Proton pump

A proton pump is an integral membrane protein pump that builds up a proton gradient across a biological membrane.During evolution, proton pumps have arisen independently on multiple occasions. Thus, not only throughout nature but also within single cells, different proton pumps that are evolutionarily unrelated can be found. Proton pumps are divided into different major classes of pumps that use different sources of energy, have different polypeptide compositions and evolutionary origins.

Cat. No.	製品名	CAS No.	Purity
T6700	Tenatoprazole	113712-98-4	98%
T6700	Tenatoprazole (TU-199), a prodrug of the proton pump inhibitor (PPI) class, can inhibit proton transport (IC50: 3.2 μM).
T2686L	Esomeprazole Sodium	161796-78-7	98%
T2686L	Esomeprazole Sodium ((S)-Omeprazole sodium) is the S-isomer of omeprazole with selective and irreversible proton pump inhibitor activity.Esomeprazole acts as an ...
T21254	Vonoprazan Fumarate	881681-01-2	98%
T21254	Vonoprazan Fumarate (TAK438) , a novel potassium-competitive acid blocker, inhibits gastric acid secretion. Vonoprazan Fumarate (TAK438) inhibited H+,K+-ATPase a...
T16682	Pumaprazole	158364-59-1	98%
T16682	Pumaprazole (BY-841) is an antagonist of a reversible proton pump.
TN1103	Diphyllin	22055-22-7	98%
TN1103	Diphyllin could be characterized as a new V-ATPase inhibitor in treating gastric cancer and inhibiting the phosphorylation of LRP6 in Wnt/β-catenin signaling.
T8388	Vonoprazan	881681-00-1	100%
T8388	Vonoprazan (TAK-438 (free base)) is an orally active potassium-competitive acid blocker.Vonoprazan can be used for the treatment of gastroduodenal ulcer and refl...
T11191	EN6	1808714-73-9	95.16%
T11191	EN6-mediated ATP6V1A modification decouples the v-ATPase from the Rags, leading to inhibition of mTORC1 signaling, increased lysosomal acidification and activati...
T16865	SCH28080	76081-98-6	97.12%
T16865	SCH28080 is a reversible and K+-competitive inhibitor of gastric H+/K+-ATPase with an IC50 value of 20 nM (rabbit microsomal membrane).SCH28080 is a potent inhib...
T0757	Omeprazole	73590-58-6	97.61%
T0757	Omeprazole (Losec) is a proton pump inhibitor (PPI), Omeprazole(Losec) is a potent brain penetrant neutral sphingomyelinase (N-SMase) inhibitor (exosome inhibito...
T40437L	Caloxin 2A1 acetate		98.2%
T40437L	Caloxin 2A1 acetate is an inhibitor of extracellular plasma membrane Ca2+-ATPase (PMCA) peptide. Caloxin 2A1 acetate inhibits Ca2+-dependent formation of the 140...
T20626	Esomeprazole	119141-88-7	98.20%
T20626	Esomeprazole is the S-isomer of omeprazole, inhibits the lysosomal cysteine protease legumain to prevent cancer metastasis. Esomeprazole is a proton pump inhibit...
T17030	Tegoprazan	942195-55-3	98.22%
T17030	Tegoprazan is a potassium-competitive acid blocker and is a potent, oral active, and highly selective inhibitor of gastric H+/K+-ATPase. That could control gastr...
T0161	Pantoprazole Sodium Hydrate	164579-32-2	98.32%
T0161	Pantoprazole Sodium Hydrate (BY1023 (sodium hydrate)) is a proton pump inhibitor drug, used for short-term treatment of erosion and ulceration of the esophagus c...
T21651	Lansoprazole sodium	226904-00-3	98.35%
T21651	Lansoprazole sodium (Lansoprazole (sodium)) is a proton pump inhibitor (PPI) and a potent inhibitor of gastric acidity which is widely used in the therapy of gas...
TQ0184	Chebulinic acid	18942-26-2	98.4%
TQ0184	Chebulinic acid is a potent inhibitor of M. tuberculosis DNA gyrase. It also can inhibit SMAD-3 phosphorylation and H+ K+-ATPase activity.
T6368	Abscisic Acid	21293-29-8	98.57%
T6368	Abscisic Acid (Dormin) is a plant hormone, which is involved in many plant developmental processes, modulates ion homeostasis and metabolism, and inhibits germin...
T10221	Abeprazan hydrochloride	1902954-87-3	98.62%
T10221	Abeprazan hydrochloride (Fexuprazan hydrochloride) is an effective reversible potassium-competitive acid blocker with oral activity, inhibiting H+, K+ -atPase by...
T20714	Levolansoprazole	138530-95-7	98.62%
T20714	Levolansoprazole ((S)-Lansoprazole), a proton pump inhibitor, irreversibly inhibits H+/K+-stimulated ATPase pumps in parietal cells (IC50: 5.2 μM). It also inhib...
T8386	Esomeprazole Magnesium trihydrate	217087-09-7	98.71%
T8386	Esomeprazole Magnesium trihydrate ((S)-Omeprazole magnesium trihydrate) is a proton pump inhibitor indicated for the short-term treatment of gastroesophageal ref...
T2687	Omeprazole sulfide	73590-85-9	98.77%
T2687	Omeprazole sulfide (Ufiprazole), a metabolite of Omeprazole, functions as a proton pump inhibitor.