| T61214 |
EWP 815
|
20231-01-0
|
98%
|
|
|
EWP 815 is a disulfiram analogue that functions as a powerful inhibitor of Ins(1,4) P 2 phosphatase, Ins(1,4,5) P 3 5-phosphatase, and dopamine β-hydroxylase act...
|
| T15779 |
LP-533401 hydrochloride
|
1040526-12-2
|
98%
|
|
|
LP-533401 hydrochloride is an inhibitor of tryptophan hydroxylase 1. It is used for regulates serotonin production in the gut.
|
| T83969 |
Casein
|
9000-71-9
|
98%
|
|
|
Casein is a milk protein with multiple roles in a novel drug delivery system that affects postprandial amino acid delivery in different ways through its intragas...
|
| T10142L |
P-Ethynylphenylalanine hydrochloride
|
188640-63-3
|
|
|
|
p-Ethynylphenylalanine hydrochloride (4-Ethynyl-L-phenylalanine HCL) is a novel, potent and specific inhibitor of TPH[1]. The potential for p-Ethynylphenylalanin...
|
| T13383 |
Zamicastat
|
1080028-80-3
|
97.43%
|
|
|
Zamicastat (BIA 5-1058) is an inhibitor of dopamine β-hydroxylase (DBH), and is also a concentration-dependent dual inhibitor of P-gp and BCRP(IC50 values of 73....
|
| T15796 |
LX-1031
|
945976-76-1
|
97.97%
|
|
|
LX-1031 is an effective inhibitor of tryptophan 5-hydroxylase. LX-1031 decreases serotonin (5-HT) synthesis peripherally.
|
| T3268 |
Mildronate
|
76144-81-5
|
98%
|
|
|
Mildronate (Meldonium) is an inhibitor of biosynthesis of L-carnitine by gamma-butyrobetaine (GBB) hydroxylase and as a competitive inhibitor of renal carnitine ...
|
| T10142 |
P-Ethynylphenylalanine
|
278605-15-5
|
98.04%
|
|
|
p-Ethynylphenylalanine (4-Ethynyl-L-phenylalanine), a tryptophan hydroxylase (TPH) inhibitor, is competitive, effective, selective, and reversible, with a Ki of ...
|
| T11897 |
Telotristat ethyl
|
1033805-22-9
|
98.11%
|
|
|
Telotristat ethyl (LX1606) is a orally-delivered inhibitor of tryptophan hydroxylase that reduces serotonin production.
|
| T1447 |
Fenclonine
|
7424-00-2
|
98.81%
|
|
|
Fenclonine (CP-10188) is a selective and irreversible inhibitor of tryptophan hydroxylase, a rate-limiting enzyme in the biosynthesis of serotonin (5-HYDROXYTRYP...
|
| T1896 |
Ro 61-8048
|
199666-03-0
|
98.86%
|
|
|
Ro 61-8048 is a potent and selective inhibitor of kynurenine hydroxylase with an IC50 value of 37 nM.
|
| T15124 |
Diethyl-pythiDC
|
1821370-70-0
|
98.87%
|
|
|
Diethyl-pythiDC is an collagen prolyl 4-hydroxylase inhibitor.
|
| T41143 |
PCPA methyl ester hydrochloride
|
14173-40-1
|
99.08%
|
|
|
pCPA methyl ester hydrochloride (4-Chloro-DL-phenylalanine methyl ester hydrochloride) is an inhibitor of tryptophan hydroxylase inhibitor and 5-HT synthesis. pC...
|
| T4277 |
Osilodrostat
|
928134-65-0
|
99.10%
|
|
|
Osilodrostat (LCI699) (LCI699) is an effective inhibitor of human 11β-hydroxylase (IC50: 2.5 nM) and aldosterone synthase (IC50: 0.7 nM).
|
| T6044 |
Telotristat Etiprate
|
1137608-69-5
|
99.21%
|
|
|
Telotristat Etiprate (LX 1606 Hippurate) is an orally bioavailable, tryptophan hydroxylase (TPH) inhibitor with potential antiserotonergic activity.
|
| T14119 |
ACT-678689
|
1783256-96-1
|
99.45%
|
|
|
ACT-678689 (Compound Example 1.53.4) (Compound Example 1.53.4) is a tryptophan hydroxylase (TPH) inhibitor with an IC50 of 8 nM[1].
|
| T21506 |
Telotristat
|
1033805-28-5
|
99.49%
|
|
|
Telotristat is the active metabolite of LX1606(Telotristat etiprate), which is an orally bioavailable tryptophan hydroxylase (TPH) inhibitor and shows potential ...
|
| T41274 |
P-Fluoro-L-phenylalanine
|
1132-68-9
|
99.53%
|
|
|
p-Fluoro-L-phenylalanine is a substrate for tyrosine hydroxylase (TH) that can be used to study the regulation of that enzyme. p-Fluoro-L-phenylalanine binds to ...
|
| T0679 |
Ketoconazole
|
65277-42-1
|
99.62%
|
|
|
Ketoconazole (R-41400), a CYP3A4 inhibitor, is an imidazole anti-fungal agent.
|
| T6604 |
Nepicastat hydrochloride
|
170151-24-3
|
99.81%
|
|
|
Nepicastat hydrochloride (RS-25560-197 hydrochloride) is an effective and specific inhibitor, which is used for bovine and human dopamine-β-hydroxylase with IC50...
|
