T2647 |
IDO5L
|
914471-09-3
|
100%
|
|
IDO5L (INCB024360 analogue) is an effective IDO1 inhibitor(IC50=10 nM).
|
T1847 |
Necrostatin-1
|
4311-88-0
|
100%
|
|
Necrostatin-1 (Nec-1) is a necrotic apoptosis inhibitor and RIP1 inhibitor with specificity. Necrostatin-1 inhibits TNF-α-induced necrotic apoptosis. Necrostatin...
|
T3S1967 |
(S)-Indoximod
|
21339-55-9
|
95.39%
|
|
(S)-Indoximod (L-Abrine) exhibits inhibition of rabbit small intestine indoleamine 2, 3-dioxygenase, competitive inhibition of IDO, reduction of Foxp3 protein ex...
|
T11901 |
IDO1-IN-5
|
2166616-75-5
|
96.7%
|
|
IDO1-IN-5 is a selective, potent and brain penetrated inhibitor of IDO1 activity, binds to apo-IDO1 lacking heme rather than mature heme-bound IDO1.
|
T4S0051 |
Coptisine sulfate
|
1198398-71-8
|
98%
|
|
1. Coptisine sulfate has growth inhibitory activity against human cancer cell line in the NCI's anticancer drug screening program.
|
T7181 |
IDO-IN-1
|
914638-30-5
|
98%
|
|
IDO-IN-1 is a potent indoleamine 2,3-dioxygenase (IDO) inhibitor( IC50 values of 59 and 12 nM for human IDO enzymatic activity and HeLa cell assays, respectively...
|
T3548 |
Epacadostat
|
1204669-58-8
|
98.08%
|
|
Epacadostat (INCB 024360) is an oral-available inhibitor of indoleamine 2, 3-dioxygenase (IDO1), increasing the proliferation and activation of various immune ce...
|
T9164 |
BMS-986242
|
1923844-48-7
|
98.25%
|
|
BMS-986242 is an orally active, potent and selective inhibitor of indoleamine-2,3-dioxygenase 1 (IDO1), and it can be used for the research of cancer.
|
T5S0056 |
Coptisine chloride
|
6020-18-4
|
98.85%
|
|
1. Coptisine chloride (NSC-119754) can be absorbed across intestinal epithelial cells, and completely absorbed compounds.
|
T39476 |
NLG802
|
2071683-99-1
|
99.08%
|
|
NLG802 is a prodrug of indoximod, an orally active indoleamine 2,3-dioxygenase (IDO) inhibitor.
|
T7660 |
IDO inhibitor 1
|
1204669-37-3
|
99.16%
|
|
IDO inhibitor 1 is an potent inhibitor of indoleamine-2,3 dioxygenase (IDO) ( IC50 <100 nM).with potential immunomodulating and antineoplastic activities.
|
T10199 |
GNF-PF-3777
|
77603-42-0
|
99.47%
|
|
GNF-PF-3777 (8-Nitrotryptanthrin) (8-Nitrotryptanthrin) is a potent inhibitor of human indoleamine 2,3-dioxygenase 2 (hIDO2; Ki: 0.97 μM).
|
T5S0802 |
Palmatine
|
3486-67-7
|
99.49%
|
|
1. Palmatine (Burasaine) is an inhibitor of dopamine generation. 2. Palmatine could potentially be developed for the treatment of flavivirus infections. 3. Palma...
|
T6543 |
Indoximod
|
110117-83-4
|
99.5%
|
|
Indoximod (Indoximod (NLG-8189)) is a methylated tryptophan with immune checkpoint inhibitory activity. Indoximod inhibits the enzyme indoleamine 2, 3-dioxygenas...
|
T11616 |
IDO-IN-13
|
2291164-02-6
|
99.57%
|
|
IDO-IN-13 (GS-4361) is a potent indoleamine 2,3-dioxygenase 1 (IDO1) inhibitor (EC50: 17 nM).
|
T11615 |
IDO-IN-12
|
1888341-29-4
|
99.61%
|
|
IDO-IN-12 is an inhibitor of indoleamine 2,3-dioxygenase (IDO).
|
T2718 |
Palmatine chloride
|
10605-02-4
|
99.64%
|
|
Palmatine chloride an isoquinoline alkaloid, is an important medicinal herbal extract with diverse pharmacological and biological properties.
|
TQ0071 |
Navoximod
|
1402837-78-8
|
99.81%
|
|
Navoximod (GDC-0919) (NLG- 919, GDC-0919) is a potent indoleamine-(2,3)-dioxygenase (IDO) pathway inhibitor (Ki/EC50: 7 nM/75 nM).
|
T4532 |
Linrodostat
|
1923833-60-6
|
99.84%
|
|
Linrodostat (BMS-986205) is a selective indoleamine 2, 3-dioxygenase 1 (IDO1) inhibitor.
|
T1806 |
IDO-IN-7
|
1402836-58-1
|
99.87%
|
|
IDO-IN-7 (NLG-919 analogue) is a potent IDO (indoleamine-(2, 3)-dioxygenase) pathway inhibitor.
|