| TN2883 |
3',4'-Dimethoxyflavone
|
4143-62-8
|
98%
|
|
|
3',4'-Dimethoxyflavone is a standard compound of flavonoids with numerous medicinal activities.
|
| T4472 |
NMS-P118
|
1262417-51-5
|
98%
|
|
|
NMS-P118 is a potent, selective and orally available Inhibitor of PARP-1 for cancer therapy.
|
| T9756 |
AZD-9574
|
2756333-39-6
|
98%
|
|
|
AZD-9574 is a selective inhibitor of PARP1 at the sites of SSBs. AZD-9574 exhibits anti-cancer activities and can be used in studies about HRD+ breast cancer and...
|
| TN1651 |
Furanodiene
|
19912-61-9
|
98%
|
|
|
Furanodiene has anti-inflammatory and antioxidant activities, it is active against gram-positive bacteria and Candida albicans.
|
| T6892 |
Niraparib tosylate
|
1038915-73-9
|
|
|
|
Niraparib tosylate (MK-4827 (tosylate))(with IC50 of 3.8 nM/2.1 nM) is a selective PARP1/PARP2 inhibitor.
|
| T6578 |
ME0328
|
1445251-22-8
|
|
|
|
ME0328 is a potent and selective PARP inhibitor with IC50 of 0.89 μM for PARP3, about 7-fold selectivity over PARP1.
|
| T2105 |
Veliparib dihydrochloride
|
912445-05-7
|
|
|
|
Veliparib dihydrochloride (ABT-888 dihydrochloride) is a potent inhibitor of PARP1 and PARP2 with Ki of 5.2 nM and 2.9 nM in cell-free assays, respectively. It i...
|
| T6197 |
PJ34
|
344458-19-1
|
|
|
|
PJ34 HCl is the hydrochloride salt of PJ34, which is a PARP inhibitor with EC50 of 20 nM and is equally potent to PARP1/2.
|
| T9165 |
AZD5305
|
2589531-76-8
|
|
|
|
AZD5305 is a potent, selective and oral active PARP inhibitor.
|
| T3168 |
MN-64
|
92831-11-3
|
|
|
|
MN-64 is a tankyrases inhibitor, showed 6 nM potency against tankyrase 1, isoenzyme selectivity, and Wnt signaling inhibition.
|
| T50098 |
TIQ-A
|
420849-22-5
|
|
|
|
TIQ-A is a PARP1 inhibitor which involved in DNA single-strand break repair via the base excision repair pathway. PARP1 is triggered by DNA damage and its excess...
|
| T6941 |
PI-1840
|
1401223-22-0
|
100%
|
|
|
PI-1840（IC50 = 27 nM）is a reversible and selective chymotrypsin-like (CT-L) inhibitor, with little proteasome proteolytic effects on trypsin-like (T-L) and postg...
|
| T50044 |
5-AIQ
|
93117-08-9
|
95.00%
|
|
|
5-aminoisoquinolin-1(2H)-one is the inhibitor of calf thymus PARP1.
|
| T21524 |
4-amino-1,8-Naphthalimide
|
1742-95-6
|
95.13%
|
|
|
4-amino-1,8-Naphthalimide (4-ANI) is a PARP inhibitor with IC50 of 180 nM
|
| T9610 |
PARP1-IN-5 dihydrochloride
|
2823308-89-8
|
96.03%
|
|
|
PARP1-IN-5 dihydrochloride is an orally active, potent and selective PARP-1 inhibitor (IC50 =14.7 nM). PARP1-IN-5 dihydrochloride can be used for the research of...
|
| T67945 |
WAY-620473
|
743451-55-0
|
97.04%
|
|
|
WAY-620473 is a potent PARP-1 inhibitor with antitumor activity and alters eukaryotic lifespan.
|
| T4471 |
E7449
|
1140964-99-3
|
97.13%
|
|
|
E7449 (UNII-9X5A2QIA7C) is a potent PARP1 and PARP2 inhibitor and also inhibits TNKS1 and TNKS2, with IC50s of 2.0, 1.0, ～50 and ～50 nM for PARP1, PARP2, TNKS1 a...
|
| T3375 |
Verbascoside
|
61276-17-3
|
97.46%
|
|
|
Verbascoside (Kusaginin) is a protein kinase C inhibitor with antimicrobial, anti-inflammatory activities.
|
| T8296 |
5,7,4'-Trimethoxyflavone
|
5631-70-9
|
97.53%
|
|
|
5,7,4'-Trimethoxyflavone (4',5,7-Trimethoxyflavone) is isolated from Kaempferia parviflora (KP) which is a medicinal plant from Thailand.
|
| T6339 |
AG14361
|
328543-09-5
|
97.65%
|
|
|
AG14361 is an effective inhibitor of PARP1 (Ki<5 nM).
|
