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MRP

Multidrug resistance proteins (MRPs) are members of the C family of a group of proteins named ATP-binding cassette (ABC) transporters. These ABC transporters together form the largest branch of proteins within the human body. The MRP family comprises of 13 members, of which MRP1 to MRP9 are the major transporters indicated to cause multidrug resistance in tumor cells by extruding anticancer drugs out of the cell.
Cat. No. 製品名 CAS No. Purity Chemical Structure
T9982 PU23 817635-93-1 98%
PU 23 is an inhibitor of multidrug-resistant protein 4 (MRP4).
T19866 Indican 487-60-5
Indican (Indoxyl-β-D-glucoside) is a natural protective compound that is used to protect the liver.
T0839 Ketoprofen 22071-15-4 100%
Ketoprofen (RP-19583) is a propionic acid derivate and nonsteroidal anti-inflammatory drug (NSAID) with anti-inflammatory, analgesic and antipyretic effects. Ket...
T27954 LY-402913 334970-65-9 100%
LY-402913 is a selective multidrug resistance protein (MRP1) inhibitor.
T1130 Gramicidin 1405-97-6 97.03%
A group of peptide antibiotics from BACILLUS brevis. Gramicidin (Gramicidine) C or S is a cyclic, ten-amino acid polypeptide and gramicidins A, B, D are linear. ...
T1571 Estriol 50-27-1 97.48%
Estriol (Oestriol) is a hydroxylated metabolite of ESTRADIOL or ESTRONE that has a hydroxyl group at C3, 16-alpha, and 17-beta position. Estriol is a major urina...
T0291 Flurbiprofen 5104-49-4 98%
Flurbiprofen (dl-Flurbiprofen) is an anti-inflammatory analgesic and antipyretic of the phenylalkynoic acid series. It has been shown to reduce bone resorption i...
T0707L Cyclophosphamide 50-18-0 98.26%
Cyclophosphamide is an alkylating agent used in the treatment of several forms of cancer including leukemias, lymphomas and breast cancer.
T8596 Ceefourin 1 315702-40-0 98.4%
Ceefourin 1 is a highly selective multidrug resistance protein 4 (MRP4) inhibitor.
T1605 Enalapril 75847-73-3 99.47%
Enalapril is a dicarbocyl-containing peptide and angiotensin-converting enzyme (ACE) inhibitor with antihypertensive activity.
T1484 Perindoprilat 95153-31-4 99.48%
Perindoprilat (Perindoprilate) is an angiotensin-converting enzyme inhibitor.
T0791 Reserpine 50-55-5 99.6%
Reserpine (Serpalan) is an alkaloid found in the roots of Rauwolfia serpentina and R. vomitoria. Reserpine inhibits the uptake of norepinephrine into storage ves...
T9944 3-(9-Chloro-3-methyl-4-oxoisoxazolo[4,3-c]quinolin-5(4H)-yl)-N-(3,4,5-trimethoxyphenyl)benzeneacetamide 246238-55-1 99.62%
3-(9-Chloro-3-methyl-4-oxoisoxazolo[4,3-c]quinolin-5(4H)-yl)-N-(3,4,5-trimethoxyphenyl)benzeneacetamide inhibits multidrug resistance protein (MRP1).
T0707 Cyclophosphamide hydrate 6055-19-2 99.65%
Cyclophosphamide hydrate is a DNA alkylating agent, an inhibitor of DNA synthesis. Cyclophosphamide hydrate has antitumor and immunosuppressive activities.
T0450 Fluoxetine 54910-89-3 99.65%
Fluoxetine (LY-110140) is a highly specific serotonin uptake inhibitor and selective 5-hydroxytryptamine (5-HT) reuptake inhibitor. Fluoxetine has antidepressant...
T0866 Propafenone 54063-53-5 99.69%
Propafenone (Propafenonum) is only found in individuals that have used or taken this drug. It is an antiarrhythmia agent that is particularly effective in ventri...
TN1863 Licoisoflavone A 66056-19-7 99.71%
Licoisoflavone A (Phaseoluteone) is an MRP inhibitor and inhibits lipid peroxidation with an IC50 of 7.2 μM.
T1484L Perindopril erbumine 107133-36-8 99.8%
Perindopril erbumine (S9490-3) is the tert-butylamine salt of perindopril, the ethyl ester of a non-sulfhydryl angiotensin-converting enzyme (ACE) inhibitor with...
