| T1768 |
7ACC2
|
1472624-85-3
|
100%
|
|
|
7ACC2 is a new potent MCT inhibitor with IC50 of 11 nM for [14C]-lactate influx; new antitumor treatment targeting lactate transport in Y cells.
|
| T5845 |
7ACC1
|
50995-74-9
|
98%
|
|
|
7ACC1 (D 142) selectively affects a single part of the MCT symporter translocation cycle, leading to strict inhibition of lactate influx. This singular activity ...
|
| T64378 |
AZD0095
|
2750001-23-9
|
98.26%
|
|
|
AZD0095 is a selective inhibitor of MCT4 with an IC50 of 1.3 nM.
|
| T14316 |
AR-C155858
|
496791-37-8
|
98.84%
|
|
|
AR-C155858 is an inhibitor of monocarboxylate transporter MCT1 and MCT2 (Kis: 2.3 nM and 10 nM).
|
| T67727 |
MCT1-IN-3
|
2878360-80-4
|
98.87%
|
|
|
MCT1-IN-3 is a monocarboxylate transporter 1 (MCT1) inhibitor. The solute carrier (SLC) monocarboxylate transporter 1 (MCT1; SLC16A1) represents a promising targ...
|
| T5208 |
BAY-8002
|
724440-27-1
|
99.13%
|
|
|
BAY-8002 is a potent dual MCT1/2 inhibitor (IC50 values are 3, 8, and 12 nM at rat (C6), human (DLD-1) and mouse (4T1) MCT1 respectively).
|
| T60165 |
VB124
|
2230186-18-0
|
99.21%
|
|
|
VB124 is an orally active, potent, and selective MCT4 inhibitor, demonstrating specificity in hindering lactate efflux, with IC50 values of 8.6 nM and 19 nM for ...
|
| T3210 |
AZD3965
|
1448671-31-5
|
99.75%
|
|
|
AZD3965 (AZD-3965) is a selective inhibitor of monocarboxylate transporter 1 (MCT1).
|
| T0689 |
D-Phenylalanine
|
673-06-3
|
99.77%
|
|
|
D-Phenylalanine, a necessary aromatic amino acid, is a precursor of thyroxine, dopamine, melanin, and noradrenaline (norepinephrine).
|
| T0693 |
Niflumic acid
|
4394-00-7
|
99.79%
|
|
|
Niflumic acid (Nifluril) is a Ca2+-activated Cl- channel blocker and an analgesic and anti-inflammatory agent used in the therapy of rheumatoid arthritis.
|
| T7460 |
α-Cyano-4-hydroxycinnamic acid
|
28166-41-8
|
99.8%
|
|
|
α-Cyano-4-hydroxycinnamic acid (α-Cyano-4-hydroxycinnamic acid(α-CHCA)) (α-CHCA) is an inhibitor of monocarboxylate transporter 1 (MCT1) that blocks pyruvate tra...
|
| T81962 |
Lactate transportor 1
|
|
98%
|
|
|
Lactate Transporter 1 (Compound 1) serves as an active lactate transporter within living cells and exerts cytotoxic effects, exhibiting IC50 values of 3.36 μM in...
|
