| T29457L |
5-Hydroxydecanoate sodium
|
71186-53-3
|
98%
|
|
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5-Hydroxydecanoate sodium is a selective ATP-sensitive K+ (KATP) channel blocker with IC50 of about 30 μM. 5-Hydroxydecanoate sodium is a substrate for mitochon...
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| T1449 |
Hydrochlorothiazide
|
58-93-5
|
98%
|
|
|
Hydrochlorothiazide (HCTZ) is a Thiazide Diuretic. The physiologic effect of hydrochlorothiazide is by means of Increased Diuresis.
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| T31488 |
Dimethindene
|
5636-83-9
|
98%
|
|
|
Dimethindene (Dimetindeno) is a selective antagonist of H1 receptor and blocks K+ current. Dimethindene exhibits antihistamine and anticholinergic effects.
|
| T6587 |
Mitiglinide Calcium
|
145525-41-3
|
98%
|
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|
Mitiglinide Calcium (KAD-1229) is a blood glucose-lowering drugs, stimulating insulin secretion by closing the ATP-sensitive K+ channels in pancreatic beta-cells...
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| T12786 |
RY785
|
1393748-80-5
|
98%
|
|
|
RY785 is a potent and selective inhibitor of voltage-gated potassium channel such as KV2.2 (IC50 = 50 nM). RY785 may be used in pain relief studies.
|
| T1530 |
Mitiglinide calcium hydrate
|
207844-01-7
|
98%
|
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|
Mitiglinide calcium hydrate (S-21403 calcium hydrate) is a drug for the treatment of type 2 diabetes. Mitiglinide is thought to stimulate insulin secretion by cl...
|
| T1781 |
GW9508
|
885101-89-3
|
98%
|
|
|
GW9508(GW 9508) is a potent and selective agonist for FFA1 (GPR40), stimulates insulin secretion in a glucose-sensitive manner.
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| T16420 |
P-1075
|
60559-98-0
|
98%
|
|
|
P-1075 opens mitochondrial K(ATP) channels and generates reactive oxygen species causing cardioprotection of rabbit hearts. P-1075 is an effective activator of s...
|
| T15546 |
ICA
|
3374-88-7
|
98%
|
|
|
ICA (N-[4-(2-Pyridinyl)-2-thiazolyl]-2-pyridinamine) is a SK channel inhibitor and exhibits antileishmanial activity (IC50: 2.1 µM).
|
| T37709 |
2,2,2-Trichloroethanol
|
115-20-8
|
98%
|
|
|
2,2,2-Trichloroethanol, the active form of the sedative hypnotic drug chloral hydrate, is an agonist for the nonclassical K2P channels TREK-1 (KCNK2) and TRAAK (...
|
| T8391 |
Cesium chloride
|
7647-17-8
|
|
|
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Cesium chloride (CsCl) is considered to be the most toxic of the alkali chlorides, inhibiting fungal growth.
|
| T12478L |
Pinacidil
|
60560-33-0
|
|
|
|
Pinacidil (P 1134) is a guanidine that opens potassium channels and directly dilates peripheral blood vessels in small arteries, lowering blood pressure and peri...
|
| T0723 |
Cloperastine hydrochloride
|
14984-68-0
|
|
|
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Cloperastine hydrochloride (HT-11 hydrochloride) is a type of flavonoid.
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| T15545 |
ICA-27243
|
325457-89-4
|
|
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ICA-27243 is less effective at activating KCNQ4 and KCNQ3/Q5. ICA-27243 is a potent and orally active KCNQ2/Q3 potassium channel opener (EC50: 0.38 μM). ICA-2724...
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| T6245 |
BAPTA-AM
|
126150-97-8
|
|
|
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BAPTA-AM is a calcium chelator that is cell-permeable and selective, blocking hERG, hKv1.3, and hKv1.5 channels (IC50=1.3/1.45/1.23 μM). BAPTA-AM has a 105-fold ...
|
| T4612 |
NS309
|
18711-16-5
|
|
|
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NS309 is a nonselective activator of small- and intermediate-conductance Ca2+-activated K+ (SK/KCa2 and IK/KCa3.1) channels (EC50s range from 0.12-1.2 µM for SK ...
|
| T1320 |
Disopyramide
|
3737-09-5
|
100%
|
|
|
Disopyramide (Triombrin) is a class I anti-arrhythmic agent (one that interferes directly with the depolarization of the cardiac membrane and thus serves as a me...
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| T15143 |
DMP-543
|
160588-45-4
|
100%
|
|
|
DMP-543 (XR-543) is a potassium channel (KV7 channel) blocker that enhances the release of neurotransmitters.
|
| T0342 |
Carvedilol phosphate hemihydrate
|
610309-89-2
|
100%
|
|
|
Carvedilol phosphate hemihydrate (BM 14190 phosphate hemihydrate) is the phosphate salt form of carvedilol, a racemic mixture and adrenergic blocking agent with ...
|
| T1333 |
Tolazamide
|
1156-19-0
|
100%
|
|
|
Tolazamide (U-17835) is a sulphonylurea hypoglycemic agent with actions and uses similar to those of CHLORPROPAMIDE.
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