T1819 |
Nexturastat A
|
1403783-31-2
|
98%
|
|
Nexturastat A is an effective and specific HDAC6 inhibitor (IC50: 5 nM). Its selectivity is >190-fold than other HDACs.
|
T11329 |
FT895
|
2225728-57-2
|
98%
|
|
FT895 is a selective and potent HDAC11 inhibitor with antifungal and antitumor activity that inhibits HDAC11 expression and limits EV71 replication in vitro.
|
T2294 |
BG45
|
926259-99-6
|
98%
|
|
BG45 is an HDAC I type inhibitor with IC50 of 289 nM, 2.0 μM, 2.2 μM and >20 μM for HDAC3/1/2/6 in cell-free assays, respectively.
|
T3509 |
ACY-738
|
1375465-91-0
|
98%
|
|
ACY-738 demonstrates inhibitory activity against recombinant HDAC6 (IC50: 1.7 nM), with respective average selectivity over class I HDACs being 100-fold.
|
T17028 |
Tefinostat
|
914382-60-8
|
98%
|
|
Tefinostat (CHR-2845) is a potent monocyte/macrophage-targeted histone deacetylase (HDAC) inhibitor. Tefinostat is cleaved to the active acid CHR-2847 by the int...
|
T9745 |
Elevenostat
|
1454902-97-6
|
98%
|
|
Elevenostat is an HDAC11-selective inhibitor with an IC50 value of 0.235 µM.
|
T10777 |
CG347B
|
1598426-03-9
|
98%
|
|
CG347B is a selective inhibitor of HDAC6.
|
T14305 |
Apicidin
|
183506-66-3
|
98%
|
|
Apicidin (OSI 2040) is a histone deacetylase (HDAC) inhibitor with antiparasitic activity and antiproliferative activity.Apicidin attenuates memory deficits, inh...
|
T77664 |
KH16
|
|
98%
|
|
KH16 is a potent HDAC inhibitor that specifically targets class I HDACs (HDAC1, HDAC2 and HDAC3) with IC50 values between 6 and 34 nM. KH16 is able to stimulate ...
|
T3206 |
NKL 22
|
537034-15-4
|
98%
|
|
NKL 22 (Histone Deacetylase Inhibitor IV) is an effective Histone Deacetylase Inhibitor.
|
TQ0074 |
ACY-775
|
1375466-18-4
|
98%
|
|
ACY-775 is an effective and specific inhibitor of HDAC6 (IC50: 7.5 nM).
|
T8517 |
Belinostat
|
866323-14-0
|
98%
|
|
Belinostat (PXD101) is an inhibitor of hydroxamic acid-type histone deacetylase (HDAC, IC50 of 27 nM in HeLa cell extracts),and with antineoplastic activity.
|
T4481 |
Tucidinostat
|
1616493-44-7
|
98%
|
|
Tucidinostat (Chidamide) is an effective and orally bioavailable HDAC enzymes class I (HDAC1/2/3) and class IIb (HDAC10) inhibitor, with IC50s of 95, 160, 67 and...
|
T16545 |
Pivanex
|
122110-53-6
|
98%
|
|
Pivanex (Pivalyloxymethyl butyrate) is an orally active HDAC inhibitor and an antimetastatic and antiangiogenic agent. Pivanex downregulates the Bcr-Abl protein ...
|
T26897 |
BRD2492
|
1821669-43-5
|
98%
|
|
BRD2492 is a selective and potent dual inhibitor of HDAC1 and HDAC2 with potential anticancer, antitumour and antiproliferative activities, inhibiting HDAC1/2, H...
|
T3204 |
BML-210
|
537034-17-6
|
98%
|
|
BML-210 (CAY10433) is a new-type HDAC inhibitor.
|
T5886 |
4-Phenylbutyric acid
|
1821-12-1
|
98%
|
|
4-Phenylbutyric acid (Benzenebutyric acid) is an inhibitor of HDAC,and is an antineoplastic agent.
|
T2025 |
HDAC-IN-7
|
743420-02-2
|
98%
|
|
HDAC-IN-7 (HBI-8000) (Chidamide impurity) is an impurity of Chidamide. Chidamide is a potent and orally bioavailable inhibitor of HDAC enzymes class I (HDAC1/2/3...
|
T6S0033 |
Crotonoside
|
1818-71-9
|
98%
|
|
1. Crotonoside (Isoguanosine) has much more active than adenosine in reducing the blood pressure in rabbits and cats, in decreasing the tone of isolated intestin...
|
T21551 |
2-hexyl-4-Pentynoic Acid
|
96017-59-3
|
98%
|
|
2-hexyl-4-Pentynoic Acid, a valproic acid (VPA) derivatives, is a potent and robust HDACs inhibitor with IC50 value of 13 μM.
|