Cat. No. | 製品名 | CAS No. | Purity | Chemical Structure |
---|---|---|---|---|
T5310 | TR-14035 | 232271-19-1 | 98% |
|
TR-14035 (MDK-1191) is a dual antagonist of α4β7/α4β1 integrins (IC50s: 7/87nM). | ||||
T21868 | BIO-1211 | 187735-94-0 | 98% |
|
BIO-1211 is a more potent inhibitor of α4β1 (VLA-4, IC50 = 4 nM) over α4β7(IC50 = 2 μM). | ||||
T4435 | E7820 | 289483-69-8 | 98% |
|
E7820 (ER68203-00) is an angiogenesis inhibitor by suppressing integrin a2 (a cell adhesion molecule expressed on endothelial cells). | ||||
T39933 | Bexotegrast | 2376257-44-0 | 98% |
|
Bexotegrast (PLN-74809) is an orally active and potent inhibitor of αvβ6 and αvβ1 integrins with antifibrotic effects, inhibits αvβ6 and αvβ1-induced activation ... | ||||
T14676 | BMS-688521 | 893397-44-9 | 98% |
|
BMS-688521 BMS-688521 is an orally active and potent inhibitor of LFA-1/ICAM interaction, a small molecule antagonist of leukocyte function-associated antigen-1 ... | ||||
T13147 | ICAM-1-IN-1 | 251994-14-6 | 98% |
|
ICAM-1-IN-1 is a potent and selective E-selectin(IC50 = 7 nM) and ICAM-1(IC50 = 5 nM) inhibitor. | ||||
T27250 | Elarofiban | 198958-88-2 | 98% |
|
Elarofiban(RWJ-53308) is a novel and orally active GPIIb/IIIa antagonist. | ||||
TP1879L1 | P11 acetate | TP1879L1 | 98% |
|
P11 acetate is an integrin αvβ3-vitronectin interaction antagonist(IC50 = 2.74 nM). | ||||
TP1459L | Gly-Arg-Gly-Asp-Ser acetate(96426-21-0 free base) | TP1459L | 98% |
|
Gly-Arg-Gly-Asp-Ser (GRGDS) acetate is a cell binding protein domain derived from the cell-binding region of fibronectin. | ||||
T76927 | Bersanlimab | 1987854-08-9 | 98% |
|
Bersanlimab (BI-505) is a fully human monoclonal antibody targeting Intercellular Adhesion Molecule-1 (ICAM-1).Bersanlimab has anticancer properties and can be u... | ||||
T76924 | Efalizumab | 214745-43-4 | 98% |
Efalizumab
|
Efalizumab, a novel potent regulator of T cells, is a humanized LFA-1 α subunit (CD11a) monoclonal antibody. Efalizumab has inhibitory effects on T cell activati... | ||||
T76844 | Abciximab | 143653-53-6 | 98% |
Abciximab
|
Abciximab (C7E3) is a mouse/human chimeric monoclonal antibody that is a potent glycoprotein IIb/IIIa inhibitor. Abciximab has anti-platelet aggregation and leuk... | ||||
T9914 | Vedolizumab | 943609-66-3 | 98% |
|
Vedolizumab is a humanized monoclonal antibody that targets the α4β7 integrin for the treatment of Crohn's disease and ulcerative colitis. | ||||
TQ0250 | CWHM-12 | 1564286-55-0 |
|
|
CWHM-12 is a potent inhibitor of αV integrins (IC50s of 0.2/0.8/1.5/1.8 nM for αvβ8/αvβ3/αvβ6/αvβ1). | ||||
T6812L | Cyclo(-RGDfK) TFA | 500577-51-5 |
|
|
Cyclo(-RGDfK) is a selective αvβ3 integrin inhibitor(IC50 : 0.94 nM). | ||||
T7570 | RGD peptide (GRGDNP) | 114681-65-1 |
|
|
RGD peptide (GRGDNP) (RGD peptide GRGDNP(2TFA)) is a integrin-ligand interactions inhibitor. | ||||
T4613 | Arg-Gly-Asp TFA (99896-85-2(free base)) | T4613 |
|
|
Arg-Gly-Asp TFA (99896-85-2(free base)) (RGD Trifluoroacetate) is a tripeptide that effectively triggers cell adhesion, addresses certain cell lines and elicits ... | ||||
T0342 | Carvedilol phosphate hemihydrate | 610309-89-2 | 100% |
|
Carvedilol phosphate hemihydrate (BM 14190 phosphate hemihydrate) is the phosphate salt form of carvedilol, a racemic mixture and adrenergic blocking agent with ... | ||||
T4259 | GLPG0187 | 1320346-97-1 | 100% |
|
GLPG0187, a broad spectrum integrin receptor antagonist, inhibits αvβ1-integrin (IC50: 1.3 nM). | ||||
TP1474 | LXW7 | 1313004-77-1 | 100% |
|
LXW7 is an octamer disulfide cyclic peptide and αvβ3 integrin ligand, acts as a potent and specific endothelial progenitor cells (EPCs) and endothelial cells (EC... |