| T12835 |
Saroglitazar
|
495399-09-2
|
98%
|
|
|
Saroglitazar (Lipaglyn) is an agonist of PPAR with EC50 values of 0.65 pM and 3 nM for PPARα and PPARγ.
|
| TN1804 |
Isosilybin A
|
142796-21-2
|
98%
|
|
|
Isosilybin A is a partial PPARγ agonist, it significantly induced ABCA1 protein expression, it inhibited both monophenolase (IC50=1.7-7.6μM) and diphenolase (IC5...
|
| T9766 |
GW590735
|
343321-96-0
|
98%
|
|
|
GW590735 is an effective and selective PPARα agonist with an EC50 of 4 nM on PPARα and at least 500-fold selectivity versus PPARδ and PPARγ. GW590735 can be used...
|
| T22708 |
Darglitazone
|
141200-24-0
|
98%
|
|
|
Darglitazone (CP-86325) is a potent, selective agonist of PPAR-γ with antidiabetic actions. Darglitazone is effective in controlling blood glucose and lipid meta...
|
| TN4583 |
Moringin
|
73255-40-0
|
98%
|
|
|
Moringin is an isothiocyanate obtained from myrosinase-mediated hydrolysis of the glucosinolate precursor glucoMoringin present in Moringa oleifera seeds. Moring...
|
| T3056 |
Bavachinin
|
19879-30-2
|
|
|
|
Bavachinin (Bavachinin A)(7-O-Methylbavachin) is a natural compound isolated from the Chinese herb Fructus Psoraleae with potent anti-angiogenic activity.
|
| T9808 |
Tetradecylthioacetic acid
|
2921-20-2
|
|
|
|
Tetradecylthioacetic acid is a synthetic fatty acid with a sulfur substitution in the β-position. This modification renders TTA unable to undergo complete β-oxid...
|
| T7159 |
L-165041
|
79558-09-1
|
|
|
|
L-165041 is a potent and selective agonist of the nuclear receptor PPARβ and PPARδ(Ki = 9 nM, EC50 = ~500 nM ,respectively)
|
| T10900 |
CUDA
|
479413-68-8
|
|
|
|
CUDA is an effective soluble cyclohydrolase inhibitor with IC50 of 11.1 nM and 112 nM for mouse sEH and human sEH, respectively. CUDA selectively increases the a...
|
| T39516 |
Bocidelpar
|
2095128-20-2
|
|
|
|
Bocidelpar is a modulator of PPARδ with an EC50 of 7.80 nM and improves mitochondrial biogenesis and function in Duchenne Muscular Dystrophy muscle cells.
|
| T16074 |
Mifobate
|
76541-72-5
|
100%
|
|
|
Mifobate (SR-202) is a potent and specific antagonist of PPARγ. Mifobate shows antiobesity, antidiabetic and antiatherosclerotic effects[1].
|
| T11339 |
Furegrelate sodium
|
85666-17-7
|
100%
|
|
|
Furegrelate sodium (U-63557A) is a selective thromboxane synthase inhibitor with oral activity. Furegrelate sodium(U-63557A) inhibits thromboxane A2 (TXA2) synth...
|
| T0448 |
(S)-(+)-Ibuprofen
|
51146-56-6
|
100%
|
|
|
(S)-(+)-Ibuprofen (Dexibuprofen) , is a non-steroidal anti-inflammatory drug (NSAID), inhibiting cyclooxygenase (COX).
|
| T3000 |
Magnolol
|
528-43-8
|
100%
|
|
|
Magnolol (5,5'-Diallyl-2,2'-biphenyldiol) is a dual agonist of RXRα( EC50=10.4 μM) and PPARγ(EC50=17.7 μM). It blocks TNF-α-induced NF-KB activation.
|
| T7821 |
DG172 dihydrochloride
|
1361504-77-9
|
100%
|
|
|
DG172 dihydrochloride (DG-172 dihydrochloride) is an antagonist of PPARβ/δ(IC50 : 27 nM).
|
| T11339L |
Furegrelate
|
85666-24-6
|
100%
|
|
|
FUREGRELATE, a thromboxane A2 (TxA2) synthase inhibitor, blunts the development of pulmonary arterial hypertension in neonatal piglets.
|
| T6926 |
Palmitoylethanolamide
|
544-31-0
|
100%
|
|
|
Palmitoylethanolamide (Impulsin) is an endogenously fatty acid amide. It has a role as an anti-inflammatory drug, an antihypertensive agent, a neuroprotective ag...
|
| T15440 |
GSK376501A
|
1010412-80-2
|
100%
|
|
|
GSK376501A is a selective and effective modulator of peroxisome proliferator-activated receptor γ (PPARγ) for the study of type 2 diabetes.
|
| T22596 |
BADGE
|
1675-54-3
|
85.3%
|
|
|
PPARγ antagonist
|
| T3090 |
Abietic Acid
|
514-10-3
|
92.6%
|
|
|
Abietic Acid (Sylvic acid) is the primary component of resin acid isolated from rosin.
|
