| T7134 |
Mavacamten
|
1642288-47-8
|
98%
|
|
|
Mavacamten (MYK-461) is an orally bioavailable inhibitor of cardiac myosin ATPase,( IC50s of 490, 711 nM for bovine cardiac and human cardiac, respectively)
|
| T72060 |
Myosin V-IN-1
|
1259177-59-7
|
97.31%
|
|
|
Myosin V-IN-1 is a potent and selective inhibitor of Myosin V with a Ki value of 6 μM.Myosin V-IN-1 inhibits actin V and slows down actin-activated myosin V ATPa...
|
| T7144 |
BTS
|
1576-37-0
|
98%
|
|
|
BTS (N-Tosylbenzylamine) is a potent inhibitor of Ca2+-stimulated myosin S1 ATPase (IC50 : 5 μM) .
|
| T67951 |
JB061
|
|
98.76%
|
|
|
JB061 is a nonmuscle myosin inhibitor, demonstrating selective inhibitory activity with IC50 values of 4.4 μM (Cardiac muscle myosin), 9.1 μM (Skeletal muscle my...
|
| T72023 |
JB002
|
30408-07-2
|
99.02%
|
|
|
JB002, a myosin II inhibitor, exhibits potent activity with an IC50 of ≤10 μM. It holds potential for research applications in muscle spasticity, chronic musculo...
|
| T24214 |
Phenamacril
|
39491-78-6
|
99.37%
|
|
|
Phenamacril (JS39919) is acyanoacrylate fungicide, has powerful inhibition against Fusarium species, especially to Fusarium graminearum. Phenamacril is a specifi...
|
| T67952 |
JB062
|
2417988-00-0
|
99.49%
|
|
|
JB062 is a chemical compound acting as a nonmuscle myosin inhibitor, exhibiting IC50 values of 1.6, 5.4, and >100 μM against skeletal muscle myosin, cardiac musc...
|
| T6038 |
(-)-Blebbistatin
|
856925-71-8
|
99.59%
|
|
|
(-)-Blebbistatin ((S)-(-)-Blebbistatin) is an S enantiomer of blebbistatin. It is a potent and selective myosin II inhibitor with IC50 ranging from 0.5 to 5 μM.
|
| T16104 |
ML-9
|
105637-50-1
|
99.6%
|
|
|
ML-9 suppresses MLCK, PKA, and PKC activity with Ki values of 4, 32, and 54 μM, respectively. ML-9 is a selective and effective inhibitor of Akt kinase, inhibits...
|
| T3050 |
ML-7 hydrochloride
|
110448-33-4
|
99.61%
|
|
|
ML-7 hydrochloride (ML-7 HCl) is a cell-permeable, reversible, effective, ATP-competitive, and specific inhibitor of myosin light chain kinase (Ki: 300 nM); also...
|
| T2006 |
Omecamtiv mecarbil
|
873697-71-3
|
99.62%
|
|
|
Omecamtiv mecarbil (CK-1827452) has been used in trials studying the treatment and basic science of Heart Failure, Echocardiogram, Pharmacokinetics, Chronic Hear...
|
| T7648 |
HA-100
|
84468-24-6
|
99.69%
|
|
|
HA-100 is an inhibitor of protein kinase
|
| T20792 |
W-7 hydrochloride
|
61714-27-0
|
99.75%
|
|
|
W-7 hydrochloride (W-7 HCl), a calmodulin antagonist, inhibits Ca2+-calmodulin-dependent myosin light chain kinase and phosphodiesterase, W-7 hydrochloride induc...
|
| T15050 |
Danicamtiv
|
1970972-74-7
|
99.75%
|
|
|
Danicamtiv (MYK-491) is an inotropic agent and it also is a selective allosteric activator of cardiac myosin. Danicamtiv increases cardiac systolic function and ...
|
| T21550 |
Blebbistatin
|
674289-55-5
|
99.88%
|
|
|
Blebbistatin ((±)-Blebbistatin) is a selective non-muscle myosin II (NMII) inhibitor. It promotes directional migration of corneal endothelial cells (CECs) and a...
|
| T12360 |
Para-Nitroblebbistatin
|
1621326-32-6
|
99.92%
|
|
|
para-Nitroblebbistatin (p-Nitroblebbistatin) is a non-cytotoxic, fluorescent, photostable and specific Myosin II inhibitor. para-Nitroblebbistatin can be used in...
|
| T80088 |
16-38-Thymosin β4 (cattle) (TFA)
|
|
98%
|
|
|
Thymosin β4 (cattle) TFA is a high-affinity activator of MLCK that operates independently of Ca2+ [1].
|
