| T2000 |
AM095
|
1345614-59-6
|
98%
|
|
|
AM095 is a potent LPA1 receptor antagonist with IC50 values of 0.98 and 0.73 μM for recombinant human or mouse LPA1 respectively.
|
| T15785 |
LPA1 receptor antagonist 1
|
1396006-71-5
|
98%
|
|
|
LPA1 receptor antagonist 1(LPA1 R antagonist 1) is a selective and potent lysophosphatidic acid (LPA1) receptor antagonist (IC50 : 25 nM) for the study of idiopa...
|
| T9699 |
TAK-615
|
1664335-55-0
|
98%
|
|
|
TAK-615 is commonly used to study pulmonary fibrosis and is a negative allosteric modulator of LPA1 receptors.
|
| T7393 |
ONO-7300243
|
638132-34-0
|
|
|
|
ONO-7300243 is an antagonist of lysophosphatidic acid receptor 1 (LPA1; IC50 : 0.16 µM).
|
| T22835 |
H2L5186303
|
139262-76-3
|
97.23%
|
|
|
H2L5186303 is an LPA2 antagonist and can be used in studies about asthma treatment.
|
| T22070 |
DBIBB
|
1569309-92-7
|
97.26%
|
|
|
DBIBB is a non-lipid agonist of specific lysophosphatidic acid (LPA2) type 2 G-protein-coupled receptor. It is a potentially active molecule for the treatment of...
|
| T6347 |
Ki16198
|
355025-13-7
|
97.6%
|
|
|
Ki16198 is the methyl ester of Ki16425, which is a LPA antagonist and inhibits LPA1- and LPA3-induced inositol phosphate production with Ki of 0.34 μM and 0.93 μ...
|
| T15796 |
LX-1031
|
945976-76-1
|
97.97%
|
|
|
LX-1031 is an effective inhibitor of tryptophan 5-hydroxylase. LX-1031 decreases serotonin (5-HT) synthesis peripherally.
|
| T7689 |
Tetradecyl Phosphonate
|
4671-75-4
|
98%
|
|
|
Tetradecyl phosphonate is a pan-antagonist of lysophosphatidic acid 1 (LPA1), LPA2, and LPA3 receptors.
|
| T22812 |
GRI977143
|
325850-81-5
|
98.07%
|
|
|
GRI977143 is a selective and non-lipid agonist of LPA2 (EC50 = 3.3 μM). GRI977143 inhibits the activation of caspases 3, 7, 8, and 9 and and reduces DNA fragment...
|
| T6108 |
Ki16425
|
355025-24-0
|
98.54%
|
|
|
Ki16425 (Debio 0719) is a competitive, potent and reversible antagonist to LPA1, LPA2 and LPA3 with Ki of 0.34 μM, 6.5 μM and 0.93 μM, respectively.
|
| T4016 |
BMS-986020
|
1257213-50-5
|
98.61%
|
|
|
BMS-986020 (AM152) is a selective antagonist of LPA1.
|
| T12684 |
Radioprotectin-1
|
1622006-09-0
|
98.75%
|
|
|
Radioprotectin-1 is a selective agonist of LPA2 with EC50 of 25 nM for murine LPA2 GPCR and exerts radioprotective and radiomitigative action.
|
| T23438 |
TC LPA5 4
|
1393814-38-4
|
99.05%
|
|
|
TC LPA5 4 is a LPA5 receptor antagonist.
|
| T21654 |
1-Oleoyl lysophosphatidic acid sodium
|
325465-93-8
|
99.24%
|
|
|
1-Oleoyl lysophosphatidic acid sodium (1-Oleoyl lysophosphatidic acid sodium salt) salt is an Endogenous agonist of LPA1 and LPA2
|
| T22834 |
H2L 5765834
|
420841-84-5
|
99.47%
|
|
|
H2L 5765834 is a lysophosphatidic acid receptors antagonist
|
| T4278 |
AM966
|
1228690-19-4
|
99.49%
|
|
|
AM966, a excellent affinity, specific, oral LPA1(IC50=17 nM) antagonist, suppresses LPA-stimulated intracellular calcium release.
|
| T4521 |
Edg-2 receptor inhibitor 1
|
1195941-38-8
|
99.69%
|
|
|
Edg-2 receptor inhibitor 1 (SAR-100842) is an Edg-2 receptor inhibitor extracted (IC50: <0.1 μM).
|
| T39647 |
BMS-986278
|
2170126-74-4
|
99.86%
|
|
|
BMS-986278 is an orally active and potent hemophosphatidic acid receptor 1 (LPA1) antagonist with Kb values of 6.9 nM and 4.0 nM for human and mouse LPA1, respec...
|
| T10293 |
AM095 free acid
|
1228690-36-5
|
99.9%
|
|
|
AM095 (free acid) is a potent LPA1 receptor antagonist (IC50s: 0.98 and 0.73 μM for recombinant human or mouse LPA1).
|
