dual antagonist of glycine transporter type 2 (GlyT2) and serotonin receptor 2A (5HT2A), with IC50s of 0.86 and 1.3 μM, ...
|
| T6975 |
Sarcosine
|
107-97-1
|
98%
|
|
|
Sarcosine (Methylglycine) is a competitive inhibitor of the type I glycine transporter (GlyT1) and an N-methyl-D-aspartate receptor (NMDAR) co-agonist.
|
| T6788 |
Bitopertin
|
845614-11-1
|
100%
|
|
|
Bitopertin (Paliflutine) (RG1678, RO-4917838) is a potent inhibitor of glycine transporter 1 (GlyT1), with Ki of 8.1 nM for human hGlyT1b and IC50 of 22-25 nM in...
|
| T1568 |
Amoxapine
|
14028-44-5
|
98.25%
|
|
|
Amoxapine (CL-67772) exerts its antidepressant effect by inhibiting the re-uptake of norepinephrine and, to a lesser degree, of serotonin, at adrenergic nerve en...
|
| T22126 |
Org 25543 hydrochloride
|
495076-64-7
|
99.34%
|
|
|
Org 25543 hydrochloride is a potent and selective glycine transporter type 2 (GlyT2) inhibitor (IC50 = 16 nM for hGlyT2). Displays no activity at GlyT1 or 56 oth...
|
| T11908 |
LY2365109 hydrochloride
|
1779796-27-8
|
99.47%
|
|
|
LY2365109 hydrochloride is a potent and selective GlyT1 inhibitor, with an IC50 of 15.8 nM for glycine uptake in cells over-expressing hGlyT1a.
|
| T14198 |
ALX-1393
|
949164-09-4
|
99.73%
|
|
|
ALX-1393 is a selective GlyT2 inhibitor that effectively reduces neuronal action potential activity in a concentration-dependent manner and inhibits the activity...
|
| T61564 |
PF-03463275
|
1173239-39-8
|
99.86%
|
|
|
PF-03463275 is an orally active and selective reversible inhibitor of competitive glycine transporter protein-1 (GlyT1) with a Ki of 11.6 nM.PF-03463275 has CNS ...
|
| T16399 |
Opiranserin
|
1441000-45-8
|
98%
|
|
|
Opiranserin is a development as an injectable agent for the treatment of postoperative pain. Opiranserin is a non-opioid and non-NSAID analgesic candidate and is...
|
| T10552 |
Bitopertin (R enantiomer)
|
845614-12-2
|
98%
|
|
|
Bitopertin R enantiomer (RG1678 R enantiomer) is the R-enantiomer of Bitopertin. Bitopertin is a noncompetitive glycine reuptake inhibitor and inhibits glycine u...
|
| T17096 |
Tilapertin
|
1000690-85-6
|
98%
|
|
|
Tilapertin is an oral glycine transporter type-1 inhibitor.
|
| T14334 |
ASP2535
|
374886-51-8
|
98%
|
|
|
ASP2535 is a potent, selective, orally bioavailable, brain permeable and centrally-active glycine transporter-1 (GlyT1) inhibitor.ASP2535 can improve cognitive i...
|
