T4436 |
RO1138452
|
221529-58-4
|
98%
|
|
RO1138452 (CAY10441) is a selective and orally bioavailable antagonist of prostacyclin receptor (pKi: 8.3). It antagonizes the carbaprostacyclin-induced activati...
|
T35610 |
2,5-dimethyl Celecoxib
|
457639-26-8
|
98%
|
|
2,5-dimethyl Celecoxib is a derivative of celecoxib that does not inhibit COX-2 (IC50 = >100 μM).1 It does inhibit microsomal prostaglandin E synthase-1 (mPGES-1...
|
T15712 |
Laropiprant
|
571170-77-9
|
98%
|
|
Laropiprant (MK-0524) is a potent and selective antagonist of prostaglandin D2 (PGD2) receptor (DP) such as and DP/DP1 receptor(Ki = 0.57 nM) and TP Receptor(Ki ...
|
T9622 |
MF-766
|
1050656-06-8
|
98%
|
|
MF-766 is a highly potent, selective and orally active EP4 antagonist with a Ki of 0.23 nM. It behaves as a full antagonist with an IC50 of 1.4 nM (shifted to 1....
|
TQ0290 |
ONO-AE3-208
|
402473-54-5
|
98%
|
|
ONO-AE3-208 (AE 3-208) is an EP4 antagonist. It suppresses cell migration, invasion, and metastasis of prostate cancer.
|
T15108 |
DG-041
|
861238-35-9
|
98%
|
|
DG-041 is an antagonist of high-affinity EP3 receptor (IC50s: 4.6 nM and 8.1 nM in the binding and FLIPR assay, respectively). DG-041 inhibits PGE2 facilitation ...
|
T4981 |
Anisotropine Methylbromide
|
80-50-2
|
98%
|
|
Anisotropine Methylbromide is an anticholinergic agent and has been used for relief of gastrointestinal spasm and for the suppression of gastric acid secretion.
|
T13703 |
Gestonorone Capronate
|
1253-28-7
|
98%
|
|
Gestonorone Capronate is a progesterone used to treat benign prostatic hyperplasia and endometrial cancer.
|
T0002 |
Ethamsylate
|
2624-44-4
|
98%
|
|
Ethamsylate (Dicynene) usually is used as a hemostatic drug, which increases capillary endothelial resistance and platelet adhesion, and inhibits biosynthesis an...
|
T5171 |
Treprostinil Sodium
|
289480-64-4
|
98%
|
|
Treprostinil Sodium (UT-15) is a potent DP1, IP and EP2 agonist (EC50: 0.6/1.9/6.2 nM).
|
T0795 |
Rutin
|
153-18-4
|
98%
|
|
Rutin (Quercetin 3-O-rutinoside), a flavonoid, has a variety of biological activities including antiallergic, anti-inflammatory, antiproliferative, and anticarci...
|
T16280 |
Nedocromil
|
69049-73-6
|
98%
|
|
Nedocromil (FPL 59002) inhibits the action or formation of multiple mediators. Which including histamine, leukotriene C4 (LTC4), and prostaglandin D2 (PGD2).
|
T28958 |
TG6-129
|
1164464-14-5
|
98%
|
|
TG6-129 is an antagonist of the EP2 receptor. TG6-129 suppresses PGE2-induced elevation of cAMP in cells expressing EP2 with an IC50 value of 1.6 µM. TG6-129 red...
|
T63667 |
ONO-8713
|
459411-08-6
|
98%
|
|
ONO-8713 is a selective prostaglandin E receptor subtype EP1 antagonist that can be used to study diseases of the biblical system and metabolism-related diseases...
|
T17232 |
Vidupiprant
|
1169483-24-2
|
98%
|
|
Vidupiprant (AMG 853) is an effective dual antagonist of CRTH2 and prostanoid D receptor with IC50s of 8 nM and 35 nM in human plasma. Vidupiprant can be used in...
|
T22285 |
Carboprost
|
35700-23-3
|
98%
|
|
Carboprost (15(S)-15-Methyl Prostaglandin F2α) is a synthetic prostaglandin analogue of PGF2α which has the effect of oxytocic. Carboprost is commonly used to re...
|
T5505 |
Terutroban
|
165538-40-9
|
98%
|
|
Terutroban, a thromboxane prostaglandin receptor antagonist, affects the progression of atherosclerosis.
|
TN1257 |
3-O-Acetyl-α-boswellic acid
|
89913-60-0
|
98%
|
|
3-O-Acetyl-α-boswellic acid (α-Boswellic acid acetate) has strong anti-inflammatory activity.
|
T4635 |
Ralinepag
|
1187856-49-0
|
98%
|
|
Ralinepag (APD811) is a potent, orally bioavailable agonist of non-prostanoid prostacyclin (IP) receptor, with EC50s of 8.5 nM, 530 nM and 850 nM for human and r...
|
T7359 |
CAY10471 Racemate
|
844639-57-2
|
|
|
CAY10471 Racemate (TM30089 Racemate) is a potent, highly selective CRTH2/DP 2 receptor antagonist. CAY10471 Racemate binds to the human CRTH2/DP2, DP1, and TP re...
|