| T11917 |
Lys-SMCC-DM1
|
1281816-04-3
|
98%
|
|
|
DM1 is a tubulin inhibitor. Lys-SMCC-DM1 (Lys-Nε-MCC-DM1) is the active metabolite of DM1.
|
| T41248 |
Thiocolchicine
|
2730-71-4
|
98%
|
|
|
Thiocolchicine is an effective inhibitor of tubulin polymerization with an IC50 of 2.5 µM and a Ki of 0.7 µM. Thiocolchicine induces cell apoptosis. Thiocolchici...
|
| T2502 |
INH1
|
313553-47-8
|
98%
|
|
|
INH1 (IBT13131) is a cell-permeable Hec1 inhibitor that specifically disrupts the Hec1/Nek2 interaction.
|
| T60065 |
WAY-118959-A
|
315703-81-2
|
98%
|
|
|
WAY-118959-A is a potential microtubule acetylation inhibitor.
|
| T6888 |
Methylene Blue
|
61-73-4
|
98%
|
|
|
Methylene Blue (Tetramethylthionine chloride) (IC50 of 1.9 μM) inhibits tau filament formation. And it inhibits soluble guanylyl cyclase. It is also used as a dy...
|
| T76726 |
Zagotenemab
|
2019133-28-7
|
98%
|
Zagotenemab
|
|
Zagotenemab is a humanized antibody against the microtubule-associated protein tau that selectively regulates tau deposits in the brain. Zagotenemab can be used ...
|
| T74178 |
Glembatumumab vedotin
|
1182215-65-1
|
98%
|
|
|
Glembatumumab vedotin (CDX-011) is an antibody-activated small molecule coupling, Glembatumumab vedotin has potent anticancer effects and can be used in the stud...
|
| T2060 |
ELR510444
|
1233948-35-0
|
98%
|
|
|
ELR510444 (LR510444) is a novel microtubule disruptor; inhibits MDA-MB-231 cell proliferation with IC50 of 30.9 nM; not a substrate for the P-glycoprotein drug t...
|
| T18312 |
Mc-MMAE
|
863971-24-8
|
98%
|
|
|
Mc-MMAE (Maleimidocaproyl-monomethylauristatin E) is a drug-linker conjugate for ADC. Mc-MMAE is a maleimidocaproyl-conjugated monomethyl auristatin E, which is ...
|
| T21408 |
DM1-SMe
|
138148-68-2
|
98%
|
|
|
DM1-SMe (DM1-SSMe) is a potent inhibitor of maytansinoid microtubular. DM1-SMe is about 3 to 10-fold more potent than the parent drug Maytansine, with IC50s of 0...
|
| TP1180 |
Dolastatin 10
|
110417-88-4
|
98%
|
|
|
Dolastatin 10 (DLS 10) is a powerful peptide with antimitotic properties, effectively inhibiting tubulin polymerization.
|
| T39994 |
Sovilnesib
|
2410796-79-9
|
98%
|
|
|
Sovilnesib is a kinesin-like protein KIF18A inhibitor. Sovilnesib can be used for the cancer research.
|
| T0186 |
Docetaxel trihydrate
|
148408-66-6
|
|
|
|
Docetaxel trihydrate (RP-56976 Trihydrate) is an antineoplastic agent that has a unique mechanism of action as an inhibitor of cellular mitosis and that currentl...
|
| T13278 |
Valecobulin hydrochloride
|
1240321-53-2
|
|
|
|
Valecobulin hydrochloride (CKD-516 hydrochloride) is a potent inhibitor of β-tubulin polymerization. Valecobulin hydrochloride is a valine prodrug and a vascular...
|
| T28886 |
Suprafenacine
|
1477482-50-0
|
|
|
|
Suprafenacine (N'-[(E)-(4-methylphenyl)methylidene]-4,5,6,7-tetrahydro-1H-indazole-3-carbohydrazide) is a cell-permeable microtubule destabilizer that induces ce...
|
| T36850 |
Curvulin
|
19054-27-4
|
|
|
|
Curvulin is the active metabolite isolated from Paraphoma sp. VIZR 1.46. Curvularin inhibits iNOS expression and microtubule assembly.
|
| T13687 |
Eribulin mesylate
|
441045-17-6
|
|
|
|
Eribulin mesylate (E7389 mesylate) (E7389 mesylate) inhibits the proliferation of cancer cells by binding microtubule proteins and microtubules. Eribulin mesylat...
|
| T5007 |
Benproperine phosphate
|
19428-14-9
|
100%
|
|
|
Benproperine phosphate (Pirexyl phosphate) is a cough suppressant.
|
| T60757 |
SB-216
|
2756818-39-8
|
100%
|
|
|
SB-216 is able to be used for the research of cancer which is a potent inhibitor of tubulin polymerization. SB-216 exhibits strong antiproliferative potency in ...
|
| T22661 |
CHM-1
|
154554-41-3
|
100%
|
|
|
CHM-1 is an inducer of apoptosis, and displays potent antitumor ability in human hepatocellular carcinoma by activation of Cdc2 kinase activity. CHM-1 inhibits t...
|
