| T73582 |
EB1
|
42951-68-8
|
98%
|
|
|
EB1 is a potent and selective MNK kinase inhibitor with inhibitory effects on MNK1 and MNK2 with IC50 values of 0.69 μM and 9.4 μM, respectively.EB1 inhibits the...
|
| T60681 |
DS12881479
|
2373065-59-7
|
100%
|
|
|
DS12881479 can be used in cancer research which is a potent and selective inhibitor of Mnk1(IC 50 =21 nM) [1].
|
| T13564 |
AZ7550
|
1421373-99-0
|
97.07%
|
|
|
AZ7550, an active metabolite of AZD9291, inhibits the activity of IGF1R (IC50: 1.6 μM).
|
| T15250 |
ETC-206
|
1464151-33-4
|
98.11%
|
|
|
ETC-206 is a selective inhibitor of MNK1 and MNK2 (IC50s: 64 nM and 86 nM).
|
| T38960 |
QL-X-138
|
1469988-63-3
|
98.41%
|
|
|
QL-X-138 is a potent and selective BTK and MNK dual kinase inhibitor that binds covalently to BTK and non-covalently to MNK.The IC 50 s of QL-X-138 against BTK, ...
|
| T38960L |
QL-X-138 HCl
|
|
98.89%
|
|
|
QL-X-138 HCl is a novel selective and highly potent BTK/MNK dual-kinase inhibitor with anticancer activity that binds covalently to BTK and noncovalently to MNK....
|
| T12058 |
MK2-IN-3 hydrate
|
1186648-22-5
|
99.14%
|
|
|
MK2-IN-3 hydrate (MK-2 Inhibitor III) is an orally active, selective, and ATP-competitive inhibitor of MAPKAP-K2 (MK-2) (IC50 of 0.85 nM)
|
| T3468 |
Tomivosertib
|
1849590-01-7
|
99.67%
|
|
|
Tomivosertib (eFT508) is a potent, highly selective MNK1 and MNK2 inhibitor with IC50 value of 1-2 nM.
|
| T4424 |
SLV-2436
|
2095704-43-9
|
99.85%
|
|
|
SLV-2436 (SEL201-88) is a novel effective and ATP-competitive inhibitor of MNK1 and MNK2 (IC50: 10.8/5.4 nM).
|
| T6440 |
CGP 57380
|
522629-08-9
|
99.89%
|
|
|
CGP 57380 (MNK1 Inhibitor) is a potent MNK1 inhibitor with IC50 of 2.2 μM, exhibiting no inhibitory activity on p38, JNK1, ERK1 and -2, PKC, or c-Src-like kinase...
|
