T4717 |
25-Hydroxycholesterol
|
2140-46-7
|
|
|
25-Hydroxycholesterol is a steroid derivative that suppresses the cleavage of sterol regulatory element binding proteins (SREBPs). It inhibits HMG-CoA reductase ...
|
T26644 |
Apomine
|
126411-13-0
|
100%
|
|
Apomine (SR-9223i), an inhibitor of HMG-CoA-reductase, promotes apoptosis of myeloma cells in vitro and has been implicated in the regulation of myeloma in vivo....
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T14342 |
Atorvastatin lactone
|
125995-03-1
|
96.60%
|
|
Atorvastatin lactone is a prodrug form of atorvastatin. Which is an orally active 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitor.
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T0683 |
Mevastatin
|
73573-88-3
|
97.96%
|
|
Mevastatin (ML236B) is an HMG-CoA reductase inhibitor that was initially isolated from the mold Pythium ultimum. Mevastatin was the first statin to enter clinica...
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T25285 |
Dalvastatin
|
132100-55-1
|
98.08%
|
|
Dalvastatin (RG-12561) is an orally available inhibitor of HMG-CoA reductase and cholesterol-lowering synthesis.Dalvastatin competitively inhibits rat hepatic HM...
|
TN1733 |
Hesperetin 7-O-glucoside
|
31712-49-9
|
98.1%
|
|
Hesperetin 7-O-glucoside and prunin are direct precursors of naringin and neohesperidin, respectively, in C. aurantium. Hesperetin 7-O-glucoside shows inhibition...
|
T1510 |
Rosuvastatin calcium
|
147098-20-2
|
98.85%
|
|
Rosuvastatin calcium (ZD4522) , a selective and competitive inhibitor of hepatic hydroxymethyl-glutaryl coenzyme A (HMG-CoA) reductase, has antilipidemic activit...
|
T12092 |
Monacolin J
|
79952-42-4
|
98.87%
|
|
Monacolin J (Antibiotic MB 530A) is a cholesterol biosynthesis inhibitor.
|
T21405 |
Fluvastatin
|
93957-54-1
|
98.94%
|
|
Fluvastatin (XU-62320) is a potent and competitive HMG-CoA reductase inhibitor (IC50: 8 nM) that inhibits oxidative stress in vascular smooth muscle cells throug...
|
T0672 |
Pravastatin sodium
|
81131-70-6
|
99.08%
|
|
Pravastatin sodium (CS-514 (sodium)), an HMG-CoA reductase inhibitor, inhibits sterol synthesis with IC50 of 5.6 μM.
|
T1487 |
Fluvastatin sodium
|
93957-55-2
|
99.46%
|
|
Fluvastatin sodium (Fluvastatin sodium salt), a competitive inhibitor of hydroxymethylglutaryl-coenzyme A reductase (HMGCR), is a commonly used cholesterol lower...
|
T13131 |
Tert-Buthyl Pitavastatin
|
586966-54-3
|
99.57%
|
|
tert-Buthyl Pitavastatin is Pitavastatin metabolite. Pitavastatin is a potent inhibitor of HMG-CoA reductase.
|
T1207 |
Lovastatin
|
75330-75-5
|
99.59%
|
|
Lovastatin (MK-803) is an HMG-CoA Reductase Inhibitor, used for lowering cholesterol.
|
T3698 |
Alpha-Asarone
|
2883-98-9
|
99.59%
|
|
alpha-Asarone (trans-Asarone) is a psychoactive compound with antidepressant-like activity in mice.
|
T10324 |
Anhydrosimvastatin
|
210980-68-0
|
99.63%
|
|
Anhydrosimvastatin (Dehydro simvastatin) is an impurity of Simvastatin. Simvastatin is an HMG-CoA reductase inhibitor.
|
T24865 |
Tenivastatin
|
121009-77-6
|
99.68%
|
|
Tenivastatin (Simvastatin acid) is an anti-hyperlipidemic HMG-CoA reductase inhibitor that inhibits the production of reactive oxygen species (ROS) and can be us...
|
T20765 |
Atorvastatin
|
134523-00-5
|
99.69%
|
|
Atorvastatin is an orally active HMG-CoA reductase inhibitor that has the ability to effectively lower blood lipids by activating liver cytochrome p450 to accele...
|
T2534 |
Pitavastatin calcium
|
147526-32-7
|
99.71%
|
|
Pitavastatin calcium (NK-104) is a potent inhibitor of HMG-CoA reductase (Ki: 1.7 nM). It lowers both total cholesterol and low-density lipoprotein cholesterol i...
|
T1664 |
Meglutol
|
503-49-1
|
99.73%
|
|
Meglutol (3-Hydroxy-3-methylglutaric acid) is an antilipemic agent which lowers cholesterol, triglycerides, serum beta-lipoproteins and phospholipids. It acts by...
|
TN1438 |
Beta-Amyrin acetate
|
1616-93-9
|
99.74%
|
|
beta-Amyrin acetate inhibits HMG-CoA Reductase (HMGCR) and sEH activity with IC50 of 3.4 μM. beta-Amyrin acetate has anti-inflammatory, antifungal, antioxidant, ...
|