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SARS-CoV

Severe acute respiratory syndrome coronavirus (SARS-CoV or SARS-CoV-1) is a strain of virus that causes severe acute respiratory syndrome (SARS). It is an enveloped, positive-sense, single-stranded RNA virus which infects the epithelial cells within the lungs. The virus enters the host cell by binding to the ACE2 receptor. It infects humans, bats, and palm civets.
Cat. No. 製品名 CAS No. Purity Chemical Structure
T6573 E 64c 76684-89-4 98%
E 64c (EP 475) , a derivative of E-64, is an irreversible and membrane-permeant cysteine protease inhibitor.
T9606 TC-067533 1093070-10-0 98%
TC-067533 is a Papain-like protease inhibitor with an IC50 of 8.7 μM.
T4686 Simeprevir 923604-59-5 98%
Simeprevir (TMC435) is a potent HCV NS3/4A protease inhibitor, and inhibits HCV replication with EC50 of 8 nM.
T21727 Ivermectin B1a 71827-03-7 98%
Ivermectin B1a is the major (80%) component of commercially available ivermectin and a derivative of Avermectin B1a.
T9618 HeE1-2Tyr 2245195-67-7 98%
HeE1-2Tyr, a pyridobenzothiazole compound, is a flavivirus RNA dependent RNA polymerases (RdRp) inhibitor. It significantly inhibits West Nile, Dengue and SARS-C...
T40276 GS-621763 2647442-13-3 98%
GS-621763, a prodrug of GS-441524, exhibits antiviral activity against SARS-CoV-2 pathogenesis.
T8689 Chloroquine 54-05-7 98%
Chloroquine is a Toll-like receptor inhibitor that inhibits autophagy. Chloroquine has anti-malarial and anti-inflammatory activity and is widely used in the tre...
T77652 SARS-CoV-2 3CLpro-IN-20 878985-00-3 98%
SARS-CoV-2 3CLpro-IN-20 is a covalent SARS-CoV-2 3CLpro inhibitor (IC50s: 0.43 μM,).SARS-CoV-2 3CLpro-IN-20 has potential antiviral activity.
T9293 SSAA09E3 52869-18-8 98%
SSAA09E3 is a novel inhibitor of SARS-CoV replication, acting by preventing fusion of the viral membrane with the host cellular membrane.
T60045 NK01-63 2922281-15-8 98%
NK01-63 (Coronastat) is a potent inhibitor of the SARS-CoV-2 3CL protease.
T60095 CCF0058981 2708934-53-4 98%
CCF0058981 (CCF981) is a 3-chlorophenyl analogue which is a noncovalent SARS-CoV-2 3CL pro (SC2) inhibitor with an IC 50 of 68 nM. CCF0058981 inhibits SC1 (SARS-...
T9617 RdRP-IN-2 98%
RdRP-IN-2 is a RNA dependent RNA polymerase (RdRp) inhibitor. It significantly inhibits SARS-CoV-2 RdRp with an IC50 of 41.2 µM.It also inhibits Feline coronavir...
T76870 Narsoplimab 2108782-45-0 98%
Narsoplimab
Narsoplimab (OMS 721) is a selective whole-human immunoglobulin gamma-4 (IgG4) monoclonal antibody, a mannan-binding lectin-associated serine protease-2 (MASP-2)...
TQ0180 Chebulagic acid 23094-71-5 98%
Chebulagic acid, isolated from the Terminalia chebula Retz, is a COX-LOX dual inhibitor.
T9614 MERS-CoV-IN-1 2245697-92-9 98%
MERS-CoV-IN-1 exhibits excellent inhibitory activity against coronavirus.It is useful as a pharmaceutical composition for preventing coronavirus-induced diseases...
T12502 PLpro inhibitor 1093070-14-4 98%
PLpro inhibitor is a potent papain-like protease (PLpro) inhibitor(IC50 of 2.6 uM)
T8676 FOY 251 71079-09-9 98%
FOY 251 is a proteinase inhibitor, and is an anti-proteolytic active metabolite camostate.