T0706 Lisinopril dihydrate 83915-83-7 99.87%
Lisinopril dihydrate (MK-521) is an orally bioavailable, long-acting angiotensin-converting enzyme (ACE) inhibitor with antihypertensive activity.
T1050 Prazosin hydrochloride 19237-84-4 99.87%
Prazosin hydrochloride (Vasoflex) reduces peripheral resistance and relaxes vascular smooth muscles as a selective adrenergic alpha-1 antagonist by a mechanism n...
PU23
T9982
PU 23 is an inhibitor of multidrug-resistant protein 4 (MRP4).
Indican
T19866
Indican (Indoxyl-β-D-glucoside) is a natural protective compound that is used to protect the liver.
Ketoprofen
T0839
Ketoprofen (RP-19583) is a propionic acid derivate and nonsteroidal anti-inflammatory drug (NSAID) with anti-inflammatory, analgesic and antipyretic effects. Ket...
LY-402913
T27954
LY-402913 is a selective multidrug resistance protein (MRP1) inhibitor.
Gramicidin
T1130
A group of peptide antibiotics from BACILLUS brevis. Gramicidin (Gramicidine) C or S is a cyclic, ten-amino acid polypeptide and gramicidins A, B, D are linear. ...
Estriol
T1571
Estriol (Oestriol) is a hydroxylated metabolite of ESTRADIOL or ESTRONE that has a hydroxyl group at C3, 16-alpha, and 17-beta position. Estriol is a major urina...
Flurbiprofen
T0291
Flurbiprofen (dl-Flurbiprofen) is an anti-inflammatory analgesic and antipyretic of the phenylalkynoic acid series. It has been shown to reduce bone resorption i...
Cyclophosphamide
T0707L
Cyclophosphamide is an alkylating agent used in the treatment of several forms of cancer including leukemias, lymphomas and breast cancer.
Ceefourin 1
T8596
Ceefourin 1 is a highly selective multidrug resistance protein 4 (MRP4) inhibitor.
Enalapril
T1605
Enalapril is a dicarbocyl-containing peptide and angiotensin-converting enzyme (ACE) inhibitor with antihypertensive activity.
Perindoprilat
T1484
Perindoprilat (Perindoprilate) is an angiotensin-converting enzyme inhibitor.
Reserpine
T0791
Reserpine (Serpalan) is an alkaloid found in the roots of Rauwolfia serpentina and R. vomitoria. Reserpine inhibits the uptake of norepinephrine into storage ves...
3-(9-Chloro-3-methyl-4-oxoisoxazolo[4,3-c]quinolin-5(4H)-yl)-N-(3,4,5-trimethoxyphenyl)benzeneacetamide
T9944
3-(9-Chloro-3-methyl-4-oxoisoxazolo[4,3-c]quinolin-5(4H)-yl)-N-(3,4,5-trimethoxyphenyl)benzeneacetamide inhibits multidrug resistance protein (MRP1).
Cyclophosphamide hydrate
T0707
Cyclophosphamide hydrate is a DNA alkylating agent, an inhibitor of DNA synthesis. Cyclophosphamide hydrate has antitumor and immunosuppressive activities.
Fluoxetine
T0450
Fluoxetine (LY-110140) is a highly specific serotonin uptake inhibitor and selective 5-hydroxytryptamine (5-HT) reuptake inhibitor. Fluoxetine has antidepressant...
Propafenone
T0866
Propafenone (Propafenonum) is only found in individuals that have used or taken this drug. It is an antiarrhythmia agent that is particularly effective in ventri...
Licoisoflavone A
TN1863
Licoisoflavone A (Phaseoluteone) is an MRP inhibitor and inhibits lipid peroxidation with an IC50 of 7.2 μM.
Perindopril erbumine
T1484L
Perindopril erbumine (S9490-3) is the tert-butylamine salt of perindopril, the ethyl ester of a non-sulfhydryl angiotensin-converting enzyme (ACE) inhibitor with...
Lisinopril dihydrate
T0706
Lisinopril dihydrate (MK-521) is an orally bioavailable, long-acting angiotensin-converting enzyme (ACE) inhibitor with antihypertensive activity.
Prazosin hydrochloride
T1050
Prazosin hydrochloride (Vasoflex) reduces peripheral resistance and relaxes vascular smooth muscles as a selective adrenergic alpha-1 antagonist by a mechanism n...
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