| T15670 |
KT5823
|
126643-37-6
|
98%
|
|
|
KT5823 is a selective and potent cGMP-dependent protein kinase (PKG) inhibitor with inhibitory effects on PKA and PKC.KT5823 increases thyroid-stimulating hormon...
|
| T15374 |
Ipatasertib dihydrochloride
|
1396257-94-5
|
98%
|
|
|
Ipatasertib dihydrochloride (GDC-0068 dihydrochloride) is a highly selective and ATP-competitive inhibitor of pan-Akt (IC50s: 5, 18 and 8 nM for Akt1, Akt2 and A...
|
| T6747 |
8-Bromo-cAMP sodium salt
|
76939-46-3
|
98%
|
|
|
8-Bromo-cAMP sodium salt (8-Br-Camp sodium salt) is a long-acting derivative of cyclic AMP. It is an activator of cyclic AMP-dependent protein kinase（PKA）, but r...
|
| T8681 |
HA-1004 dihydrochloride
|
92564-34-6
|
|
|
|
HA-1004 dihydrochloride is an inhibitor of PKA, PKC, cGKI, MYLK, and calcium channel protein
|
| TP1876L |
CREBtide acetate(149155-45-3 free base)
|
TP1876L
|
|
|
|
CREBtide acetate is a synthetic substrate for PKA (Km=3.9 μM), which is based on the phosphorylation sequence in d-CREB (cAMP response element binding protein).
|
| T14072 |
A-443654
|
552325-16-3
|
|
|
|
A-443654 is a pan-Akt inhibitor. A-443654 has equal potency against Akt1, Akt2, or Akt3 within cells (Ki=160 pM).
|
| T6605 |
NH125
|
278603-08-0
|
|
|
|
NH125 is a selective eEF-2 kinase inhibitor with IC50 of 60 nM, >125-fold selectivity over PKC, PKA, and CaMKII, and also a potent histidine kinase inhibitor.
|
| T2356 |
Ro-3306
|
872573-93-8
|
|
|
|
RO-3306 is a selectivity ATP-competitive CDK1 inhibitor (Ki: 20 nM). The selectivity of RO-3306 for CDK1 is >15-fold higher than a diverse panel of human kinases...
|
| T3269 |
Metadoxine
|
74536-44-0
|
100%
|
|
|
Metadoxine (Metadoxil) is a neurotransmitter stimulant.
|
| TP1789L |
Malantide acetate(86555-35-3 free base)
|
TP1789L
|
100%
|
|
|
Malantide acetate is a dodecapeptide phosphorylated by cyclic AMP-dependent protein kinase (PKA), and increases PKA activity.Malantide is a synthetic peptide tha...
|
| T77570 |
AP-C2
|
682793-07-3
|
100%
|
|
|
AP-C2 is a potent small molecule guanosine 3',5'-cyclic monophosphate (cGMP)-dependent protein kinase II (cGKII) inhibitor with a pIC50 of 5.2 for cGKII.
|
| TN4114 |
Gardenin A
|
21187-73-5
|
95.15%
|
|
|
Gardenin A shows neurotrophic effects via activating MAPK/ERK, PKC, and PKA. Gardenin A exhibits antidepressant, anticonvulsant and anxiolytic effects.
|
| T21983L |
PKI 14-22 amide, myristoylated Acetate
|
T21983L
|
96.34%
|
|
|
PKI 14-22 amide, myristoylated Acetate inhibit cAMP-dependent protein kinase (PKA) and blocks hyperalgesia produced by spinal administration of 8-bromo-cAMP.
|
| T22833 |
H-9 dihydrochloride
|
116700-36-8
|
96.57%
|
|
|
H-9 dihydrochloride is a potent protein kinase (PKA) inhibitor.H-9 Dihydrochloride significantly reduces the excitatory response to 5-HT at low concentrations.H-...
|
| T16791 |
Rottlerin
|
82-08-6
|
97.41%
|
|
|
Rottlerin (NSC-56346) is a natural product purified from Mallotus Philippinensis and is a specific PKC inhibitor (IC50: PKCδ of 3-6 μM, PKCα,β,γ of 30-42 μM, PKC...
|
| T3498 |
CCG215022
|
1813527-81-9
|
97.46%
|
|
|
CCG215022 is a G protein-coupled receptor kinases (GRKs) inhibitor with IC50s of 0.15±0.07 μM, 0.38±0.06 μM and 3.9±1 μM for GRK2, 5 and 1, respectively.
|
| T39217 |
PKA-IN-1
|
179985-52-5
|
97.52%
|
|
|
PKA-IN-1 is a selective and potent cyclic AMP-dependent protein kinase (PKA) catalytic subunit (cAK) inhibitor (IC50: 0.03 μM).PKA-IN-1 can be used to study dise...
|
| T4661 |
PKG drug G1
|
374703-78-3
|
97.57%
|
|
|
PKG drug G1 targets PKG Iα C42. PKG drug G1 can couple to vasodilation and blood pressure lowering by a C42 PKG Iα-independent mechanism.
|
| TP1523 |
PKG inhibitor peptide TFA (82801-73-8 free base)
|
TP1523
|
98%
|
|
|
PKG inhibitor peptide TFA (82801-73-8 free base) is an inhibitor of ATP-competitive cGMP-dependent protein kinase (PKG).
|
| T24051 |
Exisulind
|
59973-80-7
|
98.08%
|
|
|
Exisulind (CP248) induces apoptosis through the activation of protein kinase G (PKG). Exisulind exhibits antineoplastic activity in solid tumour and haematologic...
|
