| TP1819L |
Substance P 1-9 aceate
|
|
98%
|
|
|
Substance P 1-9 aceate is nonapeptide, which decreases the inactivation of substance P by the guinea-pig ileum and urinary bladder.
|
| T77053 |
Latozinemab
|
|
98%
|
Latozinemab
|
|
Latozinemab (AL001) is a potent and selective recombinant humanized monoclonal antibody against Sortilin.Latozinemab has a high affinity for Sortilin and interru...
|
| T38807L |
[Lys8, Lys9]-Neurotensin (8-13) acetate
|
|
98%
|
|
|
[Lys8, Lys9]-Neurotensin (8-13) acetate, a Neurotensin analog, exerts its analgesic effects through activation of the G protein-coupled receptors NTS1 and NTS2, ...
|
| TP1310 |
Neurotensin
|
39379-15-2
|
100%
|
|
|
Neurotensin is a 13 amino acid neuropeptide that is implicated in the regulation of luteinizing hormone and prolactin release and has significant interaction wit...
|
| TP1116L |
Kinetensin acetate(103131-69-7 free base)
|
TP1116L
|
100%
|
|
|
Kinetensin acetate(103131-69-7 free base) is isolated from pepsin-treated human plasma. Kinetensin acetate(103131-69-7 free base) is a neurotensin-like peptide.
|
| T7617L |
Neurotensin(8-13) 3TFA(60482-95-3(free base))
|
2952825-79-3
|
100%
|
|
|
Neurotensin(8-13)(3TFA) is Neurotensin (NT) fragment, Neurotensin(8-13) results in a decrease in cell-surface NT1 receptors (NTR1) density.
|
| T12848 |
SB-657510
|
474960-44-6
|
98.03%
|
|
|
SB-657510 is a urotensin II (UII) receptor (UT) antagonist. The Ki values of UT for human, monkey, cat, rat and mouse were 61, 17, 30, 65 and 56 nM, respectively...
|
| TP2106L |
Urantide acetate(669089-53-6 free base)
|
TP2106L
|
99.22%
|
|
|
Urantide acetate is a selective and competitive urotensin-II (UT) receptor antagonist (pKB = 8.3). Blocks hU-II induced contractions in thoracic aorta ex vivo. E...
|
| T23323 |
SB 611812
|
345892-71-9
|
99.34%
|
|
|
SB 611812 is an antagonist of urotensin-II (UT) and can be used in studies about the treatment of cardiovascular disease.
|
| T22476 |
(±)-AC 7954 hydrochloride
|
477313-09-0
|
99.42%
|
|
|
(±)-AC 7954 hydrochloride is a urotensin-II (UT) receptor activator.
|
| TQ0086 |
AF38469
|
1531634-31-7
|
99.56%
|
|
|
AF38469 is a new, specific and orally bioavailable Sortilin inhibitor (IC50: 330 nM).
|
| T9044 |
SORT-PGRN interaction inhibitor 1
|
100957-85-5
|
99.56%
|
|
|
SORT-PGRN interaction inhibitor 1 is a potent sortilin-progranulin interaction inhibitor(IC50 of 2 μM).
|
| T28217 |
NTRC-844
|
1811503-67-9
|
99.61%
|
|
|
NTRC-844 is a selective rat neurotensin receptor type 2 (NTS2) antagonist that shows analgesic activity in animal models of pain.
|
| T16860 |
SBI-553
|
1849603-72-0
|
99.69%
|
|
|
SBI-553 is an effective and brain penetrant NTR1 allosteric modulator (EC50: 0.34 μM).
|
| TP2104L |
UFP 803 acetate
|
|
99.78%
|
|
|
UFP 803 acetate is a potent ligand of urotensin-II (UT) receptor. UFP-803 displays the activity of a lower residual agonist.
|
| TQ0075 |
ML314
|
1448895-09-7
|
98%
|
|
|
ML314 is an effective molecule agonist of NTR1 (EC50: 1.9 μM).
|
| T79106 |
SORT-PGRN interaction inhibitor 3
|
2691846-87-2
|
98%
|
|
|
SORT-PGRN Interaction Inhibitor 3 (Compound 13), with an IC50 value of 0.17 μM, acts as an inhibitor of the SORT-PGRN interaction, and is utilized in the study o...
|
| T79105 |
BVFP
|
357158-20-4
|
98%
|
|
|
BVFP exhibits affinity for the PGRN 588–593 peptide through binding with a dissociation constant (Kd) of 20 μM and is capable of disrupting the interaction betwe...
|
| T78954 |
HNTS1R agonist-1
|
|
98%
|
|
|
Compound 10, an hNTS1R agonist-1, acts as a full agonist with a strong affinity for hNTS1R (K i: 6.9 nM), showing the ability to cross the blood-brain barrier (B...
|
| T23386 |
SR 142948
|
184162-64-9
|
|
|
|
SR 142948 is a neurotensin (NT) receptor antagonist.
|
