T3257 |
UNC0638
|
1255580-76-7
|
98%
|
|
UNC0638 is an inhibitor of β-protein lysine methyltransferases G9a(IC50<15 nM) and GLP(IC50=19 nM) with excellent potency and selectivity over a wide range of ep...
|
T28036 |
MI-2-2
|
1454920-20-7
|
98%
|
|
MI-2-2 is an inhibitor of bivalent protein-protein interaction between menin and MLL with an IC50 of 46 nM. MI-2-2 binds to menin with Kd of 22 nM.
|
T4393 |
MS049 2HCl (1502816-23-0(free base))
|
T4393
|
98%
|
|
MS049 is a potent and selective inhibitor of PRMT4 (IC50 = 34 nM) and PRMT6 (IC50 = 43 nM). It is less active against additional type I PRMTs (IC50s = >130, >220...
|
T5322 |
BCI-121
|
432529-82-3
|
98%
|
|
BCI-121 is a substrate-competitive SMYD3 inhibitor that inhibits the proliferation of the cancer cell.
|
T0174 |
Cyproheptadine hydrochloride sesquihydrate
|
41354-29-4
|
98%
|
|
Cyproheptadine hydrochloride sesquihydrate, an antihistamine, is an antagonist of serotonin and histamine2.
|
T3084 |
SGC707
|
1687736-54-4
|
98%
|
|
SGC707 is a potent, selective, and cell-active allosteric inhibitor of PRMT3.
|
T6803 |
Chaetocin
|
28097-03-2
|
98%
|
|
Chaetocin, a natural product from Chaetomium species, is a histone methyltransferase inhibitor with IC50 of 0.8 μM, 2.5 μM and 3 μM for dSU(VAR)3-9, mouse G9a an...
|
T16886 |
Sinefungin
|
58944-73-3
|
98%
|
|
Sinefungin is an effective inhibitor of virion mRNA(guanine-7-)-methyltransferase, mRNA(nucleoside-2'-)-methyltransferase, and viral multiplication. Sinefungin i...
|
T36798 |
SW2_110A
|
2579696-95-8
|
98%
|
|
SW2_110A is a cell-permeable, selective chromosome group 8 chromosome domain (CBX8 ChD) inhibitor with a Kd of 800 nM. In vitro, SW2_110A is 5-fold more selectiv...
|
T15194 |
EBI-2511
|
2098546-05-3
|
98%
|
|
EBI-2511 is a highly potent and orally active inhibitor of EZH2 (IC50: 6 nM in Pfeffiera cell lines).
|
T6879 |
LLY-507
|
1793053-37-8
|
98%
|
|
LLY-507 is an effective, cell-active, and specific inhibitor of protein-lysine Methyltransferase SMYD2.
|
T13954 |
UNC6852
|
2688842-08-0
|
98%
|
|
UNC6852 contains an EED ligand (IC50 = 247 nM) and a von Hippel-Lindau ligand and is a selective polycomb repressive complex 2 (PRC2) degrader based on PROTAC.
|
T2097 |
C-7280948
|
587850-67-7
|
98%
|
|
C-7280948 is a PRMT1 inhibitor.
|
T4021 |
UNC3866
|
1872382-47-2
|
98%
|
|
UNC3866 is a potent antagonist of the CBX7-H3 interaction as determined by AlphaScreen.
|
T9584 |
UNC6934
|
2561494-77-5
|
98%
|
|
UNC6934 is a chemical probe targeting the N-terminal PWWP (PWWP1) domain of NSD2.
|
T2354 |
UNC 0631
|
1320288-19-4
|
98%
|
|
UNC0631 is a effectvie histone methyltransferase G9a inhibitor (IC50=4 nM).
|
T8879 |
MR837
|
1210906-48-1
|
98%
|
|
ZINC30303842 is a NSD2-PWWP1 antagonist.
|
T4021L |
UNC3866 TFA(1872382-47-2 free base)
|
1872382-48-3
|
98%
|
|
UNC3866 TFA is a potent antagonist of the CBX7-H3 interaction as determined by AlphaScreen.
|
T1905 |
EPZ005687
|
1396772-26-1
|
98%
|
|
EPZ005687 is a potent and selective inhibitor of EZH2.
|
T2643 |
MI-3
|
1271738-59-0
|
98%
|
|
MI-3 (Menin-MLL Inhibitor) is an effective inhibitor of Menin-MLL interaction (IC50: 648 nM).
|