| T6893 |
MK-886
|
118414-82-7
|
98%
|
|
|
MK-886 (L 663536) is an inhibitor of leukotriene biosynthesis, inhibiting 5-lipoxygenase-activating protein (FLAP). It is also a moderately potent PPARα antagoni...
|
| T6736 |
Zafirlukast
|
107753-78-6
|
98%
|
|
|
Zafirlukast (ICI 204219) is an orally available leukotriene receptor antagonist which is widely used for the prophylaxis and chronic treatment of asthma.
|
| T16280 |
Nedocromil
|
69049-73-6
|
98%
|
|
|
Nedocromil (FPL 59002) inhibits the action or formation of multiple mediators. Which including histamine, leukotriene C4 (LTC4), and prostaglandin D2 (PGD2).
|
| T1677 |
Montelukast
|
158966-92-8
|
100%
|
|
|
Montelukast (Singular) is an orally available leukotriene receptor antagonist which is widely used for the prophylaxis and chronic treatment of asthma and has be...
|
| T16395 |
ONO4057
|
134578-96-4
|
100%
|
|
|
ONO4057 is a potent and orally active Leukotriene B4 receptor antagonist with an IC50 value of 0.7±0.3 μM. Immunosuppressive effect of ONO4057 on rat allografts....
|
| T15647 |
Tipelukast
|
125961-82-2
|
100%
|
|
|
Tipelukast (KCA 757) is a novel orally available leukotriene receptor antagonist with anti-inflammatory activity that reduces fibrosis and down-regulates TIMP-1,...
|
| T16739 |
RG-12525
|
120128-20-3
|
96.77%
|
|
|
RG-12525（NID 525） is an orally available, selective and competitive leukotriene D (LTD) antagonist that inhibits LTC4, LTD4 and LTE4-induced contraction of guine...
|
| T5714 |
5-O-Demethylnobiletin
|
2174-59-6
|
98%
|
|
|
5-O-Demethylnobiletin (5-DEMETHYLNOBILETIN) is a natual product, has anti-inflammatory activity, it may act through a direct inhibition of 5-LOX, without affecti...
|
| T26524 |
ABT-080
|
189498-57-5
|
98.15%
|
|
|
ABT-080 (VML 530), a leukotriene synthesis inhibitor, is used potentially for treatment of asthma.
|
| T14387 |
AZD9898
|
2042347-69-1
|
98.27%
|
|
|
AZD9898 is an inhibitor of leukotriene-C4 synthetase with an IC50 of 0.28 nM. AZD9898 can be used in studies about asthma. AZD9898 mitigates the GABA binding and...
|
| T23390 |
SR 2640 hydrochloride
|
146662-42-2
|
98.36%
|
|
|
SR 2640 hydrochloride is a competitive antagonist of leukotriene D4 and E4 and can be used in studies about leukotrienes in human asthma.
|
| T3148 |
MK-571 sodium
|
115103-85-0
|
98.69%
|
|
|
MK-571 sodium (L-660711 sodium salt) is a selective, orally active antagonist of the CysLT1 receptor. MK-571 sodium is a multidrug resistance protein-2 (ABCC2, M...
|
| T30828 |
CGP 35949
|
111130-13-3
|
98.89%
|
|
|
CGP 35949 is an LTD4 antagonist with phospholipase inhibitory activity.
|
| T22358 |
Etalocib
|
161172-51-6
|
98.92%
|
|
|
Etalocib (LY293111) is a novel diaryl ether carboxylic acid derivative, is a selective and potent inhibitor of the lipoxygenase pathway either via antagonism of ...
|
| T26519 |
Ablukast
|
96566-25-5
|
99.18%
|
|
|
Ablukast (Ro 23-3544) is a leuktriene receptor antagonist. Ablukast acts as an anti-asthmatic.
|
| T24327 |
L 674573
|
127481-29-2
|
99.22%
|
|
|
L 674573 is an inhibitor of leukotriene biosynthesis.
|
| T12771 |
RS-601
|
207987-59-5
|
99.31%
|
|
|
RS-601 is a potent dual leukotriene D4/thromboxane A2 inhibitor that inhibits antigen-induced airway hyperresponsiveness (AHR) and shows asthmatic effects in a g...
|
| T1677L |
Montelukast sodium
|
151767-02-1
|
99.35%
|
|
|
Montelukast sodium (MK0476) is an orally available leukotriene receptor antagonist which is widely used for the prophylaxis and chronic treatment of asthma and h...
|
| T22946 |
LY255283
|
117690-79-6
|
99.45%
|
|
|
LY255283 is a specific antagonit of leukotriene B4 (LTB4) receptor. It inhibits the production of LTB(4) in human peripheral blood polymorphonuclear leukocytes (...
|
| T27979 |
Masilukast
|
136564-68-6
|
99.53%
|
|
|
Masilukast(MCC-847) is an oral leukotriene D4 (LTD4) receptor antagonist for the study of diseases associated with inflammation.
|
