T16012 |
Marizomib
|
437742-34-2
|
98%
|
|
Marizomib (ML858) is a novel irreversible brain-permeable proteasome inhibitor that inhibits CT-L (β5), CT-T-laspase-like (C-L, β1), and trypsin-like (T-L, β2) 2...
|
T7369L |
Gemigliptin Tartrate(911637-19-9 free base)
|
1374639-74-3
|
98%
|
|
Gemigliptin Tartrate (LC15-0444 tartrate) is a highly selective, reversible and competitive inhibitor of dipeptidyl peptidase-4 (DPP-4). It has an IC50 of 10.3 n...
|
T26754 |
BC-23
|
6298-15-3
|
98%
|
|
BC-23 (NSC 45382) is a potent proteasome inhibitor with antitumor and antimicrobial activity.BC-23 inhibits the CT-L activity of the proteasome and is used in th...
|
T36902 |
RA375
|
|
98%
|
|
RA375 is a inhibitor of RPN13 (26S proteasome regulatory subunit). RA375 activates UPR signaling, ROS production and apoptosis. RA375 exhibits ten-fold greater a...
|
T2401 |
Alogliptin Benzoate
|
850649-62-6
|
98%
|
|
Alogliptin Benzoate (SYR 322)(SYR 322), an effective and specific DPP-4 inhibitor (IC50<10 nM), exhibits greater than 10, 000-fold selectivity over DPP-8/9. Alog...
|
T2493 |
PD 151746
|
179461-52-0
|
98%
|
|
PD151746 is a calpain inhibitor with a 20-fold selectivity for u-calpain (Ki = 0.26 ± 0.03 μM) over m-calpain (Ki = 5.33 ± 0.77 μM). Its IC50 values are 0.26 ± 0...
|
T17011 |
TCH-165
|
1446350-60-2
|
98%
|
|
TCH-165 is a small molecule modulator of proteasome assembly, resulting in an increase in 20S levels. The increase in the level of free 20S corresponds to enhanc...
|
T16838 |
Saikogenin A
|
5092-09-1
|
98%
|
|
Saikogenin A is a dipeptidyl peptidase-4 inhibitor.
|
T3359 |
Aprotinin
|
9087-70-1
|
98%
|
|
Aprotinin (Traskolan) a broad-spectrum serine protease inhibitor, inhibiting the activity of a number of different esterases and proteases, including trypsin, ch...
|
T6432 |
Calpeptin
|
117591-20-5
|
98%
|
|
Calpeptin is a potent, cell-permeable calpain inhibitor.
|
T2296 |
Trelagliptin succinate
|
1029877-94-8
|
98%
|
|
Trelagliptin succinate (SYR-472 succinate) is a long-acting inhibitor of dipeptidyl peptidase-4 (DPP-4), being developed for the treatment of type 2 diabetes (T2...
|
T7369 |
Gemigliptin
|
911637-19-9
|
|
|
Gemigliptin (LC15-0444) is a potent dipeptidyl peptidase-4 (DPP-4) inhibitor(KD : 7.25 nM.)
|
T7814 |
Alloxan monohydrate
|
2244-11-3
|
|
|
Alloxan Monohydrate is a glucose analog used to induce diabetes by destroying beta-cells.
|
T2470 |
MDL-28170
|
88191-84-8
|
|
|
MDL-28170 (Calpain Inhibitor III) is a Cysteine protease.
|
T7133 |
Anagliptin
|
739366-20-2
|
100%
|
|
Anagliptin (SK-0403) is a potent Inhibitor of DPP-4(IC50 of 3.8 nM), for the treatment of type 2 diabetes mellitus.
|
T6999 |
Teneligliptin hydrobromide
|
906093-29-6
|
100%
|
|
Teneligliptin hydrobromide (MP-513 (hydrobromide)) is a novel, potent, and long-lasting dipeptidyl peptidase-4 inhibitor; competitively inhibited human plasma, r...
|
T12079 |
ML604440
|
1140517-08-3
|
95.24%
|
|
ML604440 is a cell permeable proteasome β1i (LMP2) subunit inhibitor.
|
T2154 |
MG-132
|
133407-82-6
|
95.91%
|
|
MG-132 (Z-Leu-Leu-Leu-al) is a 26S proteasome inhibitor (IC50=100 nM) that is cell-permeable and reversible. MG-132 acts as an autophagy activator and also induc...
|
T8350 |
TPCK
|
402-71-1
|
96.77%
|
|
TPCK is an irreversible inhibitor of chymotrypsin-like proteases that affect cell proliferation, apoptosis, and tumorigenesis
|
T21617 |
MG-115
|
133407-86-0
|
97.12%
|
|
MG-115 (Z-LL-Nva-CHO) is a potent and reversible inhibitor of proteasome , with K i s of 21 nM and 35 nM for 20S and 26S proteasome, respectively. MG-115 specifi...
|