ホーム 計算ツール
代理店ログイン

NO Synthase

Nitric oxide synthases (NOSs) are a family of enzymes catalyzing the production of nitric oxide (NO) from L-arginine. NO is an important cellular signaling molecule. It helps modulate vascular tone, insulin secretion, airway tone, and peristalsis, and is involved in angiogenesis and neural development. It may function as a retrograde neurotransmitter. Nitric oxide is mediated in mammals by the calcium-calmodulin controlled isoenzymes eNOS (endothelial NOS) and nNOS (neuronal NOS). The inducible isoform, iNOS, involved in immune response, binds calmodulin at physiologically relevant concentrations, and produces NO as an immune defense mechanism, as NO is a free radical with an unpaired electron. It is the proximate cause of septic shock and may function in autoimmune disease.
Cat. No. 製品名 CAS No. Purity Chemical Structure
T30219 AVE-9488 291756-32-6 98%
AVE-9488 is a novel endothelial NO synthase (eNOS) enhancer that upregulates eNOS expression, induces NO production, and may ameliorate portal hypertension.
TN1058 Pelargonidin chloride 134-04-3 98%
Pelargonidin chloride shows protective effect against CTN-induced oxidative stress in HepG2 cells and up-regulated the activity of detoxification enzyme levels t...
T3779 Crocin II 55750-84-0 98%
Crocin II (Crocetin gentiobiosylglucosyl ester) has anti-inflammatory and anti-apoptotic effects against gastric ischemia-reperfusion injury in rats, the effect ...
TP2057L Camstatin acetate 98%
Camstatin acetate binds calmodulin and inhibits neuronal nitric oxide synthase. Camstatin acetate is a functionally active 25-residue fragment of the single calm...
T6888 Methylene Blue 61-73-4 98%
Methylene Blue (Tetramethylthionine chloride) (IC50 of 1.9 μM) inhibits tau filament formation. And it inhibits soluble guanylyl cyclase. It is also used as a dy...
TN2003 Obtucarbamate A 6935-99-5 98%
Obtucarbamate A isolated from Disporum cantoniense has antitussive activity.It has antitussive activity, it exhibits significant inhibitory effect against neuroi...
T74048 PAPA NONOate 146672-58-4 98%
PAPA NONOate is a pH-regulated NO donor.PAPA NONOate has potential antitumor activity and can be used to study diabetic wound healing disorders.
T74030 MAHMA NONOate 146724-86-9 98%
MAHMA NONOate is a pH-dependent NO donor.MAHMA NONOate inhibits collagen or ADP-induced platelet aggregation.
TN1624 Ethyl cinnamate 103-36-6 98%
Ethyl cinnamate has antifungal, and vasorelaxant effects. Ethyl cinnamate can lead to the damage of cell membrane system and metabolic disorder through inducing ...
T38248 2-Ethylpyrazine 13925-00-3 98%
2-Ethylpyrazine is present in roasted coffee beans and is a volatile compound .2-Ethylpyrazine induces vasodilation through the activity of endothelium-derived r...
TN4171 Grossamide 80510-06-1 98%
Grossamide (GSE) Grossamide is a lignan amide derived from thioguanosine.6-Thioguanosine (GSE) is a selective and potent miR-210 (miRNA-210) inhibitor.6-Thioguan...
T2980 Chondroitin sulfate 9007-28-7 98%
Chondroitin sulfate (Chonsurid) is extracted from shark bone;Store the product in sealed, cool and dry condition
TN1599 Eburicoic acid 560-66-7 98%
Eburicoic acid (ZINC4655149) exhibits anti-inflammatory and antioxidant activity thereby protecting the liver from CCl4-induced hepatic damage and can be used in...
TN2286 Tsugaric acid A 174391-64-1
Tsugaric acid A can significantly inhibit superoxide anion formation in fMLP/CB-stimulated rat neutrophils, it is also able to protect human keratinocytes agains...
T7682 Asymmetric dimethylarginine 30315-93-6
Asymmetric dimethylarginine is an endogenous inhibitor of nitric oxide synthase (NOS)
T25865 NG-Nitroarginine methyl ester 50903-99-6
NG-Nitroarginine methyl ester (ω-Nitroarginine methyl) is a non-selective nitric oxide synthase inhibitor. It has been utilized experimentally to induce hyperten...
T22419 S-Methylisothiourea sulfate 867-44-7
S-Methylisothiourea sulfate ((S)-Methylisothiourea sulfate) is a potent and selective inhibitor of iNOS and exerts beneficial effects in rodent models of septic ...
