| T5310 |
TR-14035
|
232271-19-1
|
98%
|
|
|
TR-14035 (MDK-1191) is a dual antagonist of α4β7/α4β1 integrins (IC50s: 7/87nM).
|
| T21868 |
BIO-1211
|
187735-94-0
|
98%
|
|
|
BIO-1211 is a more potent inhibitor of α4β1 (VLA-4, IC50 = 4 nM) over α4β7(IC50 = 2 μM).
|
| T4435 |
E7820
|
289483-69-8
|
98%
|
|
|
E7820 (ER68203-00) is an angiogenesis inhibitor by suppressing integrin a2 (a cell adhesion molecule expressed on endothelial cells).
|
| T39933 |
Bexotegrast
|
2376257-44-0
|
98%
|
|
|
Bexotegrast (PLN-74809) is an orally active and potent inhibitor of αvβ6 and αvβ1 integrins with antifibrotic effects, inhibits αvβ6 and αvβ1-induced activation ...
|
| T14676 |
BMS-688521
|
893397-44-9
|
98%
|
|
|
BMS-688521 BMS-688521 is an orally active and potent inhibitor of LFA-1/ICAM interaction, a small molecule antagonist of leukocyte function-associated antigen-1 ...
|
| T13147 |
ICAM-1-IN-1
|
251994-14-6
|
98%
|
|
|
ICAM-1-IN-1 is a potent and selective E-selectin(IC50 = 7 nM) and ICAM-1(IC50 = 5 nM) inhibitor.
|
| T27250 |
Elarofiban
|
198958-88-2
|
98%
|
|
|
Elarofiban(RWJ-53308) is a novel and orally active GPIIb/IIIa antagonist.
|
| TP1879L1 |
P11 acetate
|
TP1879L1
|
98%
|
|
|
P11 acetate is an integrin αvβ3-vitronectin interaction antagonist(IC50 = 2.74 nM).
|
| TP1459L |
Gly-Arg-Gly-Asp-Ser acetate(96426-21-0 free base)
|
TP1459L
|
98%
|
|
|
Gly-Arg-Gly-Asp-Ser (GRGDS) acetate is a cell binding protein domain derived from the cell-binding region of fibronectin.
|
| T76927 |
Bersanlimab
|
1987854-08-9
|
98%
|
|
|
Bersanlimab (BI-505) is a fully human monoclonal antibody targeting Intercellular Adhesion Molecule-1 (ICAM-1).Bersanlimab has anticancer properties and can be u...
|
| T76924 |
Efalizumab
|
214745-43-4
|
98%
|
Efalizumab
|
|
Efalizumab, a novel potent regulator of T cells, is a humanized LFA-1 α subunit (CD11a) monoclonal antibody. Efalizumab has inhibitory effects on T cell activati...
|
| T76844 |
Abciximab
|
143653-53-6
|
98%
|
Abciximab
|
|
Abciximab (C7E3) is a mouse/human chimeric monoclonal antibody that is a potent glycoprotein IIb/IIIa inhibitor. Abciximab has anti-platelet aggregation and leuk...
|
| T9914 |
Vedolizumab
|
943609-66-3
|
98%
|
|
|
Vedolizumab is a humanized monoclonal antibody that targets the α4β7 integrin for the treatment of Crohn's disease and ulcerative colitis.
|
| TQ0250 |
CWHM-12
|
1564286-55-0
|
|
|
|
CWHM-12 is a potent inhibitor of αV integrins (IC50s of 0.2/0.8/1.5/1.8 nM for αvβ8/αvβ3/αvβ6/αvβ1).
|
| T6812L |
Cyclo(-RGDfK) TFA
|
500577-51-5
|
|
|
|
Cyclo(-RGDfK) is a selective αvβ3 integrin inhibitor(IC50 : 0.94 nM).
|
| T7570 |
RGD peptide (GRGDNP)
|
114681-65-1
|
|
|
|
RGD peptide (GRGDNP) (RGD peptide GRGDNP(2TFA)) is a integrin-ligand interactions inhibitor.
|
| T4613 |
Arg-Gly-Asp TFA (99896-85-2(free base))
|
T4613
|
|
|
|
Arg-Gly-Asp TFA (99896-85-2(free base)) (RGD Trifluoroacetate) is a tripeptide that effectively triggers cell adhesion, addresses certain cell lines and elicits ...
|
| T0342 |
Carvedilol phosphate hemihydrate
|
610309-89-2
|
100%
|
|
|
Carvedilol phosphate hemihydrate (BM 14190 phosphate hemihydrate) is the phosphate salt form of carvedilol, a racemic mixture and adrenergic blocking agent with ...
|
| T4259 |
GLPG0187
|
1320346-97-1
|
100%
|
|
|
GLPG0187, a broad spectrum integrin receptor antagonist, inhibits αvβ1-integrin (IC50: 1.3 nM).
|
| TP1474 |
LXW7
|
1313004-77-1
|
100%
|
|
|
LXW7 is an octamer disulfide cyclic peptide and αvβ3 integrin ligand, acts as a potent and specific endothelial progenitor cells (EPCs) and endothelial cells (EC...
|
