| T8487 |
Empesertib
|
1443763-60-7
|
98%
|
|
|
Empesertib (BAY 1161909) is an orally bioavailable and selective inhibitor Mps1(IC50 < 1 nM), with potential antineoplastic activity.
|
| T22289 |
CFI-402257
|
1610759-22-2
|
96.66%
|
|
|
CFI-402257 is a selective inhibitor of Mps1/TTK kinase (Mps1 Ki = 0.09 nM; EC50 = 6.5 nM)and can be used in studies about hepatocellular carcinoma diseases.
|
| T36816 |
S-trityl-L-Cysteine
|
2799-07-7
|
97.02%
|
|
|
S-trityl-L-Cysteine is a non-natural amino acid and an inhibitor of Eg5, also known as KSP and Kif11, a mitotic kinesin necessary for mitotic spindle formation. ...
|
| T8342 |
BRD9876
|
32703-82-5
|
97.22%
|
|
|
BRD9876 is a selective inhibitor of MM1S growth.
|
| T11155 |
Eg5 Inhibitor V, trans-24
|
869304-55-2
|
97.45%
|
|
|
Eg5 Inhibitor V, trans-24 is a specific and potent Eg5 inhibitor that can be used in cancer research with an IC50 value of 0.65 uM.
|
| T2255 |
SB-743921 hydrochloride
|
940929-33-9
|
98%
|
|
|
SB-743921 hydrochloride (SB743921 HCl) is an effective inhibitor of kinesin spindle protein, KSP, (Ki =0.1 nM).
|
| T2689 |
AZ3146
|
1124329-14-1
|
98.03%
|
|
|
AZ3146 is a selective Mps1 inhibitor with IC50 of ~35 nM.
|
| T3118 |
Dimethylenastron
|
863774-58-7
|
98.07%
|
|
|
Dimethylenastron, an Eg5 inhibitor, arrests cells with monopolar spindles to which all chromosomes attach in a syntelic manner.
|
| T1839 |
Mps1-IN-2
|
1228817-38-6
|
98.07%
|
|
|
Mps1-IN-2 is a potent, selective and ATP-competitive dual Mps1/Plk1 inhibitor.
|
| T77586 |
Eg5-IN-1
|
|
98.21%
|
|
|
Eg5-IN-1 is a potent inhibitor of the kinesin family of motor proteins (Eg5) with an IC50 value of 1.97 µM for Eg5.Eg5-IN-1 can be used in cancer research.
|
| T6393 |
ARQ 621
|
1095253-39-6
|
98.38%
|
|
|
ARQ 621 is an allosteric, and selective Eg5 mitotic motor protein inhibitor. Phase 1.
|
| T12237 |
NMS-P715
|
1202055-32-0
|
98.41%
|
|
|
NMS-P715 is a selective and ATP-competitive MPS1 inhibitor(IC50 of 182 nM).
|
| T6209 |
CW-069
|
1594094-64-0
|
98.57%
|
|
|
CW-069 (IC50=75 μM）, an allosteric selective inhibitor of microtubule motor protein HSET, exhibits remarkable specificity over KSP.
|
| T4048 |
Monastrol
|
329689-23-8
|
98.744%
|
|
|
Monastrol ((±)-Monastrol) is a potent and cell-permeable inhibitor of the mitotic kinesin Eg5.
|
| T2313 |
MPI-0479605
|
1246529-32-7
|
99.23%
|
|
|
MPI-0479605 is an ATP competitive and selective inhibitor.
|
| T3120 |
K858 (Racemic)
|
72926-24-0
|
99.5%
|
|
|
K858 Racemic (K858) is a selective mitotic kinesin Eg5 inhibitor which acts in an ATP-noncompetitive manner.
|
| T3434 |
BAY1217389
|
1554458-53-5
|
99.54%
|
|
|
BAY 1217389 is an effective and selective inhibitor of the monopolar spindle 1 (MPS1) kinase (IC50<10 nM).
|
| T2103 |
Ispinesib
|
336113-53-2
|
99.57%
|
|
|
Ispinesib (SB-715992), a selective, effectvie and reversible inhibitor of kinesin spindle protein (KSP), is derived from quinazolinone, with antineoplastic prope...
|
| T12359 |
Paprotrain
|
57046-73-8
|
99.69%
|
|
|
Paprotrain ((alphaZ)-alpha-(3-Pyridinylmethylene)-1H-indole-3-acetonitrile) inhibits the ATPase activity of MKLP-2 with an IC50 of 1.35 μM and a Ki of 3.36 μM.
|
| T2039 |
GSK-923295
|
1088965-37-0
|
99.71%
|
|
|
GSK923295 is a selective allosteric inhibitor of CENP-E kinesin motor ATPase(Ki=3.2 nM).
|