T7206L 2-Iminobiotin hydrobromide 76985-52-9
2-Iminobiotin hydrobromide (Guanidinobiotin) is a cyclic guanidino analog of biotin that acts as a reversible inhibitor of inducible nitric oxide synthase (iNOS)...
T4808 Agmatine sulfate 2482-00-0
Agmatine sulfate (Agmatine sulfate salt) is a bioactive metabolite of the arginine amino acid. It exerts modulatory action at multiple molecular targets, such as...
T3491 1400W dihydrochloride 214358-33-5 100%
1400W dihydrochloride (N-(3-(Aminomethyl)benzyl)acetamidine) is a highly effective and specific inhibitor of inducible NOS2 (iNOS).
AVE-9488
T30219
AVE-9488 is a novel endothelial NO synthase (eNOS) enhancer that upregulates eNOS expression, induces NO production, and may ameliorate portal hypertension.
Pelargonidin chloride
TN1058
Pelargonidin chloride shows protective effect against CTN-induced oxidative stress in HepG2 cells and up-regulated the activity of detoxification enzyme levels t...
Crocin II
T3779
Crocin II (Crocetin gentiobiosylglucosyl ester) has anti-inflammatory and anti-apoptotic effects against gastric ischemia-reperfusion injury in rats, the effect ...
Camstatin acetate
TP2057L
Camstatin acetate binds calmodulin and inhibits neuronal nitric oxide synthase. Camstatin acetate is a functionally active 25-residue fragment of the single calm...
Methylene Blue
T6888
Methylene Blue (Tetramethylthionine chloride) (IC50 of 1.9 μM) inhibits tau filament formation. And it inhibits soluble guanylyl cyclase. It is also used as a dy...
Obtucarbamate A
TN2003
Obtucarbamate A isolated from Disporum cantoniense has antitussive activity.It has antitussive activity, it exhibits significant inhibitory effect against neuroi...
PAPA NONOate
T74048
PAPA NONOate is a pH-regulated NO donor.PAPA NONOate has potential antitumor activity and can be used to study diabetic wound healing disorders.
MAHMA NONOate
T74030
MAHMA NONOate is a pH-dependent NO donor.MAHMA NONOate inhibits collagen or ADP-induced platelet aggregation.
Ethyl cinnamate
TN1624
Ethyl cinnamate has antifungal, and vasorelaxant effects. Ethyl cinnamate can lead to the damage of cell membrane system and metabolic disorder through inducing ...
2-Ethylpyrazine
T38248
2-Ethylpyrazine is present in roasted coffee beans and is a volatile compound .2-Ethylpyrazine induces vasodilation through the activity of endothelium-derived r...
Grossamide
TN4171
Grossamide (GSE) Grossamide is a lignan amide derived from thioguanosine.6-Thioguanosine (GSE) is a selective and potent miR-210 (miRNA-210) inhibitor.6-Thioguan...
Chondroitin sulfate
T2980
Chondroitin sulfate (Chonsurid) is extracted from shark bone;Store the product in sealed, cool and dry condition
Eburicoic acid
TN1599
Eburicoic acid (ZINC4655149) exhibits anti-inflammatory and antioxidant activity thereby protecting the liver from CCl4-induced hepatic damage and can be used in...
Tsugaric acid A
TN2286
Tsugaric acid A can significantly inhibit superoxide anion formation in fMLP/CB-stimulated rat neutrophils, it is also able to protect human keratinocytes agains...
Asymmetric dimethylarginine
T7682
Asymmetric dimethylarginine is an endogenous inhibitor of nitric oxide synthase (NOS)
NG-Nitroarginine methyl ester
T25865
NG-Nitroarginine methyl ester (ω-Nitroarginine methyl) is a non-selective nitric oxide synthase inhibitor. It has been utilized experimentally to induce hyperten...
S-Methylisothiourea sulfate
T22419
S-Methylisothiourea sulfate ((S)-Methylisothiourea sulfate) is a potent and selective inhibitor of iNOS and exerts beneficial effects in rodent models of septic ...
2-Iminobiotin hydrobromide
T7206L
2-Iminobiotin hydrobromide (Guanidinobiotin) is a cyclic guanidino analog of biotin that acts as a reversible inhibitor of inducible nitric oxide synthase (iNOS)...
Agmatine sulfate
T4808
Agmatine sulfate (Agmatine sulfate salt) is a bioactive metabolite of the arginine amino acid. It exerts modulatory action at multiple molecular targets, such as...
1400W dihydrochloride
T3491
1400W dihydrochloride (N-(3-(Aminomethyl)benzyl)acetamidine) is a highly effective and specific inhibitor of inducible NOS2 (iNOS).
1 2 3 4 5 6 7