| T9833 |
Opiranserin hydrochloride
|
1440796-75-7
|
98%
|
|
|
Opiranserin (VVZ-149) hydrochloride is a dual antagonist of glycine transporter type 2 (GlyT2) and serotonin receptor 2A (5HT2A), with IC50s of 0.86 and 1.3 μM, ...
|
| T16564 |
PPADS tetrasodium
|
192575-19-2
|
98%
|
|
|
PPADS tetrasodiuma is a potent P2X receptor antagonist and inhibitor of the inverse mode of Na/Ca²⁺ exchange in guinea pig airway smooth muscle and is neuroprote...
|
| T20731 |
Brilliant blue G-250
|
6104-58-1
|
98%
|
|
|
Brilliant blue G-250 (Acid blue 90, Coomassie Brilliant Blue G) is an antagonist of the P2X7 purinergic receptor.
|
| T3690 |
A-740003
|
861393-28-4
|
98%
|
|
|
A-740003 (A 740003) is an effective and specific P2X7 receptor antagonist (IC50: 18/40 nM, for rat/human). It can reduce nociception in animal models of persiste...
|
| T14076 |
A 839977
|
870061-27-1
|
98%
|
|
|
A 839977 is a selective P2X7 receptor antagonist with anti-inflammatory and analgesic activity that inhibits BzATP-induced calcium efflux from the P2X7 receptor ...
|
| T9786 |
Lu AF27139
|
2097117-06-9
|
98%
|
|
|
Lu AF27139 is an effective and selective antagonist of P2X7 receptor (IC50s of 12 and 2.4 nM for human and rat, Kis of 22, 54, and 13 nM for mouse, human, and ra...
|
| T14920 |
CE-224535
|
724424-43-5
|
98%
|
|
|
CE-224535 (PF-04905428) is a selective antagonist of P2X7 receptor. CE-224535 can be used in disease-modifying antirheumatic studies.
|
| T40045 |
Sivopixant
|
2414285-40-6
|
98%
|
|
|
Sivopixant (S-600918) (S-600918) is a potent and selective antagonist of P2X3 receptor (P2X3 IC 50 =4.2 nM; P2X2/3 IC 50 =1100 nM). Sivopixant shows strong analg...
|
| T1352 |
ATP disodium salt
|
987-65-5
|
98%
|
|
|
ATP disodium salt (Adenosine-Triphosphate) is a P2 purinoceptor agonist.
|
| T7805 |
GW791343 dihydrochloride
|
1019779-04-4
|
|
|
|
GW791343 dihydrochloride (GW791343 (HCl)) is a P2X7 allosteric modulator.
|
| T2673 |
A 438079 hydrochloride
|
899431-18-6
|
100%
|
|
|
A 438079 hydrochloride (A-438079 HCl) is a potent and selective P2X7 receptor antagonist with pIC50 of 6.9.
|
| T34081 |
Piromelatine
|
946846-83-9
|
100%
|
|
|
Piromelatine is an agonist of melatonin MT1/MT2 receptors, 5-HT1A and 5-HT1D, and an antagonist of 5-HT2B.Piromelatine has antinociceptive activity with inhibito...
|
| T37806 |
JNJ-55308942
|
2166558-11-6
|
100%
|
|
|
JNJ-55308942 is a selective and brain-penetrant antagonist of P2X7 functional with IC50s of 10 and 15 nM and Kis of 7.1 and 2.9 nM for hP2X7 and rP2X7, respectiv...
|
| T9653 |
(E/Z)-Sivopixant
|
1640808-39-4
|
100%
|
|
|
(E/Z)-Sivopixant ((E/Z)-S-600918)is a potent P2X3 receptor antagonist, IC50 = 4 nM. (E/Z)-Sivopixant can be used for respiratory diseases research.
|
| T7881 |
CTP disodium dihydrate
|
81012-87-5
|
100%
|
|
|
CTP disodium dihydrate is an agonist of P2X4 purinergic receptor
|
| T2806 |
Lappaconitine
|
32854-75-4
|
92.57%
|
|
|
Lappaconitine ((+)-Lappaconitine), isolated from Aconitum sinomontanum Nakai, was characterized as an analgesic.
|
| T8333 |
Aurintricarboxylic acid
|
4431-00-9
|
95%
|
|
|
Aurintricarboxylic acid (NSC-4056) is a strong inhibitor of topoisomerases and other nucleases. It is a potent inhibitor of ribonuclease and topoisomerase II by ...
|
| T8635 |
CI 75300
|
94875-80-6
|
95.00%
|
|
|
CI 75300 targets the P2X purinoceptor 7 (human).
|
| T1131 |
Ivermectin
|
70288-86-7
|
95.35%
|
|
|
Ivermectin (MK-933) is a glutamate-gated chloride channel (GluCls) activator, with antiparasitic activity.
|
| TQ0002 |
A-317491
|
475205-49-3
|
96.1%
|
|
|
A-317491 (ABT 202) is a non-nucleotide P2X3 ( Ki: 22 nM) and P2X2/3 receptor (Ki: 9 nM) antagonist, which inhibits calcium flux mediated by the receptors.
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