| T12477 |
Uzansertib phosphate
|
2088852-47-3
|
98%
|
|
|
Uzansertib phosphate (INCB053914 phosphate) is an orally active, ATP-competitive inhibitor of pan-PIM kinase(PIM1, PIM2, PIM3 with IC50s of 0.24 nM, 30 nM, 0.12 ...
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| T1834 |
CX-6258
|
1202916-90-2
|
98%
|
|
|
CX-6258 is an orally valid Pim 1/2/3 kinase(IC50=5 nM/25 nM/16 nM) inhibitor. It has good biological activity and kinase specificity.
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| T77526 |
Pim-1 kinase inhibitor 4
|
|
98%
|
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Pim-1 kinase inhibitor 4 is a potent Pim-1 kinase inhibitor with an IC50 value of 17.01 nM.Pim-1 kinase inhibitor 4 also possesses antioxidant activity and poten...
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| T83627 |
Pim-1 kinase inhibitor 8
|
916038-47-6
|
98%
|
|
|
Pim-1 kinase inhibitor 8 is a potent Pim-1 kinase inhibitor with anticancer activity and can effectively inhibit cell migration.Pim-1 kinase inhibitor 8 is cytot...
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| T3352 |
XL413
|
1169558-38-6
|
100%
|
|
|
XL-413 is an orally bioavailable cell division cycle 7 homolog (CDC7) kinase inhibitor with potential antineoplastic activity. XL-413 binds to and inhibits the a...
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| T2300 |
AZD1208
|
1204144-28-4
|
97.24%
|
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AZD1208 is a novel, orally bioavailable, highly selective PIM kinase inhibitor with single nanomolar potency against all three PIM kinases.
|
| TQ0201 |
Hispidulin
|
1447-88-7
|
97.54%
|
|
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Hispidulin, a natural flavone with a broad spectrum of biological activities, is a Pim-1 inhibitor (IC50: 2.71 μM).
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| T4523 |
TP-3654
|
1361951-15-6
|
97.72%
|
|
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TP-3654 is a second-generation Pim kinase inhibitor (Ki values against Pim-1/3: 5/42 nM).
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| T5093 |
Pim1/AKK1-IN-1
|
1093222-27-5
|
97.84%
|
|
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Pim1/AKK1-IN-1 (LKB1/AAK1 dual inhibitor) is a potent multi-kinase inhibitor with Kd values of 35 nM/53 nM/75 nM/380 nM for Pim1/AKK1/MST2/LKB1 respectively, and...
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| T27704 |
K00135
|
869650-21-5
|
97.88%
|
|
|
K00135 (IMIDAZOPYRIDAZIN 1) is a selective inhibitor of Pim kinases and can be used in studies about gastric cancer and antileukemic therapeutics.
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| T6148 |
CX-6258 hydrochloride
|
1353859-00-3
|
97.98%
|
|
|
CX-6258 hydrochloride (Pim-Kinase Inhibitor X) is an effective, orally efficacious Pim1/2/3 kinase inhibitor (IC50: 5/25/16 nM).
|
| T15830 |
M-110
|
1395048-49-3
|
98.30%
|
|
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M-110 is a highly selective, ATP-competitive inhibitor of PIM kinases with a preference for PIM-3 (IC50=47 nM). M-110 inhibits PIM-1 and PIM-2 with similar IC50s...
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| T24152 |
HTH-01-091
|
2000209-42-5
|
98.40%
|
|
|
HTH-01-091 is a potent and selective maternal embryonic leucine zipper kinase (MELK) inhibitor (IC50: 10.5 nM).HTH-01-091 inhibits PIM1/2/3, RIPK2, DYRK3, smMLCK...
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| T10827 |
CK2/ERK8-IN-1
|
1085822-09-8
|
98.82%
|
|
|
CK2/ERK8-IN-1 (TMCB) is a dual inhibitor of casein kinase 2 (CK2) (Ki: 0.25 µM) and ERK8 (IC50s: 0.50 μM) with pro-apoptotic efficacy. CK2/ERK8-IN-1 also binds t...
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| T3078 |
SGI-1776
|
1025065-69-3
|
99.03%
|
|
|
SGI-1776 (Pim-Kinase Inhibitor IX) has been used in trials studying the treatment of Prostate Cancer, Non-Hodgkins Lymphoma, and Relapsed/Refractory Leukemias.
|
| T14779 |
BRD7389
|
376382-11-5
|
99.17%
|
|
|
BRD7389 is an inhibitor of RSK family kinase with IC50s of 1.5 μM, 2.4 μM, and 1.2 μM for RSK1, RSK2, and RSK3, respectively.
|
| T71339 |
BMS-863233 HCl
|
1169562-71-3
|
99.42%
|
|
|
BMS-863233 HCl is an ATP-competitive Cdc7 inhibitor (IC50: 3.4 nM) that is potent and selective.BMS-863233 HCl inhibited CK2 and PIM1 with IC50 values of 215 and...
|
| T3058 |
(Z)-SMI-4a
|
438190-29-5
|
99.44%
|
|
|
(Z)-SMI-4a (TCS PIM-1 4a) is a selective ATP-competitive Pim-1 kinase inhibitor with an IC50 of 21 nM.
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| T9583 |
HJ-PI01
|
6192-43-4
|
99.55%
|
|
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HJ-PI01 (HJ-PI01) is a Pim-2 inhibitor. HJ-PI01 (HJ-PI01) induces apoptosis and autophagic cell death in triple-negative human breast cancer.
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| T2253 |
TCS PIM-1 1
|
491871-58-0
|
99.64%
|
|
|
TCS PIM-1 1 (SC 204330)(sc-204330) is a effective and specific ATP-competitive Pim-1 kianse inhibitor (IC50: 50 nM) , exhibits good specific over MEK1/MEK2 and P...
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