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HCV Protease

NS2-3 protease (of hepatitis C virus, HCV) is an enzyme responsible for proteolytic cleavage between NS2 and NS3, which are non-structural proteins that form part of the HCV virus particle. NS3 protease of hepatitis C virus, on the other hand, is responsible for the cleavage of non-structural protein downstream. Both of these proteases are directly involved in HCV genome replication, that is, during the viral life-cycle that leads to virus multiplication in the host that has been infected by the virus.
Cat. No. 製品名 CAS No. Purity Chemical Structure
T9567 Samatasvir 1312547-19-5 98%
Samatasvir (ATOLIHZIXHZSBA-BTSKBWHGSA-N) is a pan-genotypic inhibitor of the HCV non-structural protein 5A.
T16710 Mericitabine 940908-79-2 98%
Mericitabine (R-7128) is a nucleoside HCV NS5B polymerase inhibitor. It acts as an RNA chain terminator and prevents the elongation of RNA transcripts during rep...
T3444 Merimepodib 198821-22-6 98%
Merimepodib (VX-497) is a novel noncompetitive inhibitor of Inosine monophosphate dehydrogenase(IMPDH).
T38375 Pseudane IX 55396-45-7 98%
Pseudane IX (2-nonyl-1H-quinolin-4-one) reduces infection of Huh 7.5 cells by hepatitis C virus (HCV) with an IC50 of 1.4 μg/ml.
T2117 PSI-6206 863329-66-2 98%
PSI-6206 (RO 2433) (RO2433) is a selective HCV RNA polymerase inhibitor.
T11281L FGI-106 tetrahydrochloride 1149348-10-6 98%
FGI-106 tetrahydrochloride is active against Ebola, Rift Valley and Dengue Fever viruses with EC50s of 100 nM, 800 nM and 400-900 nM, respectively. FGI-106 tetra...
T24178 Isatoribine 122970-40-5 98%
Isatoribine(ANA245) free base is a potent TLR7 receptor agonist with anti-hepatitis C virus infection activity for the study of HCV infection.
T5127 ABT530 1353900-92-1 98%
ABT530 (Pibrentasvir) is an HCV NS5A inhibitor with EC50s ranging from 1.4-5.0 pM against HCV replicons containing NS5A from genotypes 1-6.
T15603 ITX5061 1252679-52-9 98%
ITX5061 is a type II inhibitor of p38 MAPK and scavenger receptor B1 (SRB1) antagonist for the study of hepatitis C virus infection.
T5938 4-Phenoxybenzylamine 107622-80-0 98%
4-Phenoxybenzylamine inhibits the function of the NS3 protein by stabilizing an inactive conformation with an IC50 of about 500 μM against HCV NS3/4a .
T22489 2'-MeCCPA 205171-12-6 98%
2'-MeCCPA is a potent and highly selective A1 adenosine receptor (A1AR) agonist with a K-value of 1.8 nM for AR.2'-MeCCPA inhibits trichostatin-stimulated adenyl...
T19073 Tris(4-aminophenyl)methane 548-61-8 98%
Tris(4-aminophenyl)methane (Leucopararosaniline), a triphenylmethane dye, is a weak HCV helicase inhibitor.
T9717 Chlorcyclizine 82-93-9 98%
CHLORCYCLIZINE is a histamine H1 antagonist and a potent hepatitis C virus (HCV) entry inhibitor.
TN6508 Trachelogenin 34209-69-3 98%
Trachelogenin ((-)-Trachelogenin), an HCV entry inhibitor, has antiproliferative effects, and its mechanism is related to affecting the phosphorylation of key pr...
T16165 Myriocin 35891-70-4 98%
Myriocin (Thermozymocidin), a metabolite derived from Myriococcum albomyces, is a serine-palmitoyltransferase (SPT) inhibitor with potential antitumour, anticanc...
T7607 PSI-6130 817204-33-4 98%
PSI-6130 (R 1656) is a potent and selective HCV NS5B polymerase inhibitor. PSI-6130 inhibits HCV replication with a mean IC50 of 0.6 μM.
T25268L Coblopasvir dihydrochloride 1966138-53-3 98%
Coblopasvir dihydrochloride can be used to study chronic HCV infection and is a pan-genotypic nonstructural protein 5A (NS5A) inhibitor.
T50024 7-benzyl-5,6-dimethyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine 56344-53-7 98%
7-benzyl-5,6-dimethyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine is a inhibitor of Hepatitis C Virus(HCV).
