Neurokinin receptor

The tachykinin receptor 1 (TACR1) also known as neurokinin 1 receptor (NK1R) or substance P receptor (SPR) is a G protein coupled receptor found in the central nervous system and peripheral nervous system. The endogenous ligand for this receptor is Substance P, although it has some affinity for other tachykinins.

Cat. No.	製品名	CAS No.	Purity
T23316	SB 218795	174635-53-1	98%
T23316	SB 218795 is an effective and selective antagonist of NK3 with a Ki 13 nM for hNK3 which is about 90-fold and 7000-fold selectivity over hNK2 and hNK1.
T14524	Befetupitant	290296-68-3	98%
T14524	Befetupitant (Ro67-5930) is a potent and selective tachykinin 1 receptor (NK1R) antagonist for the study of corneal neovascularization.
T24446L	MEN 10207 acetate		98%
T24446L	MEN 10207 acetate is a selective antagonist for NK-2 tachykinin receptor.
T17156	Tradipitant	622370-35-8	98%
T17156	Tradipitant (VLY-686) is an antagonist of neurokinin-1.
T38144	Elinzanetant	929046-33-3	98%
T38144	Elinzanetant is a dual antagonist of neurokinin (NK) receptors 1 and 3 and modulates reproductive hormone secretion.
T24697L	R 396 acetate		98%
T24697L	R 396 acetate is an NK-2 Tachykinin Receptor Antagonist.
T20413L	Spantide acetate	T20413L	98%
T20413L	Spantide acetate is a selective antagonist of NK1 receptor with Kis of 230 nM and 8150 nM for NK1 and NK2.
T19518L	Physalaemin acetate		98%
T19518L	Physalaemin acetate is a non-mammalian tachykinin with high affinity when binding selectively to neurokinin-1 (NK1) receptor.
TP1851L	Scyliorhinin II acetate	TP1851L	98%
TP1851L	Scyliorhinin II acetate is a selective agonist of the neurokinin-3 (NK3) receptor (Ki = 2.5 nM) in rat cerebral cortex.
T3716	Rolapitant	552292-08-7	98%
T3716	Rolapitant (SCH619734) Hydrochloride is the hydrochloride salt form of rolapitant, an orally bioavailable, centrally-acting, selective, neurokinin 1 receptor (NK...
TP1086	Men 10376 TFA(135306-85-3,free)	TP1086
TP1086	Men 10376 TFA(135306-85-3,free) (Neurokinin-2 receptor antagonist TFA) is an effective and selective tachykinin nk-2 receptor antagonist with a K I value of 4.4 ...
T69140	Burapitant	537034-22-3	100%
T69140	Burapitant (SSR 240600) is a novel non-peptide tachykinin neurokinin 1 (NK) receptor antagonist with anti-coke oven and antidepressant activity.
T7554	Substance P (7-11)	51165-05-0	100%
T7554	Substance P (7-11) (Substance P 7-11(TFA)) is a C-terminal fragment of Substance P .
T12000	MEN11467	214487-46-4	100%
T12000	MEN11467 is a novel, orally available, potent and selective peptidomimetic tachykinin NK 1 receptor antagonist for the study of acute colon cancer.
TP1883	[Lys5,MeLeu9,Nle10]-NKA(4-10)	137565-28-7	100%
TP1883	Highy selective and potent NK2 receptor agonist (IC50 = 6.1 nM). Induces contraction of the rat fundus and bladder (EC50 values are 117 and 10 nM respectively).
TP1008	Neurokinin A	86933-74-6	100%
TP1008	Neurokinin A (NKA), formerly known as Substance K, is a neurologically active peptide translated from the pre-protachykinin gene.
T7828	[Sar9,Met(O2)11]-Substance P	110880-55-2	100%
T7828	[Sar9,Met(O2)11]-Substance P (NA) is an agonist of NK1 receptor.
T8235	L-732138	148451-96-1	100%
T8235	L-732138 is a potent and competitive antagonist of neurokinin-1 (NK-1) receptor(IC50 : 2.3 nM)
TP1385	Neurokinin A(4-10) TFA(97559-35-8 free base)	TP1385	100%
TP1385	Neurokinin A(4-10) TFA(97559-35-8 free base) is a tachykinin NK2 receptor agonist[1].
TP1369L	[Sar9,Met(O2)11]-Substance P acetate	TP1369L	100%
TP1369L	[Sar9,Met(O2)11]-Substance P acetate is a tachykinin NK1 receptor selective agonist. [Sar9,Met(O2)11]-Substance P acetate is a selective tachykinin NK1 receptor ...