| TN1308 |
6-Hydroxyflavanone
|
4250-77-5
|
98%
|
|
|
6-Hydroxyflavanone, extracted from the leaves of Acorus calamus, exhibits anti-inflammatory and anti-neuropathic pain activity by targeting cyclooxygenase-2 (COX...
|
| T39986 |
LOX-IN-3 dihydrochloride
|
2409964-23-2
|
98%
|
|
|
LOX-IN-3 dihydrochloride is an inhibitor of lysyl oxidase (LOX). LOX-IN-3 dihydrochloride inhibited bovine LOX (IC50<10 μM) and human LOXL2 (IC50<1 μM)activities...
|
| T3399 |
Psoralidin
|
18642-23-4
|
|
|
|
Psoralidin inhibits Akt phosphorylation and phosphatidylinositol 3-kinase activation and transcriptionally. Psoralidin possesses anticancer and chemopreventive p...
|
| TQ0180 |
Chebulagic acid
|
23094-71-5
|
|
|
|
Chebulagic acid, isolated from the Terminalia chebula Retz, is a COX-LOX dual inhibitor.
|
| TN2330 |
Phenethyl ferulate
|
71835-85-3
|
|
|
|
Phenethyl ferulate (Caffeic Acid 3-Methyl Phenethyl Ester) has chemopreventive properties against chemically induced colon carcinogenesis. It enhances apoptosis ...
|
| T6576 |
Malotilate
|
59937-28-9
|
|
|
|
Malotilate (Kantec) is a medicine used for the therapy of liver cirrhosis.
|
| T1677 |
Montelukast
|
158966-92-8
|
100%
|
|
|
Montelukast (Singular) is an orally available leukotriene receptor antagonist which is widely used for the prophylaxis and chronic treatment of asthma and has be...
|
| T70188 |
ER-34122
|
179325-62-3
|
100%
|
|
|
ER-34122, a novel orally available dual 5-lipoxygenase/cyclooxygenase inhibitor, exhibits potent anti-inflammatory activity in an arachidonic acid-induced ear in...
|
| T67908 |
ThioLox
|
1202193-89-2
|
100%
|
|
|
ThioLox is a competitive 15-lipoxygenase-1 (15-LOX-1) inhibitor with IC50 value of 12 μM. ThioLox shows anti-inflammatory and neuroprotective properties. It has ...
|
| T34624 |
Setileuton
|
910656-27-8
|
100%
|
|
|
Setileuton (MK0633) is a specific 5-LOX inhibitor and can be used in research on asthma and atherosclerosis.
|
| T68173 |
ZD-2138
|
140841-32-3
|
100%
|
|
|
ZD-2138 is a potent and selective specific inhibitor of 5-lipoxygenase (5-LOX) that inhibits allergen-induced pulmonary bronchoconstriction and reduces neurally-...
|
| T3090 |
Abietic Acid
|
514-10-3
|
92.6%
|
|
|
Abietic Acid (Sylvic acid) is the primary component of resin acid isolated from rosin.
|
| T8260 |
4',5-Dihydroxyflavone
|
6665-67-4
|
95.38%
|
|
|
4',5-Dihydroxyflavone is a soybean LOX-1(Ki: 102.6 μM) and yeast α-Glucosidase inhibitor (IC50: 66 μM).
|
| T22054 |
BW 755C
|
66000-40-6
|
96.52%
|
|
|
BW 755C is a dual inhibitor of 5-lipoxygenase (5-LO) and cyclooxygenase (COX) pathways.
|
| T1296 |
4-Aminosalicylic acid
|
65-49-6
|
97.07%
|
|
|
4-Aminosalicylic acid (para-aminosalicylic acid) is an analog of para-aminobenzoic acid (PABA) with antitubercular activity.
|
| T6485 |
Embelin
|
550-24-3
|
97.07%
|
|
|
Embelin (Embelic acid), isolated from the Japanese Ardisia herb, is an inhibitor of the X-linked inhibitor of apoptosis (IC50: 4.1 uM).
|
| T37974 |
(S)-Coriolic acid
|
29623-28-7
|
97.11%
|
|
|
(S)-Coriolic acid (13(S)-HODE) is an important intracellular signaling agent, generated by the reaction of linoleic acid with plant and mammalian lipoxygenases, ...
|
| T21838 |
1-Naphthyl 3,5-dinitrobenzoate
|
93261-39-3
|
97.42%
|
|
|
1-Naphthyl 3,5-dinitrobenzoate (JMC-4) is an inhibitor of 5-LOX can be used in studies about inflammatory therapy.
|
| T77288 |
KKII5
|
6381-55-1
|
97.44%
|
|
|
KKII5 is a potent inhibitor of the lipoxygenase LOX-1 with an IC50 of 19 μM.KKII5 inhibits lipid peroxidation and enhances the ability of the active centers of s...
|
| T61211 |
5-LOX-IN-1
|
55040-82-9
|
97.45%
|
|
|
5-LOX-IN-1 is a 5-Lipoxygenase (5-LOX) inhibitor (IC50: 2.3 μM).5-LOX-IN-1 can be used for cancer research.
|
