| T5771 |
Hypocrellin A
|
77029-83-5
|
98%
|
|
|
Hypocrellin A is PKC inhibitor, has light-induced antitumor,antifungal and antiviral activities, it also exerts immunomodulatory effects on MHC-restricted presen...
|
| T83627 |
Pim-1 kinase inhibitor 8
|
916038-47-6
|
98%
|
|
|
Pim-1 kinase inhibitor 8 is a potent Pim-1 kinase inhibitor with anticancer activity and can effectively inhibit cell migration.Pim-1 kinase inhibitor 8 is cytot...
|
| T5817 |
PKC-theta inhibitor hcl
|
2253640-49-0
|
98%
|
|
|
PKC-theta inhibitor hcl is a selective PKC-θinhibitor(IC50:12 nM).
|
| T22650 |
CGP 53353
|
145915-60-2
|
98%
|
|
|
CGP 53353 (DAPH-7) is a PKC inhibitor with inhibitory effects on PKCβII and PKCβI and can be used to study atherosclerosis.
|
| T8681 |
HA-1004 dihydrochloride
|
92564-34-6
|
|
|
|
HA-1004 dihydrochloride is an inhibitor of PKA, PKC, cGKI, MYLK, and calcium channel protein
|
| T3060 |
Fasudil hydrochloride
|
105628-07-7
|
|
|
|
Fasudil hydrochloride (HA-1077) is a potent inhibitor of ROCK1, PKA, PKC, and MLCK with Ki of 0.33 μM, 1.0 μM, 9.3 μM and 55 μM, respectively.
|
| T2356 |
Ro-3306
|
872573-93-8
|
|
|
|
RO-3306 is a selectivity ATP-competitive CDK1 inhibitor (Ki: 20 nM). The selectivity of RO-3306 for CDK1 is >15-fold higher than a diverse panel of human kinases...
|
| T17019 |
TCS 21311
|
1260181-14-3
|
|
|
|
TCS 21311 (NIBR3049) is an effective and highly selective inhibitor of JAK3 (IC50: 8 nM). TCS 21311 inhibits PKCα, PKCθ, and GSK3β (IC50s: 13, 68, and 3 nM, resp...
|
| T16791 |
Rottlerin
|
82-08-6
|
|
|
|
Rottlerin (NSC-56346) is a natural product purified from Mallotus Philippinensis and is a specific PKC inhibitor (IC50: PKCδ of 3-6 μM, PKCα,β,γ of 30-42 μM, PKC...
|
| TP1053L |
Protein Kinase C 19-31 acetate
|
TP1053L
|
100%
|
|
|
Protein Kinase C 19-31 acetate, a peptide inhibitor of protein kinase C (PKC), derived from the pseudo-substrate regulatory domain of PKCa (residues 19-31) with ...
|
| TP1789L |
Malantide acetate(86555-35-3 free base)
|
TP1789L
|
100%
|
|
|
Malantide acetate is a dodecapeptide phosphorylated by cyclic AMP-dependent protein kinase (PKA), and increases PKA activity.Malantide is a synthetic peptide tha...
|
| T4391 |
Syk Inhibitor II dihydrochloride
|
227449-73-2
|
100%
|
|
|
Spleen tyrosine kinase (Syk) is a non-receptor tyrosine kinase that, upon phosphorylation, binds to immunoreceptor tyrosine-based activation motifs of FcRγ chain...
|
| T8376 |
PKCβ inhibitor 1
|
257879-35-9
|
100%
|
|
|
PKCβ inhibitor 1 (KUN79359)(KUN79359) is a potent, selective and ATP-competitive inhibitor of PKC isozymes(IC50s of 21 and 5 nM for human PKCβ1 and PKCβ2, respec...
|
| T7885 |
Afuresertib hydrochloride
|
1047645-82-8
|
100%
|
|
|
Afuresertib hydrochloride is an inhibitor of Akt kinase (Kis of 0.08/2/2.6 nM for Akt1/Akt2/Akt3 respectively)
|
| TP1924L1 |
ZIP acetate(863987-12-6 free base)
|
TP1924L1
|
94.68%
|
|
|
ZIP acetate is a novel, cell-permeable inhibitor of protein kinase Mζ (PKMζ), a constitutively active, atypical PKC isozyme involved in LTP maintenance. Selectiv...
|
| TP1955L |
PKC β pseudosubstrate acetate
|
|
95.01%
|
|
|
PKC β pseudosubstrate acetate (PKC β pseudosubstrate acetate (172308-76-8 Free base)) is a selective cell-permeable inhibitor of PKC.
|
| TN4114 |
Gardenin A
|
21187-73-5
|
95.15%
|
|
|
Gardenin A shows neurotrophic effects via activating MAPK/ERK, PKC, and PKA. Gardenin A exhibits antidepressant, anticonvulsant and anxiolytic effects.
|
| T6515 |
Go6976
|
136194-77-9
|
95.89%
|
|
|
Go6976 is a small molecule inhibitor of protein kinase C (PKC). Go6976 has been widely used in biomedical research as a tool to study the role of PKC in various ...
|
| T3S1416 |
Decursin
|
5928-25-6
|
97.22%
|
|
|
1. Decursin (Decursinol angelate) is able to attenuate kainic acid-induced seizures and could have potential as an antiepileptic drug. 2. Decursin exhibits hepat...
|
| T7604 |
Valrubicin
|
56124-62-0
|
97.41%
|
|
|
Valrubicin (AD-32) (AD 32) inhibits TPA- and PDBu-induced PKC activation (IC50s: 0.85 and 1.25 μM) and has antitumor and anti-inflammatory activity.
|
