| T9601 |
Tepotinib hydrochloride(1 : x)
|
1103508-80-0
|
98%
|
|
|
Tepotinib hydrochloride(1 : x) is an orally bioavailable, mesenchymal-epithelial transition (MET) TKI developed mainly for selected NSCLC patients with METex14 s...
|
| T2S1120 |
Ganoderenic acid B
|
100665-41-6
|
98%
|
|
|
Ganoderenic acid B, a natural product derived from Ganoderma lucidum, can work by inhibiting the transport function of ABCB1 and enhancing the cytotoxicity of ch...
|
| T12540 |
Pristinamycin IA
|
3131-03-1
|
98%
|
|
|
Pristinamycin IA (Mikamycin B) is a substrate for the P-glycoprotein and a cyclo-peptidic macrolactone antibiotic.
|
| T12341 |
P-gp inhibitor 1
|
2050747-49-2
|
98%
|
|
|
P-gp inhibitor 1 inhibits reversing P-glycoprotein-mediated multidrug resistance with an EC50 of 57.9 nM (K562/A02 cells).
|
| TN1425 |
Bacoside A3
|
157408-08-7
|
98%
|
|
|
Bacoside A3 has antioxidant potential, it shows comparatively higher neuroprotective response analysed as higher cell viability and decreased intracellular ROS.
|
| TN1651 |
Furanodiene
|
19912-61-9
|
98%
|
|
|
Furanodiene has anti-inflammatory and antioxidant activities, it is active against gram-positive bacteria and Candida albicans.
|
| T60009 |
YS-370
|
2470908-79-1
|
98%
|
|
|
YS-370 is an orally active inhibitor of P-gp and shows moderate inhibition against CYP3A4. YS-370 effectively reverses multidrug resistance to paclitaxel and col...
|
| T4059 |
Selamectin
|
220119-17-5
|
|
|
|
Selamectin (UK-124114) is a macrocyclic lactone derivative of ivermectin, an anthelmintic that potentiates glutamate- and GABA-gated chloride channel opening in ...
|
| T2893 |
Muscone
|
541-91-3
|
|
|
|
Muscone (3-Methylcyclopentadecanone) is an organic compound that is the primary contributor to the odor of musk.
|
| T4034 |
Solamargine
|
20311-51-7
|
|
|
|
Solamargine (δ-Solanigrine) is a major steroidal alkaloid glycoside extracted from a traditional Chinese medicine herb, Solanum nigrum L. (SNL); has been shown t...
|
| T3S0012 |
Coniferyl ferulate
|
63644-62-2
|
|
|
|
Coniferyl ferulate is a strong inhibitor of glutathione S-transferase (GST) isolated from Radix Angelicae sinensis. It shows strong inhibition of human placental...
|
| T0351 |
Risperidone
|
106266-06-2
|
100%
|
|
|
Risperidone (R 64 766) is a selective blocker of dopamine D2 receptors and serotonin 5-HT2 receptors that act as an atypical antipsychotic agent.
|
| T1222 |
Trifluoperazine dihydrochloride
|
440-17-5
|
100%
|
|
|
Trifluoperazine dihydrochloride (SKF5019) is a potent dopamine D2 receptor inhibitor used as an antipsychotic and an antiemetic.
|
| T3002 |
Piperine
|
94-62-2
|
100%
|
|
|
Piperine (Bioperine) , a alkaloid, has been used in trials studying the treatment of multiple myeloma and deglutition disorders.
|
| T0012 |
Cinchonine
|
118-10-5
|
86.31%
|
|
|
Cinchonine (LA40221), a local anesthetic of the amide type, now generally used for surface anesthesia. It is one of the most potent and toxic of the long-acting ...
|
| TN4761 |
Phellamurin
|
52589-11-4
|
93.19%
|
|
|
Phellamurin inhibits intestinal P-glycoprotein in a dose-dependent manner, there is a serious interaction occurred between Phellamurin with cyclosporin, to ensur...
|
| T17216 |
Valspodar
|
121584-18-7
|
95%
|
|
|
Valspodar (PSC 833) is a specific P-glycoprotein inhibitor and MDR regulator often used as a chemical sensitizer to study advanced epithelial ovarian cancer.
|
| T30260 |
AZD-5672
|
780750-65-4
|
95.58%
|
|
|
AZD-5672 is an antagonist of CCR5 with an IC50 of 0.32 nM. AZD-5672 inhibits hERG cardiac ion channel binding and P-gp-mediated digoxin transport with IC50s of 7...
|
| TMA2270 |
Alisol F 24-acetate
|
443683-76-9
|
96.33%
|
|
|
Alisol F 24-acetate is a natural product isolated from Alisma plantago-aquatica Linn[1]. Alisol F 24 Acetate enhances chemosensitivity and apoptosis of MCF-7/DOX...
|
| T13383 |
Zamicastat
|
1080028-80-3
|
97.43%
|
|
|
Zamicastat (BIA 5-1058) is an inhibitor of dopamine β-hydroxylase (DBH), and is also a concentration-dependent dual inhibitor of P-gp and BCRP(IC50 values of 73....
|
