| T9256 |
N-Cyclohexyl-4-[1-(1-piperazinyl)-2,6-naphthyridin-3-yl]-2-pyridinamine
|
1071135-06-2
|
98%
|
|
|
N-Cyclohexyl-4-[1-(1-piperazinyl)-2,6-naphthyridin-3-yl]-2-pyridinamine is a novel 2,6-naphthyridine identified by high throughput screen (HTS) as a dual protein...
|
| TN3694 |
Coniferaldehyde
|
20649-42-7
|
98%
|
|
|
Coniferaldehyde can significantly inhibit the growth of viability of strains of Oenococcus oeni. Coniferaldehyde exerts anti-inflammatory properties by inducing ...
|
| T7790 |
Bisindolylmaleimide V
|
113963-68-1
|
98%
|
|
|
Bisindolylmaleimide V, a bisindolylmaleimide derivative, is an inactive of a kinase inhibitor.
|
| T13363 |
Y06137
|
2226534-49-0
|
98%
|
|
|
Y06137 is an effective and selective BET inhibitor with a Kd of 81 nM for BRD4(1) bromodomain. Y06137 can be used for research on the treatment of castration-res...
|
| TP1888L1 |
[Ala113]-MBP (104-118) acetate
|
TP1888L1
|
98%
|
|
|
[Ala113]MBP(104-118) acetate is an noncompetitive peptide inhibitors of protein kinase C (PKC), with IC50s ranging from 28-62 μM.
|
| T60109 |
Protein kinase inhibitor H-7
|
84477-87-2
|
98%
|
|
|
Protein kinase inhibitor H-7 (5-(2-methylpiperazine-1-sulfonyl)isoquinoline) is a potent inhibitor of protein kinase C (PKC) with a Ki of 6 μM. Protein kinase in...
|
| T77332 |
TV 3279
|
209394-29-6
|
98%
|
|
|
TV 3279 is a novel ChE-MAI inhibitor , and the neuroprotective properties depend on their ability to induce the anti-apoptotic proteins PKC, Bcl-2, Bcl-x, and SO...
|
| T13810 |
Palmitoylcarnitine chloride
|
6865-14-1
|
98%
|
|
|
Palmitoylcarnitine chloride (Palmitoyl DL-carnitine chloride) is a mitochondrial fatty acid oxidation intermediate that mediates intralipid cardioprotection.Palm...
|
| T35407 |
Ζ-Stat
|
3316-02-7
|
98%
|
|
|
ζ-Stat (NSC37044), a specific and atypical inhibitor of PKC-ζ with an IC50 of 5 μM, demonstrates the ability to inhibit proliferation and induce apoptosis in mel...
|
| T8681 |
HA-1004 dihydrochloride
|
92564-34-6
|
|
|
|
HA-1004 dihydrochloride is an inhibitor of PKA, PKC, cGKI, MYLK, and calcium channel protein
|
| T14072 |
A-443654
|
552325-16-3
|
|
|
|
A-443654 is a pan-Akt inhibitor. A-443654 has equal potency against Akt1, Akt2, or Akt3 within cells (Ki=160 pM).
|
| T6605 |
NH125
|
278603-08-0
|
|
|
|
NH125 is a selective eEF-2 kinase inhibitor with IC50 of 60 nM, >125-fold selectivity over PKC, PKA, and CaMKII, and also a potent histidine kinase inhibitor.
|
| T2356 |
Ro-3306
|
872573-93-8
|
|
|
|
RO-3306 is a selectivity ATP-competitive CDK1 inhibitor (Ki: 20 nM). The selectivity of RO-3306 for CDK1 is >15-fold higher than a diverse panel of human kinases...
|
| T17019 |
TCS 21311
|
1260181-14-3
|
|
|
|
TCS 21311 (NIBR3049) is an effective and highly selective inhibitor of JAK3 (IC50: 8 nM). TCS 21311 inhibits PKCα, PKCθ, and GSK3β (IC50s: 13, 68, and 3 nM, resp...
|
| T14943 |
CGP60474
|
164658-13-3
|
|
|
|
CGP60474 is an inhibitor of VEGFR-2 (IC50 = 84 nM) and an inhibitor of ATP-competitive PKC. CGP60474 is also a highly potent anti-endotoxemic agent and inhibits ...
|
| T6588 |
Mitoxantrone
|
65271-80-9
|
|
|
|
Mitoxantrone (mitozantrone) is an anthracenedione antibiotic with antineoplastic activity. Mitoxantrone intercalates into and crosslinks DNA, thereby disrupting ...
|
| TP1053L |
Protein Kinase C 19-31 acetate
|
TP1053L
|
100%
|
|
|
Protein Kinase C 19-31 acetate, a peptide inhibitor of protein kinase C (PKC), derived from the pseudo-substrate regulatory domain of PKCa (residues 19-31) with ...
|
| TP1789L |
Malantide acetate(86555-35-3 free base)
|
TP1789L
|
100%
|
|
|
Malantide acetate is a dodecapeptide phosphorylated by cyclic AMP-dependent protein kinase (PKA), and increases PKA activity.Malantide is a synthetic peptide tha...
|
| T4391 |
Syk Inhibitor II dihydrochloride
|
227449-73-2
|
100%
|
|
|
Spleen tyrosine kinase (Syk) is a non-receptor tyrosine kinase that, upon phosphorylation, binds to immunoreceptor tyrosine-based activation motifs of FcRγ chain...
|
| T8376 |
PKCβ inhibitor 1
|
257879-35-9
|
100%
|
|
|
PKCβ inhibitor 1 (KUN79359)(KUN79359) is a potent, selective and ATP-competitive inhibitor of PKC isozymes(IC50s of 21 and 5 nM for human PKCβ1 and PKCβ2, respec...
|
