| T35610 |
2,5-dimethyl Celecoxib
|
457639-26-8
|
98%
|
|
|
2,5-dimethyl Celecoxib is a derivative of celecoxib that does not inhibit COX-2 (IC50 = >100 μM).1 It does inhibit microsomal prostaglandin E synthase-1 (mPGES-1...
|
| T15712 |
Laropiprant
|
571170-77-9
|
98%
|
|
|
Laropiprant (MK-0524) is a potent and selective antagonist of prostaglandin D2 (PGD2) receptor (DP) such as and DP/DP1 receptor(Ki = 0.57 nM) and TP Receptor(Ki ...
|
| T9622 |
MF-766
|
1050656-06-8
|
98%
|
|
|
MF-766 is a highly potent, selective and orally active EP4 antagonist with a Ki of 0.23 nM. It behaves as a full antagonist with an IC50 of 1.4 nM (shifted to 1....
|
| T69360 |
RO3244794
|
361457-01-4
|
98%
|
|
|
RO3244794 is a selective prostacyclin (IP) receptor antagonist that can be used to study liver injury.
|
| T15108 |
DG-041
|
861238-35-9
|
98%
|
|
|
DG-041 is an antagonist of high-affinity EP3 receptor (IC50s: 4.6 nM and 8.1 nM in the binding and FLIPR assay, respectively). DG-041 inhibits PGE2 facilitation ...
|
| T13703 |
Gestonorone Capronate
|
1253-28-7
|
98%
|
|
|
Gestonorone Capronate is a progesterone used to treat benign prostatic hyperplasia and endometrial cancer.
|
| T38369 |
CAY10678
|
1268709-57-4
|
98%
|
|
|
CAY10678 is an mPGES-1 inhibitor that inhibits PD-1.CAY10678 reduces collagen deposition and T-cell depletion, and may be used to study melanoma.CASHIPS
|
| T28958 |
TG6-129
|
1164464-14-5
|
98%
|
|
|
TG6-129 is an antagonist of the EP2 receptor. TG6-129 suppresses PGE2-induced elevation of cAMP in cells expressing EP2 with an IC50 value of 1.6 µM. TG6-129 red...
|
| T17232 |
Vidupiprant
|
1169483-24-2
|
98%
|
|
|
Vidupiprant (AMG 853) is an effective dual antagonist of CRTH2 and prostanoid D receptor with IC50s of 8 nM and 35 nM in human plasma. Vidupiprant can be used in...
|
| T23331 |
SC 51089
|
146033-02-5
|
98%
|
|
|
SC 51089 is a selective prostaglandin receptor PGE2 antagonist with selectivity for prostaglandin receptor subtypes and anti-injury activity that ameliorates mot...
|
| T5505 |
Terutroban
|
165538-40-9
|
98%
|
|
|
Terutroban, a thromboxane prostaglandin receptor antagonist, affects the progression of atherosclerosis.
|
| T7359 |
CAY10471 Racemate
|
844639-57-2
|
|
|
|
CAY10471 Racemate (TM30089 Racemate) is a potent, highly selective CRTH2/DP 2 receptor antagonist. CAY10471 Racemate binds to the human CRTH2/DP2, DP1, and TP re...
|
| T1338 |
Sucralfate
|
54182-58-0
|
|
|
|
Sucralfate (Sucrose octasulfate–aluminum complex) is a cytoprotective agent, an oral gastrointestinal medication primarily indicated for the treatment of active ...
|
| T4981 |
Anisotropine Methylbromide
|
80-50-2
|
|
|
|
Anisotropine Methylbromide is an anticholinergic agent and has been used for relief of gastrointestinal spasm and for the suppression of gastric acid secretion.
|
| T0002 |
Ethamsylate
|
2624-44-4
|
|
|
|
Ethamsylate (Dicynene) usually is used as a hemostatic drug, which increases capillary endothelial resistance and platelet adhesion, and inhibits biosynthesis an...
|
| T5171 |
Treprostinil Sodium
|
289480-64-4
|
|
|
|
Treprostinil Sodium (UT-15) is a potent DP1, IP and EP2 agonist (EC50: 0.6/1.9/6.2 nM).
|
| T22285 |
Carboprost
|
35700-23-3
|
|
|
|
Carboprost (15(S)-15-Methyl Prostaglandin F2α) is a synthetic prostaglandin analogue of PGF2α which has the effect of oxytocic. Carboprost is commonly used to re...
|
| T4635 |
Ralinepag
|
1187856-49-0
|
|
|
|
Ralinepag (APD811) is a potent, orally bioavailable agonist of non-prostanoid prostacyclin (IP) receptor, with EC50s of 8.5 nM, 530 nM and 850 nM for human and r...
|
| T6236 |
Ozagrel
|
82571-53-7
|
100%
|
|
|
Ozagrel (Domenan) is a selective thromboxane A(2) (TXA(2)) synthetase inhibitor with IC50 of 11 nM for rabbit platelet, used for the improvement of postoperative...
|
| T5841 |
Travoprost
|
157283-68-6
|
100%
|
|
|
Travoprost (Fluprostenol isopropyl ester) is used to treat glaucoma and ocular hypertension,is a potent and selective FP prostaglandin receptor agonist.
|
