| T30219 |
AVE-9488
|
291756-32-6
|
98%
|
|
|
AVE-9488 is a novel endothelial NO synthase (eNOS) enhancer that upregulates eNOS expression, induces NO production, and may ameliorate portal hypertension.
|
| T17056 |
Tetrahydrobiopterin
|
17528-72-2
|
98%
|
|
|
Tetrahydrobiopterin (BH4) is a cofactor for aromatic amino acid hydroxylases and an essential cofactor for nitric oxide synthase (NOS), which is used in the stud...
|
| TN3694 |
Coniferaldehyde
|
20649-42-7
|
98%
|
|
|
Coniferaldehyde can significantly inhibit the growth of viability of strains of Oenococcus oeni. Coniferaldehyde exerts anti-inflammatory properties by inducing ...
|
| TN1058 |
Pelargonidin chloride
|
134-04-3
|
98%
|
|
|
Pelargonidin chloride shows protective effect against CTN-induced oxidative stress in HepG2 cells and up-regulated the activity of detoxification enzyme levels t...
|
| T39020 |
Carboxyebselen
|
153871-75-1
|
98%
|
|
|
Carboxyebselen (HOOC-Ebs) is an endothelial nitric oxide synthase (eNOS) inhibitor that is potent and selective.
|
| T9955 |
EX-A5758
|
308277-46-5
|
98%
|
|
|
EX-A5758 is a novel putative small molecule nNOS-NOS1AP inhibitor, suppressing inflammatory nociception and chemotherapy-induced neuropathic pain and synergizes ...
|
| T10107 |
3-Bromo-7-nitroindazole
|
74209-34-0
|
98%
|
|
|
3-Bromo-7-nitroindazole is a more potent and selective inhibitor of neuronal nitric oxide synthase (nNOS) than eNOS or iNOS. It affects the intercellular messeng...
|
| T14149 |
AICAR phosphate
|
681006-28-0
|
98%
|
|
|
AICAR phosphate (Acadesine phosphate) is an AMPK activator and inhibitor of autophagy, YAP, and mitophagy, as well as an adenosine analog that regulates glucose ...
|
| T15697 |
L-NMMA acetate
|
53308-83-1
|
98%
|
|
|
L-NMMA acetate (Tilarginine acetate) is an inhibitor of nitric oxide synthase of all NOS isoforms (i.e. NOS1, NOS2, and NOS3). The Ki values are 0.18, 0.4, and 6...
|
| TN1599 |
Eburicoic acid
|
560-66-7
|
98%
|
|
|
Eburicoic acid (ZINC4655149) exhibits anti-inflammatory and antioxidant activity thereby protecting the liver from CCl4-induced hepatic damage and can be used in...
|
| T3426 |
Bacoside A
|
11028-00-5
|
|
|
|
Bacoside A has a possible anticancer activity that could be inducing cell cycle arrest and apoptosis through Notch pathway in GBM in vitro. It exerts cytoprotect...
|
| T22419 |
S-Methylisothiourea sulfate
|
867-44-7
|
|
|
|
S-Methylisothiourea sulfate ((S)-Methylisothiourea sulfate) is a potent and selective inhibitor of iNOS and exerts beneficial effects in rodent models of septic ...
|
| T7206L |
2-Iminobiotin hydrobromide
|
76985-52-9
|
|
|
|
2-Iminobiotin hydrobromide (Guanidinobiotin) is a cyclic guanidino analog of biotin that acts as a reversible inhibitor of inducible nitric oxide synthase (iNOS)...
|
| T3491 |
1400W dihydrochloride
|
214358-33-5
|
100%
|
|
|
1400W dihydrochloride (N-(3-(Aminomethyl)benzyl)acetamidine) is a highly effective and specific inhibitor of inducible NOS2 (iNOS).
|
| T21700 |
NOS-IN-1
|
165383-72-2
|
100%
|
|
|
NOS-IN-1 (2-Imino-4-methylpiperidine acetate) is a potent and orally active inhibitor of NO synthase (NOS) isoforms. NOS-IN-1 exhibits IC50s of 0.1 μM, 0.2 μM, a...
|
| T22724 |
Dimaprit dihydrochloride
|
23256-33-9
|
100%
|
|
|
Dimaprit dihydrochloride is a selective histamine H2 receptor agonist. Dimaprit dihydrochloride also inhibits nNOS with an IC50 of 49 μM. It can stimulate gastri...
|
| T0358 |
Aminoguanidine hydrochloride
|
1937-19-5
|
100%
|
|
|
Aminoguanidine hydrochloride (Hydrazinecarboximidamide) is a diamine oxidase and NO synthase inhibitor, used in the treatment of diabetic nephropathy.
|
| TN1576 |
Diallyl disulfide
|
2179-57-9
|
95%
|
|
|
Diallyl disulfide has antitumor effect, the effect can be enhanced by miR-200b and miR-22.
|
| T7474 |
7-Nitroindazole
|
2942-42-9
|
96.15%
|
|
|
7-Nitroindazole is a non-selective inhibitor of NOS isoforms in vitro for neuronal nitric oxide synthase showing a 10-fold selectivity for neuronal NOS.
|
| T11518L |
GW274150
|
210354-22-6
|
96.43%
|
|
|
GW274150 is an orally active, selective and potent dual inhibitor of NADPH-dependent human nitric oxide synthase (iNOS) (Kd=40 nM) and rat inducible nitric oxide...
|
