T0070 |
Pentoxifylline
|
6493-05-6
|
98%
|
|
Pentoxifylline (PTX) modulates immunologic activity by stimulating cytokine production. Pentoxifylline is a methylxanthine derivative that inhibits phosphodieste...
|
T28352 |
PDE9-IN-(S)-C33
|
2066488-39-7
|
98%
|
|
PDE9-IN-(S)-C33 ((S)-C33) is a potent and selective inhibitor of PDE9 (IC50 = 11 nM). PDE9-IN-(S)-C33 can be used for central nervous system diseases and diabete...
|
T1112 |
2-(Hydroxymethyl)pyridine
|
586-98-1
|
98%
|
|
2-(Hydroxymethyl)pyridine (Piconol) is used as an organic synthesis and medicinal chemistry intermediate for the synthesis of the stimulant laxative bisacodyl, a...
|
T60105 |
Enpp-1-IN-14
|
2687222-59-7
|
98%
|
|
Enpp-1-IN-14 is a potent inhibitor of Ectonucleotide Pyrophosphatase/Phosphodiesterase-1 (ENPP1) with an IC50 value of 32.38 nM for recombinant human ENPP-1. Enp...
|
T62356 |
Mardepodect hydrochloride
|
2070014-78-5
|
98%
|
|
Mardepodect hydrochloride (Mardepodect HCl) is an orally active, selective and potent inhibitor of PDE10A that crosses the blood-brain barrier (IC50: 0.37 nM).Ma...
|
T0480 |
Doxofylline
|
69975-86-6
|
98%
|
|
Doxofylline (Doxophylline) is a methylxanthine derivative with the presence of a dioxolane group in position 7. As a drug used in the treatment of asthma, doxofy...
|
TN6988 |
Pterine-6-carboxylic acid
|
948-60-7
|
98%
|
|
Pterine-6-carboxylic acid (6-Carboxypterin) is a photodegradation product of folic acid, which can be used as a photosensitive agent to study the molecular mecha...
|
T7542 |
Amino Tadalafil
|
385769-84-6
|
98%
|
|
Amino tadalafil is a potent phosphodiesterase 5 (PDE5) inhibitor.
|
T4285 |
Crisaborole
|
906673-24-3
|
98%
|
|
Crisaborole (AN-2728) is a Phosphodiesterase 4 Inhibitor.
|
TP1909L1 |
CALP2 acetate(261969-04-4 free base)
|
TP1909L1
|
98%
|
|
CALP2 acetate is an antagonist of calmodulin showing high affinity for binding to the CaM EF-hand/Ca2+-binding site with a Kd of 7.9 µM. CALP2 acetate potently i...
|
T14958 |
Choline theophyllinate
|
4499-40-5
|
98%
|
|
Choline theophyllinate (Oxtriphylline) is the choline salt of theophylline, a small molecule PDE inhibitor that can be used to treat immune system disorders and ...
|
T60608 |
FPFT-2216
|
2367619-87-0
|
98%
|
|
FPFT-2216 is a "molecular glue" compound that degrades IKZF6, IKZF1, DE1D, and CK3α. FPFT-2216 has potential antitumor activity and can be used to study immune s...
|
TQ0126 |
Mirodenafil dihydrochloride
|
862189-96-6
|
98%
|
|
Mirodenafil dihydrochloride is a PDE-5 inhibitor developed for the treatment of erectile dysfunction.
|
T10545 |
BIO-32546
|
1548743-66-3
|
98%
|
|
BIO-32546 (S-isomer) is a highly potent regulator of autotaxin (ATX) with an IC50 value of 1 nM.
|
T12422 |
PF-04957325
|
1305115-80-3
|
98%
|
|
PF-04957325 is a potent and selective inhibitor of PDE8.PF-04957325 has an IC50 of 0.7 nM for PDE8A and 0.3 nM for PDE8B.PF-04957325 can be used to study autoimm...
|
T0264 |
Zomepirac sodium salt
|
64092-48-4
|
98%
|
|
Zomepirac sodium salt (McN-2783-21-98) is a prostaglandin synthetase inhibitor.
|
T71744 |
Imazodan
|
84243-58-3
|
98%
|
|
Imazodan, a small molecule compound with positive inotropic activity, is a selective type III phosphodiesterase inhibitor and can be used to study heart failure....
|
T14507 |
Bay 60-7550
|
439083-90-6
|
98%
|
|
Bay 60-7550 is a selective and potent PDE2 inhibitor (Ki: 3.8 nM) that exerts positive inotropic effects on rat heart by increasing PKA-mediated phosphorylation ...
|
T0383 |
Fenspiride hydrochloride
|
5053-08-7
|
98%
|
|
Fenspiride hydrochloride (Decaspiride) , an oxazolidinone spiro compound, is a drug used in the therapy of certain respiratory diseases. It is approved for use i...
|
T23154 |
Piclamilast
|
144035-83-6
|
98%
|
|
Piclamilast (RP 73401) is a PDE4 inhibitor.
|