T9331 Bemnifosbuvir hemisulfate 2241337-84-6 98%
Bemnifosbuvir hemisulfate (AT-527) is a potent inhibitor of HCV virus replication.
T1307 Carmofur 61422-45-5
Carmofur (HCFU) is a highly potent acid ceramidase inhibitor, used in the treatment of breast and colorectal cancer. Carmofur has been known to induce leukoencep...
T5188 GC376 sodium 1416992-39-6
GC376 is an inhibitor of 3C-like proteases (3CLpro) with IC50 values range from 0.49~4.35 μM.
E 64c
T6573
E 64c (EP 475) , a derivative of E-64, is an irreversible and membrane-permeant cysteine protease inhibitor.
TC-067533
T9606
TC-067533 is a Papain-like protease inhibitor with an IC50 of 8.7 μM.
Simeprevir
T4686
Simeprevir (TMC435) is a potent HCV NS3/4A protease inhibitor, and inhibits HCV replication with EC50 of 8 nM.
Ivermectin B1a
T21727
Ivermectin B1a is the major (80%) component of commercially available ivermectin and a derivative of Avermectin B1a.
HeE1-2Tyr
T9618
HeE1-2Tyr, a pyridobenzothiazole compound, is a flavivirus RNA dependent RNA polymerases (RdRp) inhibitor. It significantly inhibits West Nile, Dengue and SARS-C...
GS-621763
T40276
GS-621763, a prodrug of GS-441524, exhibits antiviral activity against SARS-CoV-2 pathogenesis.
Chloroquine
T8689
Chloroquine is a Toll-like receptor inhibitor that inhibits autophagy. Chloroquine has anti-malarial and anti-inflammatory activity and is widely used in the tre...
SARS-CoV-2 3CLpro-IN-20
T77652
SARS-CoV-2 3CLpro-IN-20 is a covalent SARS-CoV-2 3CLpro inhibitor (IC50s: 0.43 μM,).SARS-CoV-2 3CLpro-IN-20 has potential antiviral activity.
SSAA09E3
T9293
SSAA09E3 is a novel inhibitor of SARS-CoV replication, acting by preventing fusion of the viral membrane with the host cellular membrane.
NK01-63
T60045
NK01-63 (Coronastat) is a potent inhibitor of the SARS-CoV-2 3CL protease.
CCF0058981
T60095
CCF0058981 (CCF981) is a 3-chlorophenyl analogue which is a noncovalent SARS-CoV-2 3CL pro (SC2) inhibitor with an IC 50 of 68 nM. CCF0058981 inhibits SC1 (SARS-...
RdRP-IN-2
T9617
RdRP-IN-2 is a RNA dependent RNA polymerase (RdRp) inhibitor. It significantly inhibits SARS-CoV-2 RdRp with an IC50 of 41.2 µM.It also inhibits Feline coronavir...
Narsoplimab
T76870
Narsoplimab (OMS 721) is a selective whole-human immunoglobulin gamma-4 (IgG4) monoclonal antibody, a mannan-binding lectin-associated serine protease-2 (MASP-2)...
Chebulagic acid
TQ0180
Chebulagic acid, isolated from the Terminalia chebula Retz, is a COX-LOX dual inhibitor.
MERS-CoV-IN-1
T9614
MERS-CoV-IN-1 exhibits excellent inhibitory activity against coronavirus.It is useful as a pharmaceutical composition for preventing coronavirus-induced diseases...
PLpro inhibitor
T12502
PLpro inhibitor is a potent papain-like protease (PLpro) inhibitor(IC50 of 2.6 uM)
FOY 251
T8676
FOY 251 is a proteinase inhibitor, and is an anti-proteolytic active metabolite camostate.
Bemnifosbuvir hemisulfate
T9331
Bemnifosbuvir hemisulfate (AT-527) is a potent inhibitor of HCV virus replication.
Carmofur
T1307
Carmofur (HCFU) is a highly potent acid ceramidase inhibitor, used in the treatment of breast and colorectal cancer. Carmofur has been known to induce leukoencep...
GC376 sodium
T5188
GC376 is an inhibitor of 3C-like proteases (3CLpro) with IC50 values range from 0.49~4.35 μM.
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