| T76810 |
Ganitumab
|
905703-97-1
|
98%
|
Ganitumab
|
|
Ganitumab (AMG 479) is a highly potent monoclonal antibody to type 1 insulin-like growth factor receptor (IGF1R). Ganitumab is recognized to bind to IGF1R at low...
|
| T76727 |
Teprotumumab
|
1036734-93-6
|
98%
|
Teprotumumab
|
|
Teprotumumab is a human monoclonal antibody that blocks the IGF-1 receptor (IGF-1R). Teprotumumab binds to the extracellular α-subunit domain ligand of IGF-1R. T...
|
| T9980 |
AVJ16
|
|
98%
|
|
|
AVJ16 as a member of the insulin growth factor 2 mRNA-binding protein family, binds to the mRNA of certain genes to regulate protein translation.
|
| TN7108 |
Urolithin C
|
165393-06-6
|
|
|
|
Urolithin C is a gut metabolite of ellagic acid. Urolithin C induces apoptosis in PC12 cells through a mitochondria-mediated pathway.
|
| T6S1487 |
Ginsenoside Rg5
|
186763-78-0
|
|
|
|
1. Ginsenoside Rg5 could be a beneficial agent for the treatment of Alzheimer's disease. 2. Ginsenoside Rg5 suppresses LPS-induced nitric oxide (NO) production a...
|
| TP1125 |
Insulin(cattle)
|
11070-73-8
|
|
|
|
Insulin bovine (Insulin from bovine pancreas) is a biologically derived two-chain polypeptide hormone, synthesized in vivo by pancreatic β cells. It is frequentl...
|
| T9030 |
SU4984
|
186610-89-9
|
100%
|
|
|
SU4984 is a cell-permeable, ATP-competitive and reversible inhibitor of the fibroblast growth factor receptor 1 (FGFR1).
|
| T3621 |
Brigatinib
|
1197953-54-0
|
100%
|
|
|
Brigatinib (AP-26113) is a highly potent and selective ALK inhibitor.
|
| T76795 |
Xentuzumab
|
1417158-65-6
|
95.21%
|
|
|
Xentuzumab (BI836845) is a recombinant monoclonal antibody to humanised IGF ligand that inhibits IGF1 and IGF2 growth-promoting signalling and inhibits AKT activ...
|
| TP2209L |
Xenin 8 acetate
|
TP2209L
|
95.54%
|
|
|
Xenin 8 acetate is a biologically active fragment of Xenin in the neurotensin/xenopsin family. Xenin 8 acetate augments Arginine-induced insulin release (by 40%)...
|
| T11593 |
I-OMe-Tyrphostin AG 538
|
1094048-77-7
|
96.66%
|
|
|
I-OMe-Tyrphostin AG 538 is a specific IGF-1R inhibitor and ATP-competitive inhibitor of PI5P4Kα (IC50: 1 µM).I-OMe-Tyrphostin AG 538 inhibits IGF-1R-mediated sig...
|
| T13564L |
AZ7550 hydrochloride
|
2309762-40-9
|
97.07%
|
|
|
AZ7550 hydrochloride (AZ7550 hydrochloride ), an active metabolite of AZD9291, inhibits the activity of IGF1R (IC50: 1.6 μM).
|
| T13564 |
AZ7550
|
1421373-99-0
|
97.07%
|
|
|
AZ7550, an active metabolite of AZD9291, inhibits the activity of IGF1R (IC50: 1.6 μM).
|
| T4605 |
NT157
|
1384426-12-3
|
97.55%
|
|
|
NT157 is a small molecule tyrphostin targeting IRS protein and has the potential to inhibit IGF-1R and STAT3 signaling pathways in TME cancer cells and stromal c...
|
| T3059 |
ALK-IN-1
|
1197958-12-5
|
97.66%
|
|
|
ALK-IN-1 (AP26113) is a potent ALK inhibitor with IC50 of 0.62 nM in a cell-free assay, demonstrated ability overcome Crizotinib resistance mediated by a L1196M ...
|
| T1918 |
NVP-TAE 226
|
761437-28-9
|
98.07%
|
|
|
NVP-TAE 226 (TAE226) is an effective FAK inhibitor (IC50: 5.5 nM) and most effective to Pyk2(IC50: 3.5 nM); 10- to 100-fold less effective against IGF-1R, InsR, ...
|
| T2642 |
PD173074
|
219580-11-7
|
98.15%
|
|
|
PD173074 is an effective FGFR1 inhibitor (IC50: 25 nM) and also inhibits VEGFR2 (IC50: 100-200 nM) in cell-free assays. The selectivity is higher ~1000-fold for ...
|
| T37588L |
GIP (1-30) amide, porcine acetate
|
|
98.50%
|
|
|
GIP (1-30) amide, porcine acetate is an agonist of fully glucose-dependent insulinotropic polypeptide (GIP) receptor. GIP (1-30) amide, porcine acetate can weakl...
|
| T10285 |
ALK inhibitor 1
|
761436-81-1
|
98.55%
|
|
|
ALK inhibitor 1 is a selective ALK kinase inhibitor.
|
| TP2018L |
GIP (human) acetate
|
TP2018L
|
98.65%
|
|
|
GIP (human) acetate is a stimulator of glucose-dependent insulin secretion and a weak inhibitor of gastric acid secretion. GIP (human) acetate plays a vital role...
|