T38237 2′-O-Methylcytidine 2140-72-9 98%
2'-O-Methylcytidine is a nucleoside derivative and an inhibitor of hepatitis C virus (HCV) non-structural protein 5B (NS5B; IC50= 3.8 μM).1It inhibits HCV replic...
TN2089 Platycodin D3 67884-03-1 98%
Platycodin D3 is a NF-κB inhibitor, it could as expectorants in diverse inflammatory pulmonary diseases, it can regulate the production and secretion of airway m...
Samatasvir
T9567
Samatasvir (ATOLIHZIXHZSBA-BTSKBWHGSA-N) is a pan-genotypic inhibitor of the HCV non-structural protein 5A.
Mericitabine
T16710
Mericitabine (R-7128) is a nucleoside HCV NS5B polymerase inhibitor. It acts as an RNA chain terminator and prevents the elongation of RNA transcripts during rep...
Merimepodib
T3444
Merimepodib (VX-497) is a novel noncompetitive inhibitor of Inosine monophosphate dehydrogenase(IMPDH).
Pseudane IX
T38375
Pseudane IX (2-nonyl-1H-quinolin-4-one) reduces infection of Huh 7.5 cells by hepatitis C virus (HCV) with an IC50 of 1.4 μg/ml.
PSI-6206
T2117
PSI-6206 (RO 2433) (RO2433) is a selective HCV RNA polymerase inhibitor.
FGI-106 tetrahydrochloride
T11281L
FGI-106 tetrahydrochloride is active against Ebola, Rift Valley and Dengue Fever viruses with EC50s of 100 nM, 800 nM and 400-900 nM, respectively. FGI-106 tetra...
Isatoribine
T24178
Isatoribine(ANA245) free base is a potent TLR7 receptor agonist with anti-hepatitis C virus infection activity for the study of HCV infection.
ABT530
T5127
ABT530 (Pibrentasvir) is an HCV NS5A inhibitor with EC50s ranging from 1.4-5.0 pM against HCV replicons containing NS5A from genotypes 1-6.
ITX5061
T15603
ITX5061 is a type II inhibitor of p38 MAPK and scavenger receptor B1 (SRB1) antagonist for the study of hepatitis C virus infection.
4-Phenoxybenzylamine
T5938
4-Phenoxybenzylamine inhibits the function of the NS3 protein by stabilizing an inactive conformation with an IC50 of about 500 μM against HCV NS3/4a .
2'-MeCCPA
T22489
2'-MeCCPA is a potent and highly selective A1 adenosine receptor (A1AR) agonist with a K-value of 1.8 nM for AR.2'-MeCCPA inhibits trichostatin-stimulated adenyl...
Tris(4-aminophenyl)methane
T19073
Tris(4-aminophenyl)methane (Leucopararosaniline), a triphenylmethane dye, is a weak HCV helicase inhibitor.
Chlorcyclizine
T9717
CHLORCYCLIZINE is a histamine H1 antagonist and a potent hepatitis C virus (HCV) entry inhibitor.
Trachelogenin
TN6508
Trachelogenin ((-)-Trachelogenin), an HCV entry inhibitor, has antiproliferative effects, and its mechanism is related to affecting the phosphorylation of key pr...
Myriocin
T16165
Myriocin (Thermozymocidin), a metabolite derived from Myriococcum albomyces, is a serine-palmitoyltransferase (SPT) inhibitor with potential antitumour, anticanc...
PSI-6130
T7607
PSI-6130 (R 1656) is a potent and selective HCV NS5B polymerase inhibitor. PSI-6130 inhibits HCV replication with a mean IC50 of 0.6 μM.
Coblopasvir dihydrochloride
T25268L
Coblopasvir dihydrochloride can be used to study chronic HCV infection and is a pan-genotypic nonstructural protein 5A (NS5A) inhibitor.
7-benzyl-5,6-dimethyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine
T50024
7-benzyl-5,6-dimethyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine is a inhibitor of Hepatitis C Virus(HCV).
2′-O-Methylcytidine
T38237
2'-O-Methylcytidine is a nucleoside derivative and an inhibitor of hepatitis C virus (HCV) non-structural protein 5B (NS5B; IC50= 3.8 μM).1It inhibits HCV replic...
Platycodin D3
TN2089
Platycodin D3 is a NF-κB inhibitor, it could as expectorants in diverse inflammatory pulmonary diseases, it can regulate the production and secretion of airway m...
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